Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Franck P. Martial"'
Autor:
Paul E.A. Humphreys, Steven Woods, Nicola Bates, Kirsty M. Rooney, Fabrizio E. Mancini, Cerys Barclay, Julieta O’Flaherty, Franck P. Martial, Marco A.N. Domingos, Susan J. Kimber
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113502- (2023)
Summary: Optogenetics is a rapidly advancing technology combining photochemical, optical, and synthetic biology to control cellular behavior. Together, sensitive light-responsive optogenetic tools and human pluripotent stem cell differentiation model
Externí odkaz:
https://doaj.org/article/48364f8484364e76b3439618b536e1c7
Autor:
Aghileh S. Ebrahimi, Patrycja Orlowska-Feuer, Qian Huang, Antonio G. Zippo, Franck P. Martial, Rasmus S. Petersen, Riccardo Storchi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract A key step in understanding animal behaviour relies in the ability to quantify poses and movements. Methods to track body landmarks in 2D have made great progress over the last few years but accurate 3D reconstruction of freely moving animal
Externí odkaz:
https://doaj.org/article/d9e5d4812db0416b9e4aa21606550c95
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Introduction: Intrinsically photosensitive retinal ganglion cells (ipRGCs) integrate melanopsin and rod/cone-mediated inputs to signal to the brain. Whilst originally identified as a cell type specialised for encoding ambient illumination, several li
Externí odkaz:
https://doaj.org/article/253e8c508c7b4a9ebe583d99a8044d31
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
The perception of spatial patterns (form vision) is thought to rely on rod and cone cells in the retina. Here, the authors show that a third kind of retinal cell, melanopsin-expressing ganglion cells, can also detect form in humans, under particular
Externí odkaz:
https://doaj.org/article/bd7890b4a7f544a4928571363482a220
Autor:
Cyril G. Eleftheriou, Phillip Wright, Annette E. Allen, Daniel Elijah, Franck P. Martial, Robert J. Lucas
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Intrinsically photosensitive retinal ganglion cells (ipRGCs) express the photopigment melanopsin and project to central targets, allowing them to contribute to both image-forming and non-image forming vision. Recent studies have highlighted chemical
Externí odkaz:
https://doaj.org/article/6b6f0f501d4845c6babafa2d3e6e26e5
Autor:
Timothy M. Brown, Court Harding, David A. Bechtold, Robert J. Lucas, Annette E. Allen, Franck P. Martial, Beatriz Bano-Otalora, Mino D. C. Belle
Publikováno v:
Bano-Otalora, B, Martial, F, Harding, C, Bechtold, D A, Allen, A E, Brown, T M, Belle, M D C & Lucas, R J 2021, ' Bright daytime light enhances circadian amplitude in a diurnal mammal ', Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 22, e2100094118 . https://doi.org/10.1073/pnas.2100094118
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance Light is an important regulator of endogenous circadian clocks. Regular light–dark cycles set circadian phase to ensure synchrony with external time, while irregular or inappropriate light exposure can disrupt circadian rhythms. We ask
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38e6bb3cea5cbc85c7a681713f74cb82
https://www.pnas.org/content/pnas/118/22/e2100094118.full.pdf
https://www.pnas.org/content/pnas/118/22/e2100094118.full.pdf
Publikováno v:
Journal of Neurophysiology. 122:1753-1764
Inherited retinal degenerations encompass a wide range of diseases that result in the death of rod and cone photoreceptors, eventually leading to irreversible blindness. Low vision survives at early stages of degeneration, at which point it could rel
Publikováno v:
Mouland, J, Brown, T, Martial, F & Lucas, R 2021, ' Modulations in irradiance directed at melanopsin, but not cone photoreceptors, reliably alter electrophysiological activity in the suprachiasmatic nucleus and circadian behaviour in mice ', Journal of Pineal Research, vol. 70, no. 4, e12735 . https://doi.org/10.1111/jpi.12735
Intrinsically photosensitive retinal ganglion cells convey intrinsic, melanopsin-based, photoreceptive signals alongside those produced by rods and cones to the suprachiasmatic nucleus (SCN) circadian clock. To date, experimental data suggest that me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86bae30d99aa8bbcf25fa2f47e892a4d
https://doi.org/10.1111/jpi.12735
https://doi.org/10.1111/jpi.12735
Autor:
Sarika Paul, Patrycja Orlowska-Feuer, Jessica Rodgers, Robert J. Lucas, Mino D. C. Belle, Edward R. Ballister, Riccardo Storchi, Timothy M. Brown, Nina Milosavljevic, Franck P. Martial, Beatriz Bano-Otalora, Richard J. McDowell, Annette E. Allen, Jonathan Wynne, Rebecca Hughes, Phillip Wright
Publikováno v:
Rodgers, J, Bano-Otalora, B, Belle, M D C, Paul, S, Hughes, R, Wright, P, McDowell, R, Milosavljevic, N, Orlowska-Feuer, P, Martial, F P, Wynne, J, Ballister, E R, Storchi, R, Allen, A E, Brown, T & Lucas, R J 2021, ' Using a bistable animal opsin for switchable and scalable optogenetic inhibition of neurons ', EMBO reports, pp. e51866 . https://doi.org/10.15252/embr.202051866
There is no consensus on the best optogenetic tool for neuronal inhibition. Lamprey parapinopsin (‘Lamplight’) is a Gi/o-coupled bistable animal opsin that can be activated and deactivated by short and long wavelength light, respectively. Since n
Autor:
Robert J. Lucas, Franck P. Martial, Timothy M. Brown, Mino D. C. Belle, David A. Bechtold, Beatriz Bano-Otalora, Court Harding, Annette E. Allen
Mammalian circadian rhythms are orchestrated by a master pacemaker in the hypothalamic suprachiasmatic nuclei (SCN), which receives information about the 24 h light:dark cycle from the retina. The accepted function of this light signal is to reset ci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::995c1879f5fb985c4961fc84b6e5aba4
https://doi.org/10.1101/2020.06.22.164194
https://doi.org/10.1101/2020.06.22.164194