Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Franck P, Dupuy"'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Infection with the human immunodeficiency virus (HIV), when left untreated, typically leads to disease progression towards acquired immunodeficiency syndrome. Some people living with HIV (PLWH) control their virus to levels below the limit of detecti
Externí odkaz:
https://doaj.org/article/e285ddd8d9c64b71beed535c31b0cf5b
Autor:
Vladimir-Andrey Gimenez-Rivera, Harshita Patel, Franck P. Dupuy, Zoulfia Allakhverdi, Charlie Bouchard, Joaquín Madrenas, Robert Bissonnette, Ciriaco A. Piccirillo, Carolyn Jack
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 369 (2023)
Atopic dermatitis (AD) is known as a skin disease; however, T cell immunopathology found in blood is associated with its severity. Skin Staphylococcus aureus (S. aureus) and associated host–pathogen dynamics are important to chronic T helper 2 (Th2
Externí odkaz:
https://doaj.org/article/c5d66cd79d704e4586a44642c8680529
Autor:
Khlood Alsulami, Franck P. Dupuy, Louise Gilbert, Marc Messier-Peet, Madeleine Durand, Cécile Tremblay, Jean-Pierre Routy, Julie Bruneau, Jean-Guy Baril, Benoit Trottier, Nicole F. Bernard
Publikováno v:
Viruses, Vol 15, Iss 2, p 323 (2023)
Human cytomegalovirus (CMV) infection drives the expansion and differentiation of natural killer (NK) cells with adaptive-like features. We investigated whether age and time on antiretroviral therapy (ART) influenced adaptive NK cell frequency and fu
Externí odkaz:
https://doaj.org/article/1a69c33057ce407781bf6b11bfee009e
Publikováno v:
BMC Immunology, Vol 20, Iss 1, Pp 1-13 (2019)
Abstract Background Natural killer cell responses to virally-infected or transformed cells depend on the integration of signals received through inhibitory and activating natural killer cell receptors. Human Leukocyte Antigen null cells are used in v
Externí odkaz:
https://doaj.org/article/1b862d1749a4499290834968cf3e44e6
Autor:
Delphine Planas, Amélie Pagliuzza, Rosalie Ponte, Augustine Fert, Laurence Raymond Marchand, Marta Massanella, Annie Gosselin, Vikram Mehraj, Franck P Dupuy, Stéphane Isnard, Jean-Philippe Goulet, Sylvie Lesage, Eric A. Cohen, Mager Peter Ghali, Jonathan B. Angel, Nicolas Chomont, Jean-Pierre Routy, Petronela Ancuta
Publikováno v:
EBioMedicine, Vol 65, Iss , Pp 103270- (2021)
Background: Chronic inflammation and residual HIV transcription persist in people living with HIV (PLWH) receiving antiretroviral therapy (ART), thus increasing the risk of developing non-AIDS co-morbidities. The mechanistic target of rapamycin (mTOR
Externí odkaz:
https://doaj.org/article/b77dad2e089643938c96c3b816fc71fb
Publikováno v:
Viruses, Vol 14, Iss 6, p 1143 (2022)
Some people, known as HIV-exposed seronegative (HESN) individuals, remain uninfected despite high levels of exposure to HIV. Understanding the mechanisms underlying their apparent resistance to HIV infection may inform strategies designed to protect
Externí odkaz:
https://doaj.org/article/e96e7637992a47adaccdcb1bd7c5944b
Autor:
Sanket Kant, Ningyu Zhang, Alexandre Barbé, Jean-Pierre Routy, Cécile Tremblay, Réjean Thomas, Jason Szabo, Pierre Côté, Benoit Trottier, Roger LeBlanc, Danielle Rouleau, Marianne Harris, Franck P. Dupuy, Nicole F. Bernard
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Antibody dependent (AD) functions such as AD cellular cytotoxicity (ADCC) were associated with lower viral load (VL) in untreated HIV progressors and protection from HIV infection in the modestly protective RV144 HIV vaccine trial. Target cells used
Externí odkaz:
https://doaj.org/article/2253ebfb967e4f749bdea9c60e68a83e
Autor:
Franck P. Dupuy, Sanket Kant, Alexandre Barbé, Jean-Pierre Routy, Julie Bruneau, Bertrand Lebouché, Cécile Tremblay, Marzena Pazgier, Andrés Finzi, Nicole F. Bernard
Publikováno v:
mBio, Vol 10, Iss 6 (2019)
ABSTRACT Measuring Envelope (Env)-specific antibody (Ab)-dependent cellular cytotoxicity (ADCC)-competent Abs in HIV+ plasma is challenging because Env displays distinctive epitopes when present in a native closed trimeric conformation on infected ce
Externí odkaz:
https://doaj.org/article/5431e290a44f41d0a90a711ffff01921
Autor:
Vikram Mehraj, Rayoun Ramendra, Stéphane Isnard, Franck P. Dupuy, Bertrand Lebouché, Cecilia Costiniuk, Réjean Thomas, Jason Szabo, Jean-Guy Baril, Benoit Trottier, Pierre Coté, Roger LeBlanc, Madéleine Durand, Carl Chartrand-Lefebvre, Ido Kema, Yonglong Zhang, Malcolm Finkelman, Cécile Tremblay, Jean-Pierre Routy
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Background: CXCL13 is preferentially secreted by Follicular Helper T cells (TFH) to attract B cells to germinal centers. Plasma levels of CXCL13 have been reported to be elevated during chronic HIV-infection, however there is limited data on such ele
Externí odkaz:
https://doaj.org/article/2e21b03fc5874eab832913ec74b69dd7
Autor:
Christina Gavegnano, Jessica H Brehm, Franck P Dupuy, Aarthi Talla, Susan Pereira Ribeiro, Deanna A Kulpa, Cheryl Cameron, Stephanie Santos, Selwyn J Hurwitz, Vincent C Marconi, Jean-Pierre Routy, Laurent Sabbagh, Raymond F Schinazi, Rafick Pierre Sékaly
Publikováno v:
PLoS Pathogens, Vol 13, Iss 12, p e1006740 (2017)
Despite advances in the treatment of HIV infection with ART, elucidating strategies to overcome HIV persistence, including blockade of viral reservoir establishment, maintenance, and expansion, remains a challenge. T cell homeostasis is a major drive
Externí odkaz:
https://doaj.org/article/4317a5f5021746d493577bcfb4b68481