Photoswitchable glycoligands targeting Pseudomonas aeruginosa LecA

Autor: Yu Fan, Ahmed El Rhaz, Stéphane Maisonneuve, Emilie Gillon, Maha Fatthalla, Franck Le Bideau, Guillaume Laurent, Samir Messaoudi, Anne Imberty, Juan Xie

Publikováno v: Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 1486-1496 (2024)

Biofilm formation is one of main causes of bacterial antimicrobial resistance infections. It is known that the soluble lectins LecA and LecB, produced by Pseudomonas aeruginosa, play a key role in biofilm formation and lung infection. Bacterial lecti

Externí odkaz: https://doaj.org/article/d019338eefbe404499014f5394a05f6d

Organo-catalyzed/initiated ring opening co-polymerization of cyclic anhydrides and epoxides: an emerging story

Autor: Béatrice Jacques, Samuel Dagorne, Françoise Dumas, Samir Messaoudi, Franck Le Bideau, Dmytro Ryzhakov, Gaël Printz

Publikováno v: Polymer Chemistry
Polymer Chemistry, Royal Society of Chemistry-RSC, 2021, 12 (20), pp.2932-2946. ⟨10.1039/d1py00020a⟩

Polyesters are omnipresent in our everyday lives and their synthesis via eco-friendly methods is becoming a major challenge today. The co-polymerization of cyclic anhydrides and epoxides was first reported by Fischer in 1960 involving a tertiary amin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3054dc5ada6b7298a38d71d2f31a9554
https://doi.org/10.1039/d1py00020a

Synthesis of axially chiral biaryl thioglycosides through thiosugar-directed Pd-catalyzed asymmetric C-H activation

Autor: Mouad Alami, Vincent Gandon, Maha I. Fatthalla, Franck Le Bideau, Etienne Brachet, Nicolas Grimblat, Samir Messaoudi

Publikováno v: Chemical Communications
Chemical Communications, Royal Society of Chemistry, 2021, 57 (80), pp.10355-10358. ⟨10.1039/d1cc03971g⟩

Herein we report for the first time that the thiosugar moiety can be used both as a directing group enabling the regioselective activation of a C–H bond of biaryl scaffolds and as a chiral source inducing axial chirality. Our approach enables the e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbefd1d34c0f8f40658067817537258b
https://pubmed.ncbi.nlm.nih.gov/34533145

Emerging Organometallic Methods for the Synthesis of C‐Branched (Hetero)aryl, Alkenyl, and Alkyl Glycosides: C−H Functionalization and Dual Photoredox Approaches

Autor: Samir Messaoudi, Franck Le Bideau, Angélique Ferry, Morgane de Robichon, Juba Ghouilem

Publikováno v: Chemistry-A European Journal
Chemistry-A European Journal, Wiley-VCH Verlag, 2020, ⟨10.1002/chem.202003267⟩
Chemistry-A European Journal, Wiley-VCH Verlag, 2021, 27 (2), pp.491-511. ⟨10.1002/chem.202003267⟩

International audience; Transition-metal catalyzed C-H functionalization and photoredox-nickel dual catalysis have emerged as innovative and powerful avenues for the synthesis of C-branched glycosides. These two concepts have been recently establishe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4800ab23d76683f84803ee93d437df1
https://hal.archives-ouvertes.fr/hal-03009617

Straightforward access to densely substituted chiral succinimides through enantioselective organocatalyzed Michael addition of α-alkyl-cyclic ketones to maleimides

Autor: Franck Le Bideau, Pascal Retailleau, Lai Wei, Françoise Dumas, Li Chen

Publikováno v: Organic Chemistry Frontiers
Organic Chemistry Frontiers, Royal Society of Chemistry, 2020, 7 (10), pp.1224-1229. ⟨10.1039/C9QO01463B⟩

International audience; A simple organocatalytic system provides efficient access to a series of densely substituted chiral succinimides bearing a quaternary-tertiary carbon stereocenter sequence in good yields, high diastereo-and enantioselectivitie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee78f5ca9849571aae3560c0ed200d88
https://hal.archives-ouvertes.fr/hal-03009508