Výsledky vyhledávání - "Franck Ladam"

Akademický článek

ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis

Autor: Mandy Dumortier, Franck Ladam, Isabelle Damour, Sophie Vacher, Ivan Bièche, Nathalie Marchand, Yvan de Launoit, David Tulasne, Anne Chotteau-Lelièvre

Publikováno v: Breast Cancer Research, Vol 20, Iss 1, Pp 1-18 (2018)

Abstract Background The ETS transcription factor ETV4 is involved in the main steps of organogenesis and is also a significant mediator of tumorigenesis and metastasis, such as in breast cancer. Indeed, ETV4 is overexpressed in breast tumors and is a

Externí odkaz: https://doaj.org/article/0d2fa4fe185e4fe9982595bdd3b8c81f

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Akademický článek

TALE factors use two distinct functional modes to control an essential zebrafish gene expression program

Autor: Franck Ladam, William Stanney, Ian J Donaldson, Ozge Yildiz, Nicoletta Bobola, Charles G Sagerström

Publikováno v: eLife, Vol 7 (2018)

TALE factors are broadly expressed embryonically and known to function in complexes with transcription factors (TFs) like Hox proteins at gastrula/segmentation stages, but it is unclear if such generally expressed factors act by the same mechanism th

Externí odkaz: https://doaj.org/article/8bbe1dc24903414fb9e2180128cc2383

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Akademický článek

A tissue-specific, Gata6-driven transcriptional program instructs remodeling of the mature arterial tree

Autor: Marta Losa, Victor Latorre, Munazah Andrabi, Franck Ladam, Charles Sagerström, Ana Novoa, Peyman Zarrineh, Laure Bridoux, Neil A Hanley, Moises Mallo, Nicoletta Bobola

Publikováno v: eLife, Vol 6 (2017)

Connection of the heart to the systemic circulation is a critical developmental event that requires selective preservation of embryonic vessels (aortic arches). However, why some aortic arches regress while others are incorporated into the mature aor

Externí odkaz: https://doaj.org/article/f1cfd7cfe3f74e32afcf96f2bd5d615f

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