Zobrazeno 1 - 10 of 666 pro vyhledávání: '"Franck E Nicolini"'
1
Akademický článek
A minimal rupture cascade model for living cell plasticity
Autor: Stefano Polizzi, Bastien Laperrousaz, Francisco J Perez-Reche, Franck E Nicolini, Véronique Maguer Satta, Alain Arneodo, Françoise Argoul
Publikováno v: New Journal of Physics, Vol 20, Iss 5, p 053057 (2018)
Under physiological and pathological conditions, cells experience large forces and deformations that often exceed the linear viscoelastic regime. Here we drive CD34 ^+ cells isolated from healthy and leukemic bone marrows in the highly nonlinear elas
Externí odkaz: https://doaj.org/article/dcbe6d383479467592641e36cfbb4b4f
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2
Akademický článek
Incidence and outcome of BCR‐ABL mutated chronic myeloid leukemia patients who failed to tyrosine kinase inhibitors
Autor: Gabriel Etienne, Stéphanie Dulucq, Françoise Huguet, Anna Schmitt, Axelle Lascaux, Sandrine Hayette, Marie‐Pierre Fort, Pierre Sujobert, Fontanet Bijou, Stéphane Morisset, Suzanne Tavitian, Audrey Bidet, Beatrice Turcq, Fanny Robbesyn, Claudine Chollet, Francis Belloc, Françoise Durrieu, François‐Xavier Mahon, Franck E. Nicolini
Publikováno v: Cancer Medicine, Vol 8, Iss 11, Pp 5173-5182 (2019)
Abstract Purpose To assess the incidence of BCR‐ABL kinase domain (KD) mutation detection and its prognostic significance in chronic phase chronic myeloid leukemia (CP‐CML) patients treated with tyrosine kinase inhibitors (TKIs). Patients and Met
Externí odkaz: https://doaj.org/article/6e01c6179d7a4668b2becca6369a87e0
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3
Akademický článek
Performances of Targeted RNA Sequencing for the Analysis of Fusion Transcripts, Gene Mutation, and Expression in Hematological Malignancies
Autor: Sandrine Hayette, Béatrice Grange, Maxime Vallee, Claire Bardel, Sarah Huet, Isabelle Mosnier, Kaddour Chabane, Thomas Simonet, Marie Balsat, Maël Heiblig, Isabelle Tigaud, Franck E. Nicolini, Sylvain Mareschal, Gilles Salles, Pierre Sujobert
Publikováno v: HemaSphere, Vol 5, Iss 2, p e522 (2021)
RNA sequencing holds great promise to improve the diagnostic of hematological malignancies, because this technique enables to detect fusion transcripts, to look for somatic mutations in oncogenes, and to capture transcriptomic signatures of nosologic
Externí odkaz: https://doaj.org/article/6d0a336b44874bb2ae53232808000c7c
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7
Data from Implication of the Autologous Immune System in BCR–ABL Transcript Variations in Chronic Myelogenous Leukemia Patients Treated with Imatinib
Autor: Doron Levy, Franck E. Nicolini, Hélène Labussière-Wallet, Jérémy Ruby, Samuel Bernard, Raouf El Cheikh, Thomas Lepoutre, Geoffrey D. Clapp
Imatinib and other tyrosine kinase inhibitors (TKI) have improved treatment of chronic myelogenous leukemia (CML); however, most patients are not cured. Deeper mechanistic understanding may improve TKI combination therapies to better control the resi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c27bf527d0a2c1957063530e927f79
https://doi.org/10.1158/0008-5472.c.6507360
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