Zobrazeno 1 - 10 of 721 pro vyhledávání: '"Franck E Nicolini"'
1
Akademický článek
The CML experience to elucidate the role of innate T-cells as effectors in the control of residual cancer cells and as potential targets for cancer therapy
Autor: Amandine Decroos, Sarah Meddour, Marine Demoy, Nathalie Piccirilli, Philippe Rousselot, Franck E. Nicolini, Stéphanie Ragot, Jean-Marc Gombert, André Herbelin, Alice Barbarin, Emilie Cayssials
Publikováno v: Frontiers in Immunology, Vol 15 (2024)
Considering the general view that unconventional immune effectors play a major role in antitumor immunity, we recently postulated that the distinct new innate CD8 T-cell pool (co-expressing the transcription factor Eomesodermin and innate markers suc
Externí odkaz: https://doaj.org/article/bfad382e614a4f12abe94c7ae4501171
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4
Akademický článek
Incidence and outcome of BCR‐ABL mutated chronic myeloid leukemia patients who failed to tyrosine kinase inhibitors
Autor: Gabriel Etienne, Stéphanie Dulucq, Françoise Huguet, Anna Schmitt, Axelle Lascaux, Sandrine Hayette, Marie‐Pierre Fort, Pierre Sujobert, Fontanet Bijou, Stéphane Morisset, Suzanne Tavitian, Audrey Bidet, Beatrice Turcq, Fanny Robbesyn, Claudine Chollet, Francis Belloc, Françoise Durrieu, François‐Xavier Mahon, Franck E. Nicolini
Publikováno v: Cancer Medicine, Vol 8, Iss 11, Pp 5173-5182 (2019)
Abstract Purpose To assess the incidence of BCR‐ABL kinase domain (KD) mutation detection and its prognostic significance in chronic phase chronic myeloid leukemia (CP‐CML) patients treated with tyrosine kinase inhibitors (TKIs). Patients and Met
Externí odkaz: https://doaj.org/article/6e01c6179d7a4668b2becca6369a87e0
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5
Akademický článek
Performances of Targeted RNA Sequencing for the Analysis of Fusion Transcripts, Gene Mutation, and Expression in Hematological Malignancies
Autor: Sandrine Hayette, Béatrice Grange, Maxime Vallee, Claire Bardel, Sarah Huet, Isabelle Mosnier, Kaddour Chabane, Thomas Simonet, Marie Balsat, Maël Heiblig, Isabelle Tigaud, Franck E. Nicolini, Sylvain Mareschal, Gilles Salles, Pierre Sujobert
Publikováno v: HemaSphere, Vol 5, Iss 2, p e522 (2021)
RNA sequencing holds great promise to improve the diagnostic of hematological malignancies, because this technique enables to detect fusion transcripts, to look for somatic mutations in oncogenes, and to capture transcriptomic signatures of nosologic
Externí odkaz: https://doaj.org/article/6d0a336b44874bb2ae53232808000c7c
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9
Data from Implication of the Autologous Immune System in BCR–ABL Transcript Variations in Chronic Myelogenous Leukemia Patients Treated with Imatinib
Autor: Doron Levy, Franck E. Nicolini, Hélène Labussière-Wallet, Jérémy Ruby, Samuel Bernard, Raouf El Cheikh, Thomas Lepoutre, Geoffrey D. Clapp
Imatinib and other tyrosine kinase inhibitors (TKI) have improved treatment of chronic myelogenous leukemia (CML); however, most patients are not cured. Deeper mechanistic understanding may improve TKI combination therapies to better control the resi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c27bf527d0a2c1957063530e927f79
https://doi.org/10.1158/0008-5472.c.6507360
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