Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Franck C. Courtes"'
Publikováno v:
PMC
The mTOR pathway is a conserved master regulator of translational activity that influences the fate of industrially relevant CHO cell cultures, yet its molecular mechanisms remain unclear. Interestingly, rapamycin specific inhibition of the mTOR path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bcd4d62b7208692428ffc0eb62bcd21
https://doi.org/10.1016/j.jbiotec.2014.01.024
https://doi.org/10.1016/j.jbiotec.2014.01.024
Autor:
Sze Wai Ng, Hsueh Lee Lim, Bernard Loo, Franck C. Courtes, Miranda G.S. Yap, Niki S.C. Wong, Leah A. Vardy, Geoffrey Koh, Joyce Lin, Dong-Yup Lee
Publikováno v:
Journal of Biotechnology. 167:215-224
We report the first investigation of translational efficiency on a global scale, also known as translatome, of a Chinese hamster ovary (CHO) DG44 cell line producing monoclonal antibodies (mAb). The translatome data was generated via combined use of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::604c9047185b91b74ecbb64c965da7b5
https://doi.org/10.1016/j.jbiotec.2013.07.010
https://doi.org/10.1016/j.jbiotec.2013.07.010
Autor:
Muriel Bardor, Niki S.C. Wong, Miranda G.S. Yap, Dong-Yup Lee, Franck C. Courtes, Leah A. Vardy
Publikováno v:
New Biotechnology
New Biotechnology, Elsevier, 2014, 31 (5), pp.514-523. ⟨10.1016/j.nbt.2013.10.003⟩
New Biotechnology, Elsevier, 2014, 31 (5), pp.514-523. ⟨10.1016/j.nbt.2013.10.003⟩
The mammalian target of rapamycin (mTOR) pathway plays essential roles in the regulation of translational activity in many eukaryotes. Thus, from a bioprocessing point of view, understanding its molecular mechanisms may provide potential avenues for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b70b3c8f0388bda5c14ab7b79a5a5a9
https://hal-normandie-univ.archives-ouvertes.fr/hal-01843924
https://hal-normandie-univ.archives-ouvertes.fr/hal-01843924
