Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Franck, Mortreux"'
Autor:
Mariam Shallak, Tiziana Alberio, Mauro Fasano, Maria Monti, Ilaria Iacobucci, Julien Ladet, Franck Mortreux, Roberto S. Accolla, Greta Forlani
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Adult T-cell leukemia/lymphoma (ATL) is a T-cell lymphoproliferative neoplasm caused by the human T-cell leukemia virus type 1 (HTLV-1). Two viral proteins, Tax-1 and HBZ play important roles in HTLV-1 infectivity and in HTLV-1-associated pathologies
Externí odkaz:
https://doaj.org/article/401e1068b2264f0f86bc77d4eebebdb7
Autor:
Lamya Ben Ameur, Paul Marie, Morgan Thenoz, Guillaume Giraud, Emmanuel Combe, Jean-Baptiste Claude, Sebastien Lemaire, Nicolas Fontrodona, Hélène Polveche, Marine Bastien, Antoine Gessain, Eric Wattel, Cyril F. Bourgeois, Didier Auboeuf, Franck Mortreux
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The nuclear factors κB (NF-κB) is a transcription factor involved in immune functions, inflammation, and cancer. Here, the authors show that the NF-κB factor RELA regulates splicing of target genes by recruiting DDX17 on chromatin upon expression
Externí odkaz:
https://doaj.org/article/b9b58d9a3e674e579917447295972cb5
Autor:
Sébastien Lemaire, Nicolas Fontrodona, Fabien Aubé, Jean-Baptiste Claude, Hélène Polvèche, Laurent Modolo, Cyril F. Bourgeois, Franck Mortreux, Didier Auboeuf
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-21 (2019)
Abstract Background Nucleotide composition bias plays an important role in the 1D and 3D organization of the human genome. Here, we investigate the potential interplay between nucleotide composition bias and the regulation of exon recognition during
Externí odkaz:
https://doaj.org/article/5a5d20b3977c4af3acdd667e1f6ebabc
Autor:
Charlotte Vandermeulen, Tina O'Grady, Jerome Wayet, Bartimee Galvan, Sibusiso Maseko, Majid Cherkaoui, Alice Desbuleux, Georges Coppin, Julien Olivet, Lamya Ben Ameur, Keisuke Kataoka, Seishi Ogawa, Olivier Hermine, Ambroise Marcais, Marc Thiry, Franck Mortreux, Michael A Calderwood, Johan Van Weyenbergh, Jean-Marie Peloponese, Benoit Charloteaux, Anne Van den Broeke, David E Hill, Marc Vidal, Franck Dequiedt, Jean-Claude Twizere
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009919 (2021)
Viral infections are known to hijack the transcription and translation of the host cell. However, the extent to which viral proteins coordinate these perturbations remains unclear. Here we used a model system, the human T-cell leukemia virus type 1 (
Externí odkaz:
https://doaj.org/article/768541b3f7ce458ea9bab656e35d5479
Autor:
Caroline Vindry, Olivia Guillin, Philippe Wolff, Paul Marie, Franck Mortreux, Philippe E Mangeot, Théophile Ohlmann, Laurent Chavatte
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 2023, ⟨10.1093/nar/gkad482⟩
Nucleic Acids Research, 2023, ⟨10.1093/nar/gkad482⟩
The selenocysteine (Sec) tRNA (tRNA[Ser]Sec) governs Sec insertion into selenoproteins by the recoding of a UGA codon, typically used as a stop codon. A homozygous point mutation (C65G) in the human tRNA[Ser]Sec acceptor arm has been reported by two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d63539fc597931f08e32ae5f0318ae7f
https://hal.science/hal-04136959/document
https://hal.science/hal-04136959/document
Autor:
Eric Wattel, Franck Mortreux, Lydia Campos, Denis Guyotat, Jérôme Cornillon, Emmanuelle Tavernier-Tardy, Olivier Kosmider, Pierre Fenaux, Lionel Adès, Pascale Flandrin-Gresta, Patrick Auberger, Guillaume Robert, Delphine Maucort-Boulch, Aminetou Mint Mohamed, Catherine Koering, Françoise Solly
DNMT1 protein expression in SKM1 AZA-sensitive (-S) versus AZA-resistant clones (-R). The Figure corresponds to the Figure 1B with signal quantification performed with ImageJ software. The data are expressed as mean {plus minus} SD of three independe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35baa83a1e5afb47658f17913074c52e
https://doi.org/10.1158/1078-0432.22462098
https://doi.org/10.1158/1078-0432.22462098
Autor:
Eric Wattel, Franck Mortreux, Lydia Campos, Denis Guyotat, Jérôme Cornillon, Emmanuelle Tavernier-Tardy, Olivier Kosmider, Pierre Fenaux, Lionel Adès, Pascale Flandrin-Gresta, Patrick Auberger, Guillaume Robert, Delphine Maucort-Boulch, Aminetou Mint Mohamed, Catherine Koering, Françoise Solly
Pathway enrichment analysis. For ontology analysis, gene lists were analyzed using DAVID software (KEGG pathways). The complete set of genes featured in the microarrays was used as the reference background. The three numbers on the right represent th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e2c397ea112d5d042ba70b54c08094
https://doi.org/10.1158/1078-0432.22462101
https://doi.org/10.1158/1078-0432.22462101
Autor:
Eric Wattel, Franck Mortreux, Lydia Campos, Denis Guyotat, Jérôme Cornillon, Emmanuelle Tavernier-Tardy, Olivier Kosmider, Pierre Fenaux, Lionel Adès, Pascale Flandrin-Gresta, Patrick Auberger, Guillaume Robert, Delphine Maucort-Boulch, Aminetou Mint Mohamed, Catherine Koering, Françoise Solly
Purpose: Azacitidine inhibits DNA methyltransferases, including DNMT1, and is currently the standard of care for patients with higher-risk myelodysplastic syndrome (HRMDS) or low blast count acute myeloid leukemia (AML).Experimental Design: The expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2472094837fbe0d8674a87ab846bbb9a
https://doi.org/10.1158/1078-0432.c.6525006.v1
https://doi.org/10.1158/1078-0432.c.6525006.v1
Autor:
Franck Mortreux, Eric Wattel, Catherine Legras-Lachuer, Nicolas Nazaret, Marie-Hélène Delfau-Larue, Olivier Gout, Antoine Gessain, Christiane Pinatel, Morgan Thenoz, Céline Vernin
Supplemental Figure 2. Expression levels of pri-miR-17 and pri-miR-21 in cloned CD4+ T-cells derived from HTLV-1-infected individuals.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab3230a7bafbb5a3daa337252668e6e
https://doi.org/10.1158/0008-5472.22404128
https://doi.org/10.1158/0008-5472.22404128
Autor:
Franck Mortreux, Eric Wattel, Catherine Legras-Lachuer, Nicolas Nazaret, Marie-Hélène Delfau-Larue, Olivier Gout, Antoine Gessain, Christiane Pinatel, Morgan Thenoz, Céline Vernin
Supplemental Figure 1. A. miRNA expression in cloned T-cells derived from HTLV-1-infected individuals without malignancies. B. Heatmap of expression patterns of 23 miRNAs, Tax and HBZ in 70 clones (34 CD4+) derived from infected individuals.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72975e5920f2a0a430e0b3967700d2e5
https://doi.org/10.1158/0008-5472.22404131.v1
https://doi.org/10.1158/0008-5472.22404131.v1