Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Franciszek Saczewski"'
Autor:
Anna Makowska, Franciszek Sączewski, Patrick J. Bednarski, Maria Gdaniec, Łukasz Balewski, Magdalena Warmbier, Anita Kornicka
Publikováno v:
Molecules, Vol 27, Iss 21, p 7155 (2022)
A series of copper(II) complexes of 2-imino-2H-chromen-3-yl-1,3,5-triazines 2a-h, 3-(benzoxazol-2-yl)-2H-chromen-2-imines 4a-b, and 3-(benzothiazol-2-yl)-2H-chromen-2-imines 6a-c were obtained by reacting of appropriate 2-iminocoumarin ligands L1a-h,
Externí odkaz:
https://doaj.org/article/647486d1f571475bb7cf1fa2fad3e0b1
Autor:
Łukasz Balewski, Franciszek Sączewski, Patrick J. Bednarski, Lisa Wolff, Anna Nadworska, Maria Gdaniec, Anita Kornicka
Publikováno v:
Molecules, Vol 25, Iss 24, p 5924 (2020)
The appropriate 1-arylhydrazinecarbonitriles 1a–c are subjected to the reaction with 2-chloro-4,5-dihydro-1H-imidazole (2), yielding 7-(4,5-dihydro-1H-imidazol-2-yl)-2-aryl-6,7-dihydro-2H-imidazo[2,1-c][1,2,4]triazol-3(5H)-imines 3a–c, which are
Externí odkaz:
https://doaj.org/article/42efec82959246fdb9a0dd1e71d22f71
Autor:
Maria Gdaniec, Jarosław Sączewski, Karolina Lisewska, Agnieszka Kiedrowska, Marta Łobocka, Monika Samsel, Anna Kuchnio, Franciszek Sączewski, Patrick J. Bednarski
Publikováno v:
Molecules, Vol 15, Iss 3, Pp 1113-1126 (2010)
The course of reaction of aryl and heteroaryl sulfonamides with diphenylcarbonate (DPC) and 4-dimethylaminopyridine (DMAP) was found to depend on the pKa of the sulfonamide used. Aryl sulfonamides with pKa ~ 10 gave 4-dimethylamino-pyridinium arylsul
Externí odkaz:
https://doaj.org/article/16dec54163c5414d86f5ac752794aa7b
Publikováno v:
Acta Crystallographica Section E, Vol 66, Iss 6, Pp o1486-o1486 (2010)
The structure of the title compound, C12H16N5+·I−, shows that the methylation reaction with CH3I occurred at the imine N atom at position 5 of the 3,6,7,8a-tetrahydro-2H-diimidazo[1,2-c:1′,2′-e]pyrido[1,2-a][1,3,5]triazine system. In the catio
Externí odkaz:
https://doaj.org/article/36476c0a6aad4c39899c9e19d37c7c36
Autor:
Konrad, Boblewski, Artur, Lehmann, Aleksandra, Marchwinska, Anita, Kornicka, Aleksandra, Wasilewska, Franciszek, Saczewski, Apolonia, Rybczynska
Publikováno v:
Acta poloniae pharmaceutica. 74(2)
Since clonidine was introduced in clinical practice, attempts are still made to obtain substances capable of centrally controlling blood pressure, however with pharmacological profile better than currently avail- able, such as moxonidine and rilmenid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b9741e39f9ba9f6afbd980d66ea3772
https://pubmed.ncbi.nlm.nih.gov/29624262
https://pubmed.ncbi.nlm.nih.gov/29624262
Autor:
Martyna Korcz, Lukasz Sitek, Franciszek Saczewski, Ewa Romejko, Patrick J. Bednarski, Monika Wojciechowska, Anita Kornicka, Piotr Szumlas, Aneta Sakowicz
Publikováno v:
Medicinal Chemistry. 13
Background N-substituted 3-amino-1H-indazoles represent an interesting class of biologically active compounds. Among them, derivatives containing phenylurea moiety are of particular interest. Such compounds have been found to possess inhibitory activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff859797b8d0607693e0ec58d4c8adbe
https://doi.org/10.2174/1573406413666170306114401
https://doi.org/10.2174/1573406413666170306114401
Autor:
Daqing Ma, Franciszek Saczewski, Jianteng Gu, Artur Lehmann, Shayna Laird, Helena R. Watts, Apolonia Rybczyńska, Alan L. Hudson, Jaroslaw Saczewski, Jonne M. Laurila, Konrad Boblewski, Mika Scheinin
Publikováno v:
Bioorganic & Medicinal Chemistry. 20:108-116
A series of 2-[(heteroaryl)methyl]imidazolines was synthesized and tested for their activities at α(1)- and α(2)-adrenoceptors and imidazoline I(1) and I(2) receptors. The most active 2-[(indazol-1-yl)methyl]imidazolines showed high or moderate aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5704534e7442e220f82b5526c8aba63
https://doi.org/10.1016/j.bmc.2011.11.025
https://doi.org/10.1016/j.bmc.2011.11.025
Autor:
Jaroslaw Saczewski, Agnieszka Kiedrowska, Franciszek Saczewski, Karolina Lisewska, Anna Kuchnio, Maria Gdaniec, Marta Łobocka, Monika Samsel, Patrick J. Bednarski
Publikováno v:
Molecules, Vol 15, Iss 3, Pp 1113-1126 (2010)
Molecules; Volume 15; Issue 3; Pages: 1113-1126
Molecules
Molecules; Volume 15; Issue 3; Pages: 1113-1126
Molecules
The course of reaction of aryl and heteroaryl sulfonamides with diphenylcarbonate (DPC) and 4-dimethylaminopyridine (DMAP) was found to depend on the pKa of the sulfonamide used. Aryl sulfonamides with pKa approximately 10 gave 4-dimethylamino-pyridi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f3aef3d97b98c318af25f4b205c5643
http://www.mdpi.com/1420-3049/15/3/1113/
http://www.mdpi.com/1420-3049/15/3/1113/
Autor:
Łukasz Balewski, Franciszek Saczewski
Publikováno v:
Expert Opinion on Therapeutic Patents. 19:1417-1448
The guanidine group defines chemical and physicochemical properties of many compounds of medical interest and guanidine-containing derivatives constitute a very important class of therapeutic agents suitable for the treatment of a wide spectrum of di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee2783fe591ad9eda4fbe4951c8071cf
https://doi.org/10.1517/13543770903216675
https://doi.org/10.1517/13543770903216675
Publikováno v:
Archiv der Pharmazie. 340:333-338
A series of four Cu(II) dichlorides with N-(4,5-dihydro-1H-imidazol-2-yl)azoles as chelating ligands has been prepared and characterized by IR, UV-vis spectroscopy, and X-ray crystallography. The complex [2-(4,5-dihydro-1H-imidazol-2-yl)-1H-benzotria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1695af1fd77f0b22b3e38c97564bb342
https://doi.org/10.1002/ardp.200700021
https://doi.org/10.1002/ardp.200700021