Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Franciscus Schuit"'
Publikováno v:
Diabetologia. 42:1199-1203
Aims/hypothesis. Interleukin-1β is a putative mediator of pancreatic beta-cell dysfunction and damage in Type I (insulin-dependent) diabetes mellitus. To better understand the molecular mechanisms involved in IL-1β effects, we carried out a differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64728314715dbe036f69e1076089aec2
https://doi.org/10.1007/s001250051292
https://doi.org/10.1007/s001250051292
Autor:
Lei Jiang, Benedicte Brackeva, Zhidong Ling, Gertjan Kramer, Aerts, J., Franciscus Schuit, Bart Keymeulen, Daniel Pipeleers, Frans Gorus, Geert Martens
Publikováno v:
Vrije Universiteit Brussel
There is a need for plasma-based tests that can directly measure the extent of beta cell injury in vivo, in patients receiving islet grafts and in animal models. Here we propose protein phosphatase 1, regulatory (inhibitor) subunit 1A (PPP1R1A) as no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::32afe5815cb90d2eec23398dd17af632
https://biblio.vub.ac.be/vubir/potential-of-protein-phosphatase-inhibitor-1-as-biomarker-of-pancreatic-beta-cell-injury-in-vitro-and-in-vivo(b794ee12-2a96-4466-a1a0-72b8f318183f).html
https://biblio.vub.ac.be/vubir/potential-of-protein-phosphatase-inhibitor-1-as-biomarker-of-pancreatic-beta-cell-injury-in-vitro-and-in-vivo(b794ee12-2a96-4466-a1a0-72b8f318183f).html
Autor:
Ellingsgaard, H., Ja Ehses, Elisabeth Hammar, Leentje Van Lommel, Quintens, R., Geert Martens, Kerr-Conte, J., François Pattou, Berney, T., Daniel Pipeleers, Philippe Halban, Franciscus Schuit, Donath, M.
Publikováno v:
Vrije Universiteit Brussel
Interleukin-6 (IL-6) is systemically elevated in obesity and is a predictive factor to develop type 2 diabetes. Pancreatic islet pathology in type 2 diabetes is characterized by reduced beta-cell function and mass, an increased proportion of alpha-ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::04914ed484237e4c63afb4865793bc60
https://biblio.vub.ac.be/vubir/interleukin6-regulates-pancreatic-alfacell-mass-expansion(c8b3e7e4-5579-4419-aed5-bbdf2c222f04).html
https://biblio.vub.ac.be/vubir/interleukin6-regulates-pancreatic-alfacell-mass-expansion(c8b3e7e4-5579-4419-aed5-bbdf2c222f04).html
Publikováno v:
Vrije Universiteit Brussel
xxx
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::20771cc3ee35acff367563380d589cda
https://biblio.vub.ac.be/vubir/immunemediated-type-1-diabetes-presenting-before-age-15-years-lack-of-relation-between-hla-dq-genotypes-and-clinical-disease-phenotype(0057d659-6d61-47ac-b363-ecd71aeb1257).html
https://biblio.vub.ac.be/vubir/immunemediated-type-1-diabetes-presenting-before-age-15-years-lack-of-relation-between-hla-dq-genotypes-and-clinical-disease-phenotype(0057d659-6d61-47ac-b363-ecd71aeb1257).html
Publikováno v:
Vrije Universiteit Brussel
Nutrient homeostasis is known to be regulated by pancreatic islet tissue. The function of islet beta-cells is controlled by a glucose sensor that operates at physiological glucose concentrations and acts in synergy with signals that integrate message
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::52e59499ab0e5bd70e48a7b69a7e92af
https://biblio.vub.ac.be/vubir/glucose-sensing-in-pancreatic-betacells-a-model-for-the-study-of-other-glucoseregulated-cells-in-gut-pancreas-and-hypothalamus-review(5b262bd7-2589-4911-8d0a-f8f1164054d7).html
https://biblio.vub.ac.be/vubir/glucose-sensing-in-pancreatic-betacells-a-model-for-the-study-of-other-glucoseregulated-cells-in-gut-pancreas-and-hypothalamus-review(5b262bd7-2589-4911-8d0a-f8f1164054d7).html
Publikováno v:
Vrije Universiteit Brussel
xxx
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::32c0698f1174d75584aef77ce16b1d98
https://biblio.vub.ac.be/vubir/relative-and-absolute-hla-dqa1dqb1linked-risk-for-developing-type-1-diabetes-before-age-40-years-in-the-belgian-population-implications-for-future-prevention-studies(d9ee2520-4bb9-49ba-85e1-dd04b0ef7aae).html
https://biblio.vub.ac.be/vubir/relative-and-absolute-hla-dqa1dqb1linked-risk-for-developing-type-1-diabetes-before-age-40-years-in-the-belgian-population-implications-for-future-prevention-studies(d9ee2520-4bb9-49ba-85e1-dd04b0ef7aae).html
Autor:
Yasmeeni Zambre, Zhidong Ling, Christiaan Van Schravendijk, Franciscus Schuit, Daniel Pipeleers, Decio Eizirik
Publikováno v:
Vrije Universiteit Brussel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2a3ebd26b87f183a1d957dbd6693824d
https://hdl.handle.net/20.500.14017/61644ede-babd-40eb-a73d-fe62c1f70c3c
https://hdl.handle.net/20.500.14017/61644ede-babd-40eb-a73d-fe62c1f70c3c
Publikováno v:
Vrije Universiteit Brussel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e94010a8d78b6e5c9b2d6fb89de3da42
https://hdl.handle.net/20.500.14017/2fd2cfac-1319-40a1-bf16-c4ceec7d3813
https://hdl.handle.net/20.500.14017/2fd2cfac-1319-40a1-bf16-c4ceec7d3813
Publikováno v:
Vrije Universiteit Brussel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::fdf70e5d78f1cb7704b48da744a6a076
Publikováno v:
Vrije Universiteit Brussel
Glucose metabolism by pancreatic beta and alpha cells is essential for stimulation of insulin secretion and inhibition of glucagon secretion. Studies using rodent islets have suggested that the ATP/ADP ratio serves as second messenger in beta cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::09e1a7b7e8db4a4105d9240cd7f30926
https://hdl.handle.net/20.500.14017/a38de73f-c7c8-4850-b717-7d8e1506302b
https://hdl.handle.net/20.500.14017/a38de73f-c7c8-4850-b717-7d8e1506302b