Výsledky vyhledávání - "Francisco de la Poza"

Akademický článek

Ns1 is a key protein in the vaccine composition to protect Ifnar(-/-) mice against infection with multiple serotypes of African horse sickness virus.

Autor: Francisco de la Poza, Eva Calvo-Pinilla, Elena López-Gil, Alejandro Marín-López, Francisco Mateos, Javier Castillo-Olivares, Gema Lorenzo, Javier Ortego

Publikováno v: PLoS ONE, Vol 8, Iss 7, p e70197 (2013)

African horse sickness virus (AHSV) belongs to the genus Orbivirus. We have now engineered naked DNAs and recombinant modified vaccinia virus Ankara (rMVA) expressing VP2 and NS1 proteins from AHSV-4. IFNAR((-/-)) mice inoculated with DNA/rMVA-VP2,-N

Externí odkaz: https://doaj.org/article/2b676491ffcf4903887c7b5bd9f4decb

Zobrazit plný text záznamu

Identification of CD8 T cell epitopes in VP2 and NS1 proteins of African horse sickness virus in IFNAR(-/-) mice

Autor: Alejandro Marín-López, Francisco de la Poza, Eva Calvo-Pinilla, Javier Castillo-Olivares, Javier Ortego

Publikováno v: Repositorio de Resultados de Investigación del INIA
INIA: Repositorio de Resultados de Investigación del INIA
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA

African horse sickness virus (AHSV) is an Orbivirus of the family Reoviridae that causes severe pathology in equids. Previous work in our laboratory showed the presence of AHSV-specific CD8+ T cells in mice immunized with recombinant Modified Vaccini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f277c8fbe4d52ed56418fd6b84a18e4
http://hdl.handle.net/20.500.12792/6091

Zobrazit plný text záznamu

VP2, VP7, and NS1 proteins of bluetongue virus targeted in avian reovirus muNS-Mi microspheres elicit a protective immune response in IFNAR(-/-) mice

Autor: Javier Ortego, Iria Otero-Romero, Francisco de la Poza, Alejandro Marín-López, José Martínez-Costas, Eva Calvo-Pinilla, Javier Benavente, Rebeca Menaya-Vargas

Vaccination is critical for controlling the spread of bluetongue virus (BTV). The inactivated BTV vaccines that are now being used in Europe are effective in preventing outbreaks of BTV but secondary effects associated to repetitive inoculation of al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a0d759f28f2b8cecff49b648febdc0e
https://pubmed.ncbi.nlm.nih.gov/25057758

Zobrazit plný text záznamu

Recombinant vaccines against bluetongue virus

Autor: Tamara Jabbar, Alejandro Marín-López, Javier Ortego, Francisco de la Poza, Javier Castillo-Olivares, Eva Calvo-Pinilla

Publikováno v: Repositorio de Resultados de Investigación del INIA
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA
INIA: Repositorio de Resultados de Investigación del INIA

Bluetongue (BT) is a hemorrhagic disease of ruminants caused by bluetongue virus (BTV), the prototype member of the genus Orbivirus within the family Reoviridae and is transmitted via biting midges of the genus Culicoides. BTV can be found on all con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::067b8093b5128debfc90ec2ddf8423cd
http://hdl.handle.net/20.500.12792/5590

Zobrazit plný text záznamu

Interferon α/β receptor knockout mice as a model to study bluetongue virus infection

Autor: Alejandro Marín-López, Francisco de la Poza, Javier Ortego

Bluetongue is an arthropod-borne disease caused by a virus of the genus Orbivirus, the bluetongue virus (BTV), which affects ruminant livestock such as cattle, sheep, and goats and wild ruminants such as deer, and camelids. Recently, adult mice with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::937232c49bed5741cf1105be1242cfb5

Zobrazit plný text záznamu

Ns1 Is a Key Protein in the Vaccine Composition to Protect Ifnar(−/−) Mice against Infection with Multiple Serotypes of African Horse Sickness Virus

Autor: Gema Lorenzo, Francisco de la Poza, Francisco Mateos, Javier Ortego, Elena López-Gil, Alejandro Marín-López, Eva Calvo-Pinilla, Javier Castillo-Olivares

Publikováno v: PLoS ONE
Repositorio de Resultados de Investigación del INIA
Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria INIA
INIA: Repositorio de Resultados de Investigación del INIA
PLoS ONE, Vol 8, Iss 7, p e70197 (2013)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7f0702577a7d0b3e0e25c874c45cd59
http://europepmc.org/articles/PMC3720900

Zobrazit plný text záznamu

Antiserum from mice vaccinated with modified vaccinia Ankara virus expressing African horse sickness virus (AHSV) VP2 provides protection when it is administered 48h before, or 48h after challenge

Autor: Peter P. C. Mertens, Francisco de la Poza, Javier Ortego, Simon Gubbins, Eva Calvo-Pinilla, Javier Castillo-Olivares

Highlights • Passive immunisation studies were conducted in IFNAR −/− mice using splenocytes and antiserum from donors. • Donors were immunised with modified vaccinia Ankara (MVA) expressing African horse sickness virus (AHSV) VP2. • After

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f5e39bea1886681ccd43f26c7c7dc81

Zobrazit plný text záznamu

Vaccination of mice with a modified Vaccinia Ankara (MVA) virus expressing the African horse sickness virus (AHSV) capsid protein VP2 induces virus neutralising antibodies that confer protection against AHSV upon passive immunisation

Autor: Simon Gubbins, Javier Castillo-Olivares, Eva Calvo-Pinilla, Peter P. C. Mertens, Francisco de la Poza, Javier Ortego

In previous studies we showed that a recombinant Modified Vaccinia Ankara (MVA) virus expressing the protein VP2 of AHSV serotype 4 (MVA-VP2) induced virus neutralising antibodies in horses and protected interferon alpha receptor gene knock-out mice

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a21e95220993bea0ea788ea840489081

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání