Zobrazeno 1 - 10 of 167 pro vyhledávání: '"Francisco Zafra"'
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A non-targeted metabolomic strategy for characterization of the botanical origin of honey samples using headspace gas chromatography—ion mobility spectrometry
Autor: Natalia Arroyo-Manzanares, María García-Nicolás, Francisco Zafra-Navarro, Natalia Campillo, Pilar Viñas
Publikováno v: Analytical Methods. 14:5047-5055
In this work, characterization of the botanical origin of honey was carried out using headspace gas chromatography coupled to ion mobility spectrometry (HS-GC-IMS). The proposed methodology was applied for the analysis of 89 samples from ten differen
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0c7ba31f1db869161417eb648135ed0
https://doi.org/10.1039/d2ay01479c
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4
Regulation of the Glycine Transporter GLYT1 by microRNAs
Autor: Francisco Zafra, Cecilio Giménez, Dolores Piniella, Esperanza Jiménez
Publikováno v: Neurochemical Research. 47:138-147
The glycine transporter GLYT1 participates in inhibitory and excitatory neurotransmission by controlling the reuptake of this neuroactive substance from synapses. Over the past few years, microRNAs have emerged as potent negative regulators of gene e
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4fde02dfb0b498a956ef0b1f648e95cd
https://doi.org/10.1007/s11064-021-03228-x
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5
Experimental and Bioinformatic Insights into the Effects of Epileptogenic Variants on the Function and Trafficking of the GABA Transporter GAT-1
Autor: Dolores Piniella, Ania Canseco, Silvia Vidal, Clara Xiol, Aránzazu Díaz de Bustamante, Itxaso Martí-Carrera, Judith Armstrong, Ugo Bastolla, Francisco Zafra
Publikováno v: International Journal of Molecular Sciences; Volume 24; Issue 2; Pages: 955
In this article, we identified a novel epileptogenic variant (G307R) of the gene SLC6A1, which encodes the GABA transporter GAT-1. Our main goal was to investigate the pathogenic mechanisms of this variant, located near the neurotransmitter permeatio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::953b99081294605c83e7c41df3bb05c4
https://doi.org/10.3390/ijms24020955
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6
Proximity labeling methods for proteomic analysis of membrane proteins
Autor: Dolores Piniella, Francisco Zafra
Publikováno v: Journal of proteomics. 264
Membrane proteins constitute the filter that controls the cellular traffic of nutrients, ions and other essential molecules, as well as the transmission of signals across the membrane. These proteins interact with other proteins in the cytosol, cytos
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5014fb06e989e1026a0a1780f028b036
https://pubmed.ncbi.nlm.nih.gov/35598870
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7
Identification by proximity labeling of novel lipidic and proteinaceous potential partners of the dopamine transporter
Autor: Elena Martínez-Blanco, David Bartolomé-Martín, Ana B Sanz-Martos, Dolores Piniella, Francisco Zafra
Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Cellular and Molecular Life Sciences
Biblos-e Archivo. Repositorio Institucional de la UAM
Dopamine (DA) transporters (DATs) are regulated by trafficking and modulatory processes that probably rely on stable and transient interactions with neighboring proteins and lipids. Using proximity-dependent biotin identification (BioID), we found no
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9192f2ed1c889d9aa6cff35d56b008e5
https://doi.org/10.1007/s00018-021-03998-1
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8
Activity dependent internalization of the glutamate transporter GLT-1 requires calcium entry through the NCX sodium/calcium exchanger
Autor: Francisco Zafra, Ignacio Ibáñez, David Bartolomé-Martín, Cecilio Giménez, Dolores Piniella
Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
GLT-1 is the main glutamate transporter in the brain and its trafficking controls its availability at the cell surface, thereby shaping glutamatergic neurotransmission under physiological and pathological conditions. Extracellular glutamate is known
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::807a16287019b7a337718215672cf3d1
https://doi.org/10.1016/j.neuint.2018.03.012
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9
Microglia and Inhibitory Circuitry in the Medullary Dorsal Horn: Laminar and Time-Dependent Changes in a Trigeminal Model of Neuropathic Pain
Autor: Nuria García-Magro, Pilar Negredo, Yasmina B. Martin, Carlos Avendaño, Francisco Zafra
Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 4564, p 4564 (2021)
International Journal of Molecular Sciences
Digital.CSIC. Repositorio Institucional del CSIC
instname
DDFV: Repositorio Institucional de la Universidad Francisco de Vitoria
Universidad Francisco de Vitoria
Volume 22
Issue 9
DDFV. Repositorio Institucional de la Universidad Francisco de Vitoria
Biblos-e Archivo. Repositorio Institucional de la UAM
Craniofacial neuropathic pain affects millions of people worldwide and is often difficult to treat. Two key mechanisms underlying this condition are a loss of the negative control exerted by inhibitory interneurons and an early microglial reaction. B
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d943f384bf7691e4e5fe849941efaa7
https://www.mdpi.com/1422-0067/22/9/4564
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