Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Francisco Victorino"'
Autor:
Francisco Victorino, Tarin M Bigley, Eugene Park, Cong-Hui Yao, Jeanne Benoit, Li-Ping Yang, Sytse J Piersma, Elvin J Lauron, Rebecca M Davidson, Gary J Patti, Wayne M Yokoyama
Publikováno v:
eLife, Vol 10 (2021)
Natural killer (NK) cells are essential for early protection against virus infection and must metabolically adapt to the energy demands of activation. Here, we found upregulation of the metabolic adaptor hypoxia-inducible factor-1α (HIF1α) is a fea
Externí odkaz:
https://doaj.org/article/3e3a62a1b135404db887eff1f946aea3
Autor:
Bennett Davenport, Jens Eberlein, Tom T Nguyen, Francisco Victorino, Kevin Jhun, Haedar Abuirqeba, Verena van der Heide, Peter Heeger, Dirk Homann
Publikováno v:
PLoS Pathogens, Vol 15, Iss 11, p e1008144 (2019)
The determinants of protective CD8+ memory T cell (CD8+TM) immunity remain incompletely defined and may in fact constitute an evolving agency as aging CD8+TM progressively acquire enhanced rather than impaired recall capacities. Here, we show that ol
Externí odkaz:
https://doaj.org/article/7f44a41999e049b080d7ca29466e1d46
Autor:
Steven K Hildemann, Jens Eberlein, Bennett Davenport, Tom T Nguyen, Francisco Victorino, Dirk Homann
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60420 (2013)
The destruction of infected cells by cytotxic T lymphocytes (CTL) is integral to the effective control of viral and bacterial diseases, and CTL function at large has long been regarded as a distinctive property of the CD8(+)T cell subset. In contrast
Externí odkaz:
https://doaj.org/article/73f7365e3a8343b5ad1d6f8745b79052
Autor:
Maxim V. Kuleshov, Francisco Victorino, Verena van der Heide, Ross M. Kedl, Jens Eberlein, Bennett Davenport, Avi Ma'ayan, Tom T Nguyen, Dirk Homann
Publikováno v:
J Immunol
Pathogen-specific memory T cells (TM) contribute to enhanced immune protection under conditions of reinfection, and their effective recruitment into a recall response relies, in part, on cues imparted by chemokines that coordinate their spatiotempora
Autor:
Tarin M. Bigley, Liping Yang, Liang-I Kang, Jose B. Saenz, Francisco Victorino, Wayne M. Yokoyama
Publikováno v:
Journal of Experimental Medicine. 219
Infections with herpesviruses, including human roseoloviruses, have been proposed to cause autoimmune disease, but defining a causal relationship and mechanism has been difficult due to the ubiquitous nature of infection and development of autoimmuni
Autor:
Sytse J. Piersma, Rebecca M. Davidson, Jeanne Benoit, Gary J. Patti, Eugene Park, Wayne M. Yokoyama, Elvin J. Lauron, Francisco Victorino, Tarin M Bigley, Liping Yang, Cong-Hui Yao
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Natural killer (NK) cells are essential for early protection against virus infection and must metabolically adapt to the energy demands of activation. Here, we found upregulation of the metabolic adaptor hypoxia-inducible factor-1α (HIF1α) is a fea
Autor:
Wayne M. Yokoyama, Francisco Victorino, Jeanne Benoit, Liping Yang, Cong-Hui Yao, Eugene Park, Sytse J. Piersma, Rebecca M. Davidson, Elvin J. Lauron, Tarin M Bigley, Gary J. Patti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4deb0c3f984bde1eaf016252ebb71eee
https://doi.org/10.7554/elife.68484.sa2
https://doi.org/10.7554/elife.68484.sa2
Autor:
Wayne M. Yokoyama, Ian B. Harvey, Michael D. Bern, Michael A. Paley, Graham D. Williams, Liping Yang, Francisco Victorino, Dorothy K. Sojka, Adrianus C. M. Boon, Eugene Park, Elvin J. Lauron
Publikováno v:
The Journal of Experimental Medicine
Lauron et al. demonstrate that viral MHCI inhibition within infected cells reduces local antigen-driven generation of resident memory CD8+ T cells. Additionally, resident memory CD8+ T cells are insufficient in controlling peripheral infection in the
Autor:
Wayne M. Yokoyama, Rebecca M. Davidson, Gary J. Patti, Yao C, Jeanne Benoit, Francisco Victorino, Sytse J. Piersma, Eugene Park, Elvin J. Lauron, Tarin M Bigley, Lu M. Yang
Natural killer (NK) cells are essential for early protection against virus infection, and must metabolically adapt to the energy demands of activation. Here, we found upregulation of the metabolic adaptor hypoxia inducible factor-1α (HIF-1α) is a f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1225a756824936111a5b5cd995094a32
https://doi.org/10.1101/2021.03.17.435833
https://doi.org/10.1101/2021.03.17.435833
Publikováno v:
Gastroenterology. 162:S-41