Superior metabolic improvement of polycystic ovary syndrome traits after GLP1-based multi-agonist therapy

Autor: Miguel A. Sánchez-Garrido, Víctor Serrano-López, Francisco Ruiz-Pino, María Jesús Vázquez, Andrea Rodríguez-Martín, Encarnación Torres, Inmaculada Velasco, Ana Belén Rodríguez, Eduardo Chicano-Gálvez, Marina Mora-Ortiz, Claes Ohlsson, Matti Poutanen, Leonor Pinilla, Francisco Gaytán, Jonathan D. Douros, Bin Yang, Timo D. Müller, Richard D. DiMarchi, Matthias H. Tschöp, Brian Finan, Manuel Tena-Sempere

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)

Abstract Polycystic ovary syndrome (PCOS) is a heterogeneous condition, defined by oligo-/anovulation, hyper-androgenism and/or polycystic ovaries. Metabolic complications are common in patients suffering PCOS, including obesity, insulin resistance a

Externí odkaz: https://doaj.org/article/e9aa6128690c4c71b7909dd30b6ade0a

Novel risk loci for COVID-19 hospitalization among admixed American populations

Autor: Silvia Diz-de Almeida, Raquel Cruz, Andre D Luchessi, José M Lorenzo-Salazar, Miguel López de Heredia, Inés Quintela, Rafaela González-Montelongo, Vivian Nogueira Silbiger, Marta Sevilla Porras, Jair Antonio Tenorio Castaño, Julian Nevado, Jose María Aguado, Carlos Aguilar, Sergio Aguilera-Albesa, Virginia Almadana, Berta Almoguera, Nuria Alvarez, Álvaro Andreu-Bernabeu, Eunate Arana-Arri, Celso Arango, María J Arranz, Maria-Jesus Artiga, Raúl C Baptista-Rosas, María Barreda- Sánchez, Moncef Belhassen-Garcia, Joao F Bezerra, Marcos AC Bezerra, Lucía Boix-Palop, María Brion, Ramón Brugada, Matilde Bustos, Enrique J Calderón, Cristina Carbonell, Luis Castano, Jose E Castelao, Rosa Conde-Vicente, M Lourdes Cordero-Lorenzana, Jose L Cortes-Sanchez, Marta Corton, M Teresa Darnaude, Alba De Martino-Rodríguez, Victor del Campo-Pérez, Aranzazu Diaz de Bustamante, Elena Domínguez-Garrido, Rocío Eirós, María Carmen Fariñas, María J Fernandez-Nestosa, Uxía Fernández-Robelo, Amanda Fernández-Rodríguez, Tania Fernández-Villa, Manuela Gago-Dominguez, Belén Gil-Fournier, Javier Gómez-Arrue, Beatriz González Álvarez, Fernan Gonzalez Bernaldo de Quirós, Anna González-Neira, Javier González-Peñas, Juan F Gutiérrez-Bautista, María José Herrero, Antonio Herrero-Gonzalez, María A Jimenez-Sousa, María Claudia Lattig, Anabel Liger Borja, Rosario Lopez-Rodriguez, Esther Mancebo, Caridad Martín-López, Vicente Martín, Oscar Martinez-Nieto, Iciar Martinez-Lopez, Michel F Martinez-Resendez, Angel Martinez-Perez, Juliana F Mazzeu, Eleuterio Merayo Macías, Pablo Minguez, Victor Moreno Cuerda, Silviene F Oliveira, Eva Ortega-Paino, Mara Parellada, Estela Paz-Artal, Ney PC Santos, Patricia Pérez-Matute, Patricia Perez, M Elena Pérez-Tomás, Teresa Perucho, Mellina Pinsach-Abuin, Guillermo Pita, Ericka N Pompa-Mera, Gloria L Porras-Hurtado, Aurora Pujol, Soraya Ramiro León, Salvador Resino, Marianne R Fernandes, Emilio Rodríguez-Ruiz, Fernando Rodriguez-Artalejo, José A Rodriguez-Garcia, Francisco Ruiz-Cabello, Javier Ruiz-Hornillos, Pablo Ryan, José Manuel Soria, Juan Carlos Souto, Eduardo Tamayo, Alvaro Tamayo-Velasco, Juan Carlos Taracido-Fernandez, Alejandro Teper, Lilian Torres-Tobar, Miguel Urioste, Juan Valencia-Ramos, Zuleima Yáñez, Ruth Zarate, Itziar de Rojas, Agustín Ruiz, Pascual Sánchez, Luis Miguel Real, SCOURGE Cohort Group, Encarna Guillen-Navarro, Carmen Ayuso, Esteban Parra, José A Riancho, Augusto Rojas-Martinez, Carlos Flores, Pablo Lapunzina, Ángel Carracedo

Publikováno v: eLife, Vol 13 (2024)

The genetic basis of severe COVID-19 has been thoroughly studied, and many genetic risk factors shared between populations have been identified. However, reduced sample sizes from non-European groups have limited the discovery of population-specific

Externí odkaz: https://doaj.org/article/011994bb968f4b9ab2fc855d5fdf6178

Formation mechanisms and environmental influences on the crystal growth of wulfenite

Autor: Nik Gračanin, Matejka Podlogar, Sorour Semsari Parapari, Pascal Boulet, Francisco Ruiz-Zepeda, Sašo Šturm, Nastja Rogan Šmuc

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)

Abstract In this study, we introduce a novel approach using correlative analysis techniques to unravel detailed insights into the environmental influences on crystal growth. Tabular and bipyramidal wulfenite samples from the Mežica mine in north-eas

Externí odkaz: https://doaj.org/article/c70bf7ef1fab4b46a5adc8e2176cab21

Publisher Correction: Formation mechanisms and environmental influences on the crystal growth of wulfenite

Autor: Nik Gračanin, Matejka Podlogar, Sorour Semsari Parapari, Pascal Boulet, Francisco Ruiz-Zepeda, Sašo Šturm, Nastja Rogan Šmuc

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-3 (2024)

Externí odkaz: https://doaj.org/article/bf66e044729c4cdaa5c655969d4cf8dc

Mapping the risk of exposure to Crimean-Congo haemorrhagic fever virus in the Iberian Peninsula using Eurasian wild boar (Sus scrofa) as a model

Autor: Sara Baz-Flores, Cesar Herraiz, Alfonso Peralbo-Moreno, Marta Barral, Mari Cruz Arnal, Ana Balseiro, David Cano-Terriza, Sabrina Castro-Scholten, Aitor Cevidanes, Alazne Conde-Lizarralde, Raúl Cuadrado-Matías, Fernando Escribano, Daniel Fernández de Luco, Luis Eusebio Fidalgo, Javier Hermoso-de Mendoza, Paulino Fandos, Félix Gómez-Guillamón, José E. Granados, Débora Jiménez-Martín, Jorge R. López-Olvera, Inés Martín, Remigio Martínez, Gregorio Mentaberre, Ignacio García-Bocanegra, Francisco Ruiz-Fons

Publikováno v: Ticks and Tick-Borne Diseases, Vol 15, Iss 1, Pp 102281- (2024)

Crimean-Congo haemorrhagic fever (CCHF) virus (CCHFV) is a tick-borne zoonotic pathogen that can cause a lethal haemorrhagic disease in humans. Although the virus appears to be endemically established in the Iberian Peninsula, CCHF is an emerging dis

Externí odkaz: https://doaj.org/article/97d16c4dd44a47d2ba7b2b85f6f282bc