Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Francisco R. M. Laurindo"'
Autor:
Leonardo Y. Tanaka, Sandeep Kumar, Lucas F. Gutierre, Celso Magnun, Daniela Kajihara, Dong-Won Kang, Francisco R. M. Laurindo, Hanjoong Jo
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Redox processes can modulate vascular pathophysiology. The endoplasmic reticulum redox chaperone protein disulfide isomerase A1 (PDIA1) is overexpressed during vascular proliferative diseases, regulating thrombus formation, endoplasmic reticulum stre
Externí odkaz:
https://doaj.org/article/d94ab7f322dd461c80bc666ed3c3e66e
Autor:
Daniela Kajihara, Chung-Chau Hon, Aimi Naim Abdullah, João Wosniak, Ana Iochabel S. Moretti, Joice F. Poloni, Diego Bonatto, Kosuke Hashimoto, Piero Carninci, Francisco R. M. Laurindo
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-16 (2020)
Abstract Background Protein Disulfide Isomerases are thiol oxidoreductase chaperones from thioredoxin superfamily with crucial roles in endoplasmic reticulum proteostasis, implicated in many diseases. The family prototype PDIA1 is also involved in va
Externí odkaz:
https://doaj.org/article/03a26eaff3a348368fb6dcc6966203e0
Autor:
Ana I. S. Moretti, Jessyca C. Pavanelli, Patrícia Nolasco, Matthias S. Leisegang, Leonardo Y. Tanaka, Carolina G. Fernandes, João Wosniak, Daniela Kajihara, Matheus H. Dias, Denise C. Fernandes, Hanjoong Jo, Ngoc-Vinh Tran, Ingo Ebersberger, Ralf P. Brandes, Diego Bonatto, Francisco R. M. Laurindo
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-18 (2017)
Abstract Protein disulfide isomerases (PDIs) support endoplasmic reticulum redox protein folding and cell-surface thiol-redox control of thrombosis and vascular remodeling. The family prototype PDIA1 regulates NADPH oxidase signaling and cytoskeleton
Externí odkaz:
https://doaj.org/article/ecacaa9b61b844f7b39828427de7b836
Autor:
Fabiana Henriques Machado de Melo, Diego Assis Gonçalves, Ricardo Xisto de Sousa, Marcelo Yudi Icimoto, Denise de Castro Fernandes, Francisco R. M. Laurindo, Miriam Galvonas Jasiulionis
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9556 (2021)
Melanoma is the most aggressive type of skin cancer due to its high capability of developing metastasis and acquiring chemoresistance. Altered redox homeostasis induced by increased reactive oxygen species is associated with melanomagenesis through m
Externí odkaz:
https://doaj.org/article/de23ef06a2af48ea8351857bae344bbb
Autor:
Jessica L. O. Campos, Tabata R. Doratioto, Natalia B. Videira, Helder V. Ribeiro Filho, Fernanda A. H. Batista, Juliana Fattori, Nathalia de C. Indolfo, Marcel Nakahira, Marcio C. Bajgelman, Aleksandra Cvoro, Francisco R. M. Laurindo, Paul Webb, Ana Carolina M. Figueira
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2019)
Thyroid hormone receptors (TRs) are responsible for mediating thyroid hormone (T3 and T4) actions at a cellular level. They belong to the nuclear receptor (NR) superfamily and execute their main functions inside the cell nuclei as hormone-regulated t
Externí odkaz:
https://doaj.org/article/7be8a6b634b941de8090e0b4ae62c3fb
Autor:
Karina Cristina Giannotti, Sönke Weinert, Mariana Nascimento Viana, Elbio Leiguez, Thaís L. S. Araujo, Francisco R. M. Laurindo, Bruno Lomonte, Rüdiger Braun-Dullaeus, Catarina Teixeira
Publikováno v:
Molecules, Vol 24, Iss 18, p 3244 (2019)
Vascular smooth muscle cells (VSMCs) loaded with lipid droplets (LDs) are markers of atherosclerosis. In this disease, inflammatory Group IIA-secreted phospholipase A2s (GIIA sPLA2s) are highly expressed in VSMCs, but their actions in these cells are
Externí odkaz:
https://doaj.org/article/2195ed3b883848a7b81fabe1db58f33f
Autor:
Beatriz S. Stolf, Ioannis Smyrnias, Lucia R. Lopes, Alcione Vendramin, Hiro Goto, Francisco R. M. Laurindo, Ajay M. Shah, Celio X. C. Santos
Publikováno v:
The Scientific World Journal, Vol 11, Pp 1749-1761 (2011)
Reactive oxygen species (ROS) production by immunological cells is known to cause damage to pathogens. Increasing evidence accumulated in the last decade has shown, however, that ROS (and redox signals) functionally regulate different cellular pathwa
Externí odkaz:
https://doaj.org/article/8aeb7bc3d65c4b82b06aefbed6948c70
Autor:
Jose Henrique M. Oliveira, Renata L. S. Gonçalves, Flavio A. Lara, Felipe A. Dias, Ana Caroline P. Gandara, Rubem F. S. Menna-Barreto, Meredith C. Edwards, Francisco R. M. Laurindo, Mário A. C. Silva-Neto, Marcos H. F. Sorgine, Pedro L. Oliveira
Publikováno v:
PLoS Pathogens, Vol 9, Iss 2 (2013)
Externí odkaz:
https://doaj.org/article/22e65e01beea4821b574c77c0048498e
Autor:
Francisco R. M. Laurindo
Publikováno v:
Arquivos Brasileiros de Cardiologia, Vol 110, Iss 1, Pp 5-6
Externí odkaz:
https://doaj.org/article/d2321d26481b434bb1de42f2e8e25e3b
Publikováno v:
Clinical science (London, England : 1979). 132(10)
Cardiac hypertrophy (CH) is a major independent risk factor for heart failure and mortality. However, therapeutic interventions that target hypertrophy signaling in a load-independent way are unavailable. In a recent issue of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7ac3ac22a0512eeb3cb573ad6678618b
https://pubmed.ncbi.nlm.nih.gov/29540538
https://pubmed.ncbi.nlm.nih.gov/29540538