Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Francisco Olivares-Silva"'
Autor:
Samir Bolívar, Renatto Anfossi, Claudio Humeres, Raúl Vivar, Pía Boza, Claudia Muñoz, Viviana Pardo-Jimenez, Francisco Olivares-Silva, Guillermo Díaz-Araya
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Cardiac fibroblasts (CFs) contribute to theinflammatory response to tissue damage, secreting both pro- and anti-inflammatory cytokines and chemokines. Interferon beta (IFN-β) induces the phosphorylation of signal transducer and activator of transcri
Externí odkaz:
https://doaj.org/article/a94bb2cf49204d6a897d332ae9ee6d15
Autor:
Jenaro A. Espitia-Corredor, Licia Shamoon, Francisco Olivares-Silva, Constanza Rimassa-Taré, Claudia Muñoz-Rodríguez, Claudio Espinoza-Pérez, Carlos F. Sánchez-Ferrer, Concepción Peiró, Guillermo Díaz-Araya
Publikováno v:
Biblos-e Archivo. Repositorio Institucional de la UAM
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Cardiac fibroblasts (CFs) undergo senescence in reaction to different stressors, leading to a poor prognosis of cardiac disease. Doxorubicin (Doxo) is an antineoplastic drug with strong cardiotoxic effects, which induces IL-1β secretion and thus, tr
Autor:
Guillermo Díaz-Araya, Viviana Pardo-Jiménez, Alan Letelier, Francisco Olivares-Silva, Ivonne Olmedo, Jenaro Espitia-Corredor, Pablo Parra-Flores, Raúl Vivar, J. Montenegro
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 70
Transforming growth factor-beta 1 (TGF-β1) is a cytokine with marked pro-fibrotic action on cardiac fibroblasts (CF). TGF-β1 induces CF-to-cardiac myofibroblast (CMF) differentiation, defined by an increase in α-smooth muscle cells (α-SMA), colla
Autor:
Pablo Aránguiz, Francisco Olivares-Silva, Concepción Peiró, Claudia Muñoz, Carlos F. Sánchez-Ferrer, Samir Bolivar, Pía Boza, Claudio Humeres, Viviana Pardo-Jiménez, Rodolfo Landaeta, Raúl Vivar, Renatto Anfossi, Guillermo Díaz-Araya
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1864:831-842
Cardiac fibroblasts (CF) act as sentinel cells responding to chemokines, cytokines and growth factors released in cardiac tissue in cardiac injury events, such as myocardial infarction (MI). Cardiac injury involves the release of various damage-assoc
Autor:
José Miguel Osorio, Francisco Olivares-Silva, David Silva, Guillermo Díaz-Araya, Raúl Vivar, Nicole De Gregorio, Jenaro Espitia-Corredor, Claudio Espinoza, Concepción Peiró, Sergio Lavandero, Carlos F. Sánchez-Ferrer
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1867:166241
Aims Despite the broad pharmacological arsenal to treat hypertension, chronic patients may develop irreversible cardiac remodeling and fibrosis. Angiotensin II, the main peptide responsible for the Renin-Angiotensin-Aldosterone-System, has been close
Autor:
Raúl Vivar, Samir Bolivar, A. Salas-Hernández, P. Valenzuela, E. Castro, Viviana Pardo-Jiménez, Jenaro Espitia-Corredor, Francisco Olivares-Silva, Claudio Humeres, Renatto Anfossi, Guillermo Díaz-Araya
Publikováno v:
Cytokine. 138
Cardiac fibroblasts (CF) play a key role in the homeostasis of the extracellular matrix in cardiac tissue and are newly recognized as inflammatory supporter cells. Besides, CF-to-Cardiac myofibroblast differentiation is commanded by TGF-b, through SM
Autor:
Samir Bolivar, Guillermo Díaz-Araya, Raúl Vivar, Claudia Muñoz, José Miguel Osorio, Renatto Anfossi, Claudio Humeres, Francisco Olivares-Silva, Lorena García, Pía Boza
Publikováno v:
Journal of molecular and cellular cardiology.
Macrophage polarization plays an essential role in cardiac remodeling after injury, evolving from an initial accumulation of proinflammatory M1 macrophages to a greater balance of anti-inflammatory M2 macrophages. Whether cardiac fibroblasts themselv