Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Francisco Nualart"'
Publikováno v:
Molecular Metabolism, Vol 84, Iss , Pp 101940- (2024)
Objective: The liver releases glucose into the blood using the glucose-6-phosphatase (G6Pase) system, a multiprotein complex located in the endoplasmic reticulum (ER). Here, we show for the first time that the G6Pase system is also expressed in hypot
Externí odkaz:
https://doaj.org/article/cb4efdf820274c3a997f4de3d26ce64e
Publikováno v:
Cell Death and Disease, Vol 14, Iss 9, Pp 1-11 (2023)
Abstract Since the discovery of ferroptosis, it has been postulated that this type of cell death could be utilized in treatments for cancer. Unfortunately, several highly aggressive tumor models are resistant to the pharmacological induction of ferro
Externí odkaz:
https://doaj.org/article/be77b87de6be4aa69409aa256dc4bfcb
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S213- (2023)
Externí odkaz:
https://doaj.org/article/633a17cf277b4a9ebaf069bbddac9aac
Autor:
Francisco Nualart, Manuel Cifuentes, Eder Ramírez, Fernando Martínez, María José Barahona, Luciano Ferrada, Natalia Saldivia, Ernesto R Bongarzone, Bernard Thorens, Katterine Salazar
Publikováno v:
PLoS Biology, Vol 21, Iss 9, p e3002308 (2023)
Hyperglycemia increases glucose concentrations in the cerebrospinal fluid (CSF), activating glucose-sensing mechanisms and feeding behavior in the hypothalamus. Here, we discuss how hyperglycemia temporarily modifies ependymal cell ciliary beating to
Externí odkaz:
https://doaj.org/article/e8d20301a8f849e99297707a29ca665a
Autor:
Katterine Salazar, Nery Jara, Eder Ramírez, Isabelle de Lima, Javiera Smith-Ghigliotto, Valentina Muñoz, Luciano Ferrada, Francisco Nualart
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Different studies have established the fundamental role of vitamin C in proliferation, differentiation, and neurogenesis in embryonic and adult brains, as well as in in vitro cell models. To fulfill these functions, the cells of the nervous system re
Externí odkaz:
https://doaj.org/article/00f9a39165ff4208863d07271525b62d
Autor:
Victor Baeza, Manuel Cifuentes, Fernando Martínez, Eder Ramírez, Francisco Nualart, Luciano Ferrada, María José Oviedo, Isabelle De Lima, Ninoschka Troncoso, Natalia Saldivia, Katterine Salazar
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Ependymal cells have multiple apical cilia that line the ventricular surfaces and the central canal of spinal cord. In cancer, the loss of ependymal cell polarity promotes the formation of different types of tumors, such as supratentorial an
Externí odkaz:
https://doaj.org/article/ae82d70191ff4511854dc48d57c6fbe3
Autor:
Alejandra A. Latorre, Ricardo Oliva, Julio Pugin, Alexis Estay, Francisco Nualart, Katterine Salazar, Natacha Garrido, Marcos A. Muñoz
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Biofilms in milking equipment on dairy farms have been associated with failures in cleaning and sanitizing protocols. These biofilms on milking equipment can be a source of contamination for bulk tank milk and a concern for animal and public health,
Externí odkaz:
https://doaj.org/article/b94454c3bc62403c997fff880546462e
Autor:
Luciano Ferrada, María José Barahona, Katterine Salazar, Alejandro S. Godoy, Matias Vera, Francisco Nualart
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Neuroblastomas are the main extracranial tumors that affect children, while glioblastomas are the most lethal brain tumors, with a median survival time of less than 12 months, and the prognosis of these tumors is poor due to multidrug resistance. Thu
Externí odkaz:
https://doaj.org/article/d634bb71b0784f8a9acbe3066dc3c10a
Autor:
Nery Jara, Manuel Cifuentes, Fernando Martínez, Iván González-Chavarría, Katterine Salazar, Lucas Ferrada, Francisco Nualart
Publikováno v:
Antioxidants, Vol 11, Iss 10, p 2030 (2022)
Although scurvy, the severe form of vitamin C deficiency, has been almost eradicated, the prevalence of subclinical vitamin C deficiency is much higher than previously estimated and its impact on human health might not be fully understood. Vitamin C
Externí odkaz:
https://doaj.org/article/e3042f2c75d74f58babc3d9959ea34e8
Autor:
María José Oviedo, Eder Ramírez, Manuel Cifuentes, Carlos Farkas, Andy Mella, Romina Bertinat, Roberto Gajardo, Luciano Ferrada, Nery Jara, Isabelle De Lima, Fernando Martínez, Francisco Nualart, Katterine Salazar
Publikováno v:
Cells, Vol 11, Iss 20, p 3327 (2022)
The identification of new proteins that regulate the function of one of the main cellular phosphatases, protein phosphatase 1 (PP1), is essential to find possible pharmacological targets to alter phosphatase function in various cellular processes, in
Externí odkaz:
https://doaj.org/article/f556566cb26d4a3ca86a433318a290b7