Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Francisco N, Newby"'
Structural Effects of Two Camelid Nanobodies Directed to Distinct C-Terminal Epitopes on a-Synuclein
Autor:
Farah El-Turk, Michele Vendruscolo, Tim Guilliams, Francisco N. Newby, Erwin De Genst, Christopher M. Dobson, Tara Sprules, Anthony Mittermaier
Publikováno v:
Biochemistry
α-Synuclein is an intrinsically disordered protein whose aggregation is associated with Parkinson's disease and other related neurodegenerative disorders. Recently, two single-domain camelid antibodies (nanobodies) were shown to bind α-synuclein wi
Autor:
Minkoo, Ahn, Christine L, Hagan, Ana, Bernardo-Gancedo, Erwin, De Genst, Francisco N, Newby, John, Christodoulou, Anne, Dhulesia, Mireille, Dumoulin, Carol V, Robinson, Christopher M, Dobson, Janet R, Kumita
Publikováno v:
Biophysical journal. 111(11)
The conversion of human lysozyme into amyloid fibrils is associated with a rare but fatal hereditary form of nonneuropathic systemic amyloidosis. The accumulation of large amounts of aggregated protein is thought to be initiated by the formation of t
Autor:
Alfonso De Simone, Christopher M. Dobson, Michele Vendruscolo, Maho Yagi-Utsumi, Francisco N. Newby, Xavier Salvatella
Residual dipolar couplings (RDCs) and paramagnetic relaxation enhancements (PREs) have emerged as valuable parameters for defining the structures and dynamics of disordered proteins by nuclear magnetic resonance (NMR) spectroscopy. Procedures for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4f8042ef6056cbb49050484d02ea9b3
http://hdl.handle.net/11588/839744
http://hdl.handle.net/11588/839744
Publikováno v:
Langmuir. 20:9124-9129
Aqueous solutions of alpha-cyclodextrin (alpha-CD) complex spontaneously with poly(ethylene oxide) (PEO), forming a supramolecular structure known as pseudopolyrotaxane. We have studied the formation of the complex obtained from the threading of alph
Publikováno v:
Chemistry of Materials. 18:598-600
Complex microparticles of the brookite polymorph of titania are produced for the first time by sol−gel replication of dandelion pollen grains in a nonaqueous medium.