Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Francisco Morales-Zavala"'
Autor:
Edison Salas-Huenuleo, Andrea Hernández, Lorena Lobos-González, Iva Polakovičová, Francisco Morales-Zavala, Eyleen Araya, Freddy Celis, Carmen Romero, Marcelo J. Kogan
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 958 (2022)
One of the recent attractive therapeutic approaches for cancer treatment is restoring downregulated microRNAs. They play an essential muti-regulatory role in cellular processes such as proliferation, differentiation, survival, apoptosis, cell cycle,
Externí odkaz:
https://doaj.org/article/1c0e329bbf6242a4a68af867a74680a2
Autor:
Francisco Morales-Zavala, Nathalie Casanova-Morales, Raúl B. Gonzalez, América Chandía-Cristi, Lisbell D. Estrada, Ignacio Alvizú, Victor Waselowski, Fanny Guzman, Simón Guerrero, Marisol Oyarzún-Olave, Cristian Rebolledo, Enrique Rodriguez, Julien Armijo, Heman Bhuyan, Mario Favre, Alejandra R. Alvarez, Marcelo J. Kogan, Jerónimo R. Maze
Publikováno v:
Journal of Nanobiotechnology, Vol 16, Iss 1, Pp 1-14 (2018)
Abstract Background Stable and non-toxic fluorescent markers are gaining attention in molecular diagnostics as powerful tools for enabling long and reliable biological studies. Such markers should not only have a long half-life under several assay co
Externí odkaz:
https://doaj.org/article/d5d9948034a34eb69432812892a2904a
Autor:
Pedro Jara-Guajardo, Pablo Cabrera, Freddy Celis, Mónica Soler, Isadora Berlanga, Nicole Parra-Muñoz, Gerardo Acosta, Fernando Albericio, Fanny Guzman, Marcelo Campos, Alejandra Alvarez, Francisco Morales-Zavala, Marcelo J Kogan
Publikováno v:
Nanomaterials, Vol 10, Iss 4, p 690 (2020)
The early detection of the amyloid beta peptide aggregates involved in Alzheimer’s disease is crucial to test new potential treatments. In this research, we improved the detection of amyloid beta peptide aggregates in vitro and ex vivo by fluoresce
Externí odkaz:
https://doaj.org/article/eadcecbc5fc741b5a06c194204f30c08
Autor:
Sujey Palma-Florez, Adrián López-Canosa, Francisco Morales-Zavala, Oscar Castaño, M.J. Kogan, Josep Samitier, Anna Lagunas, Mónica Mir
Background The lack of predictive models that mimic the blood–brain barrier (BBB) hinders the development of effective drugs for neurodegenerative diseases. Animal models behave differently from humans, are expensive and have ethical constraints. O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70b8ab9b0e2716b94ae301c6953df093
https://doi.org/10.1101/2022.09.05.505851
https://doi.org/10.1101/2022.09.05.505851
Autor:
David Chamorro, Gerardo A. Acosta, Ernest Giralt, Pedro Jara-Guajardo, Marcelo J. Kogan, Nicole Salgado, Ana Riveros, Fernando Albericio, Francisco Morales-Zavala, Paola Pismante, Eyleen Araya, Alejandra Alvarez R, Macarena Sánchez-Navarro, Rodrigo A. Vásquez, America Chandia-Cristi
Publikováno v:
Biomaterials Science. 9:4178-4190
The development and use of nanosystems is an emerging strategy for the diagnosis and treatment of a broad number of diseases, such as Alzheimer's disease (AD). Here, we developed a neurotheranostic nanosystem based on gold nanorods (GNRs) that works
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0ffa0f838012471f9730af938343a71
https://doi.org/10.1039/d0bm01825b
https://doi.org/10.1039/d0bm01825b
Autor:
Pablo Cabrera, Pedro Jara-Guajardo, María Paz Oyarzún, Nicole Parra-Muñoz, Aldo Campos, Mónica Soler, Alejandra Álvarez, Francisco Morales-Zavala, Eyleen Araya, Alicia N. Minniti, Rebeca Aldunate, Marcelo J. Kogan
Publikováno v:
Nanomedicine : nanotechnology, biology, and medicine. 44
The β-amyloid (Aβ) peptide is one of the key etiological agents in Alzheimer's disease (AD). The in vivo detection of Aβ species is challenging in all stages of the illness. Currently, the development of fluorescent probes allows the detection of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0064f14587ebd4cda655835a04c72839
https://pubmed.ncbi.nlm.nih.gov/35595016
https://pubmed.ncbi.nlm.nih.gov/35595016
Autor:
María Paz Ocaranza, Andrea Ramírez-Sagredo, Mario Chiong, Ana Riveros, Javier O. Morales, María Gabriela Villamizar Sarmiento, Aldo Rojas, Jaime A. Riquelme, Yvo Flores, Marcelo J. Kogan, Fanny Guzmán, Francisco Morales-Zavala, Eyleen Araya, Julian Bejarano, Gina Sánchez, Sergio Lavandero
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 328
Angiotensin-(1-9), a component of the non-canonical renin-angiotensin system, has a short half-life in blood. This peptide has shown to prevent and/or attenuate hypertension and cardiovascular remodeling. A controlled release of angiotensin-(1-9) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b670537df9934ec5f16430ba199b073
https://pubmed.ncbi.nlm.nih.gov/33160006
https://pubmed.ncbi.nlm.nih.gov/33160006
Autor:
Francisco Morales-Zavala, Eyleen Araya, J. Ruff, Julia Steitz, Ulrich Simon, Marcelo J. Kogan, Natalia Hassan
Publikováno v:
Journal of materials chemistry. B. 6(16)
Gold nanoparticles with specific optical properties in combination with the CLPFFD peptide that exhibits selectivity for β-amyloid (Aβ) aggregates are promising photothermal absorbers for application in Alzheimer's disease therapy. We report on hol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c15297d4d48847e91a49ee0126816d14
https://pubmed.ncbi.nlm.nih.gov/32254460
https://pubmed.ncbi.nlm.nih.gov/32254460
Autor:
Jeronimo R. Maze, Raúl González, Ignacio Alvizu, Cristian Rebolledo, Enrique Alcalde Rodríguez, Marisol Oyarzún-Olave, Alejandra R. Alvarez, America Chandia-Cristi, Marcelo J. Kogan, Lisbell D. Estrada, Francisco Morales-Zavala, Nathalie Casanova-Morales, Mario Favre, Victor Waselowski, Simón Guerrero, Julien Armijo, Fanny Guzmán, Heman Bhuyan
Publikováno v:
Journal of Nanobiotechnology, Vol 16, Iss 1, Pp 1-14 (2018)
Journal of Nanobiotechnology
Journal of Nanobiotechnology
Background Stable and non-toxic fluorescent markers are gaining attention in molecular diagnostics as powerful tools for enabling long and reliable biological studies. Such markers should not only have a long half-life under several assay conditions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2deab0303ab483de740d75c81ee2c62
http://link.springer.com/article/10.1186/s12951-018-0385-7
http://link.springer.com/article/10.1186/s12951-018-0385-7
Autor:
Pablo Castro, Javier O. Morales, Marcelo J. Kogan, Julian Bejarano, Yvo Flores, Francisco Morales-Zavala, Hugo Verdejo, Sergio Lavandero, Ivonne Garcia-Carvajal, Eyleen Araya-Fuentes, Mario Navarro-Marquez
Publikováno v:
Theranostics
Cardiovascular diseases are the leading cause of death worldwide. Despite preventive efforts, early detection of atherosclerosis, the common pathophysiological mechanism underlying cardiovascular diseases remains elusive, and overt coronary artery di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c151940d97ced02f9f23987e2dc59df
https://doi.org/10.7150/thno.26284
https://doi.org/10.7150/thno.26284