Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Francisco Martínez-Olid"'
Autor:
Nicholas S. Kirk, Qi Chen, Yingzhe Ginger Wu, Anastasia L. Asante, Haitao Hu, Juan F. Espinosa, Francisco Martínez-Olid, Mai B. Margetts, Faiz A. Mohammed, Vladislav V. Kiselyov, David G. Barrett, Michael C. Lawrence
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The regulation of plasma glucose levels is effected by insulin. Here, the authors reveal atomic detail of how peptides distinct from insulin bind to and activate the insulin receptor, with implications for design of small-molecule insulin mimetics.
Externí odkaz:
https://doaj.org/article/1dab09f8cbff49e29577a56810f3b259
Autor:
Santiago Cañellas, Jeffery Richardson, Gary Sharman, Francisco Martínez-Olid, Jose Enrique Gomez
Publikováno v:
Reaction Chemistry & Engineering. 5:779-792
An automated analysis pipeline is outlined that helps unlock the true potential of late stage functionalisation (LSF). LSF is an extremely powerful strategy, of increasing importance, for the rapid expansion and exploration of structure–activity re
Autor:
Leonard L. Winneroski, Dustin J. Mergott, Amy C. DeBaillie, Yuan Shi, Brian Morgan Watson, Francisco Martínez-Olid, Carolina Alhambra Jimenez, Mario Barberis, Chauncey D. Jones, Pablo Garcia-Losada, Erik James Hembre
Publikováno v:
Organic Process Research & Development. 22:650-654
Here we report an optimized protocol for the asymmetric introduction of a fluorine atom into a quaternary center facilitated by d-proline, Selectfluor®, and trifluoroethanol. The synthesis proceeds over four steps starting from a chiral amino alcoho
Autor:
Susana García-Cerrada, Pablo Garcia-Losada, Juan A. Rincón, Francisco Martínez-Olid, Laura Redondo-Gallego
Publikováno v:
Organic Process Research & Development. 21:779-784
The diastereoselective preparation of cis- or trans-4-substituted-4-aminocyclohexyl alcohols by conventional chemical processes reported in the literature requires long synthetic sequences and is not amenable to scale-up. In the past decade, ketoredu
Autor:
Juan C. Flores, Francisco Martínez-Olid, Pilar Gómez-Sal, Román Andrés, Karine Heuzé, Ernesto de Jesús, Luc Vellutini
Publikováno v:
Dalton Transactions. 45:11633-11638
Pre-synthesized mono- and bis(NHC) palladium complexes have been grafted onto magnetic core/shell γ-Fe2O3/silica particles and tested as catalysts in model Suzuki-Miyaura coupling reactions. The bis(NHC) immobilized complex was found to be a robust
Publikováno v:
European Journal of Inorganic Chemistry. 2015:4076-4087
A series of mono- and dendritic trimetallic PEPPSI-type (pyridine-enhanced precatalyst preparation stabilization and initiation) complexes bearing N-heterocyclic carbene (NHC) ligands containing a protected amine in the form of an ethylphthalimido gr
Publikováno v:
Inorganica Chimica Acta. 409:156-162
Iminopyridine ligands of general formula G n-PBE- ONN (G n-PBE = Frechet-type dendritic wedges of generation G0 ( 1 ), G1 ( 2 ), G2 ( 3 ), and G3 ( 4 ); – ONN = -O-4-(2,5-Me 2 C 6 H 2 )-N CH-2-py) have been prepared starting from H- ONN . Reaction
Publikováno v:
Israel Journal of Chemistry. 49:99-108
This overview covers the most relevant results obtained by our group in the last few years concerning the synthesis and catalytic applications of metal complexes anchored to the surface of carbosilane dendrimers functionalized with iminopyridine liga
Publikováno v:
ChemInform. 41