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pro vyhledávání: '"Francisco Manuel Reimunde"'
Autor:
Fernando Rodríguez-Pascual, Cristina Castañares, Mariano Redondo-Horcajo, Santiago Lamas, Francisco Manuel Reimunde
Publikováno v:
Biochemical Journal. 387:763-772
The regulation of the synthesis of the endothelial-derived vasoconstrictor ET-1 (endothelin-1) is a complex process that occurs mainly at the mRNA level. Transcription of the gene accounts for an important part of the regulation of expression, as alr
Autor:
Fernando Rodríguez-Pascual, Santiago Lamas, Mariano Redondo-Horcajo, Francisco Manuel Reimunde
Publikováno v:
Journal of cardiovascular pharmacology. 44
Expression of the endothelin-1 gene is subject to complex regulation by different factors, among which transforming growth factor-beta is one of the most important. We have analyzed the mechanism by which transforming growth factor-beta increases end