Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Francisco M. Rausa"'
Autor:
Yunzhao Xing, Sheng Zhong, Samuel L. Aronson, Francisco M. Rausa, Dan E. Webster, Michelle H. Crouthamel, Li Wang
Publikováno v:
Digital Biomarkers, Vol 8, Iss 1, Pp 13-21 (2024)
Introduction: Image-based machine learning holds great promise for facilitating clinical care; however, the datasets often used for model training differ from the interventional clinical trial-based findings frequently used to inform treatment guidel
Externí odkaz:
https://doaj.org/article/68f064e5d8d845a19f56219bd65f5a73
Autor:
Yuichi Yoshida, Douglas E. Hughes, Robert H. Costa, Gretchen J. Darlington, Yongjun Tan, Il-man Kim, Francisco M. Rausa
Publikováno v:
Hepatology. 43:276-286
We previously demonstrated that formation of complexes between the DNA-binding domains of hepatocyte nuclear factor 6 (HNF6) and forkhead box a2 (Foxa2) proteins stimulated Foxa2 transcriptional activity. Here, we used HepG2 cell cotransfection assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::238290a1ca14de555ea1d85ff0c05025
https://doi.org/10.1002/hep.21044
https://doi.org/10.1002/hep.21044
Publikováno v:
Journal of Biological Chemistry. 279:43070-43076
We previously demonstrated that the formation of complexes between the DNA binding domains of the hepatocyte nuclear factor 6 (HNF6) and Forkhead Box a2 (Foxa2) transcription factors resulted in synergistic transcriptional activation of a Foxa2 targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b232f8f693917ed8d5dd1928db0af88b
https://doi.org/10.1074/jbc.m407472200
https://doi.org/10.1074/jbc.m407472200
Autor:
Robert H. Costa, Yongjun Tan, Simon C. Watkins, Donna B. Stolz, Roberta Franks, Heping Zhou, Terry G. Unterman, Francisco M. Rausa, Kyung W. Yoo
Publikováno v:
Molecular and Cellular Biology. 20:8264-8282
The winged helix transcription factor, hepatocyte nuclear factor-3beta (HNF-3beta), mediates the hepatocyte-specific transcription of numerous genes important for liver function. However, the in vivo role of HNF-3beta in regulating these genes remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d03a7dafd7f34a95e1515ca355a0c6
https://doi.org/10.1128/.20.21.8264-8282.2000
https://doi.org/10.1128/.20.21.8264-8282.2000
Publikováno v:
Journal of Biological Chemistry. 272:672-679
The alpha2,6-sialyltransferase (ST) is a Golgi glycosyltransferase that adds sialic acid residues to glycoprotein N-linked oligosaccharides. Here we show that two forms of alpha2,6-sialyltransferase are expressed by the liver and are encoded by two d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9d95708f62683441b3e56f06ef401ee
https://doi.org/10.1074/jbc.272.1.672
https://doi.org/10.1074/jbc.272.1.672
Autor:
David L. Amrani, Sharon Pokropinski, Richard J. Johnson, Stephen L. Smith, Francisco M. Rausa, Lory Campro
Publikováno v:
The FASEB Journal. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eeb2c65e57ab8a06f6c68b14d9d03ece
https://doi.org/10.1096/fasebj.22.1_supplement.666.14
https://doi.org/10.1096/fasebj.22.1_supplement.666.14
Autor:
Debbie Rice, Brian McCallister, Sharon Pokropinski, Delara Motlagh, David L. Amrani, Jerome H. Gass, Lora Palmer, Laura Anderson, Jeff McKee, John Kemshead, Francisco M. Rausa, Bhumi Jasani
Publikováno v:
The FASEB Journal. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51be91e5c4d1791ab3b198b61000c961
https://doi.org/10.1096/fasebj.22.1_supplement.1123.23
https://doi.org/10.1096/fasebj.22.1_supplement.1123.23
Publikováno v:
The Journal of biological chemistry. 279(32)
Hepatocyte nuclear factor 6 (HNF-6) belongs to the family of One Cut transcription factors (also known as OC-1) and is essential for the development of the mouse pancreas, gall bladder, and the interhepatic bile ducts. HNF-6 binds to DNA as a monomer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d25242b9270d95d454b32722de0e51a
https://pubmed.ncbi.nlm.nih.gov/15169783
https://pubmed.ncbi.nlm.nih.gov/15169783
Autor:
Simon C. Watkins, Brian Shin, Vladimir V. Kalinichenko, Jeffrey A. Whitsett, Jean C. Clark, Robert H. Costa, Donna B. Stolz, Lorena Lim, Francisco M. Rausa
Publikováno v:
Developmental biology. 235(2)
Decreased pulmonary expression of Forkhead Box f1 (Foxf1) transcription factor was associated with lethal alveolar hemorrhage in 55% of the Foxf1 +/− newborn mice. The severity of the pulmonary abnormalities correlates with the levels of Foxf1 mRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef7c0f403b5c2ea5865ac4d211f781ed
https://pubmed.ncbi.nlm.nih.gov/11437453
https://pubmed.ncbi.nlm.nih.gov/11437453
Publikováno v:
Mechanisms of development. 89(1-2)
During organogenesis, the winged helix hepatocyte nuclear factor 3 β (HNF-3 β ) protein participates in regulating gene transcription in the developing esophagus, trachea, liver, lung, pancreas, and intestine. Hepatoma cell transfection studies ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb4464ca8175f90af171ee49707a5169
https://pubmed.ncbi.nlm.nih.gov/10559496
https://pubmed.ncbi.nlm.nih.gov/10559496