Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Francisco M. Franco"'
Autor:
James W. Janetka, Darin E. Jones, Zhenfu Han, Peter K. Harris, Francisco M. Franco, Cassie M. Jarvis, Scott A. Wildman
Publikováno v:
Bioorganic & Medicinal Chemistry. 23:2328-2343
Hepatocyte growth factor activator (HGFA), matriptase and hepsin are all S1 trypsin-like serine endopeptidases. HGFA is a plasma protease while hepsin and matriptase are type II transmembrane proteases (TTSPs). Upregulated expression and activity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07abb2fd8120897238c7918e9ec33eb7
https://doi.org/10.1016/j.bmc.2015.03.072
https://doi.org/10.1016/j.bmc.2015.03.072
Autor:
Daniel P. Walker, Alexander F. Shaffer, William M. Moore, Michael T. Baratta, Sue Metz, Jeffrey A. Scholten, John Robert Springer, Jeffrey S. Carter, Hwang-Fun Lu, Steven E. Heasley, Yvette M. Fobian, Natasha M. Kablaoui, Francisco M. Franco, Li Xing, Shengtian Yang, Hanau Cathleen E, Michael L. Vazquez, Graciela B. Arhancet, Gina M. Jerome
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 23:1120-1126
Microsomal prostaglandin E(2) synthase-1 (mPGES-1) is a novel therapeutic target for the treatment of inflammation and pain. In the preceding letter, we detailed the discovery of clinical candidate PF-04693627, a potent mPGES-1 inhibitor possessing a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2d05bf0698be13f2291735a95c4465f
https://doi.org/10.1016/j.bmcl.2012.11.107
https://doi.org/10.1016/j.bmcl.2012.11.107