Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Francisco M Bastos de Oliveira"'
Autor:
Xiaomu Wei, Jishnu Das, Robert Fragoza, Jin Liang, Francisco M Bastos de Oliveira, Hao Ran Lee, Xiujuan Wang, Matthew Mort, Peter D Stenson, David N Cooper, Steven M Lipkin, Marcus B Smolka, Haiyuan Yu
Publikováno v:
PLoS Genetics, Vol 10, Iss 12, p e1004819 (2014)
Understanding the functional relevance of DNA variants is essential for all exome and genome sequencing projects. However, current mutagenesis cloning protocols require Sanger sequencing, and thus are prohibitively costly and labor-intensive. We desc
Externí odkaz:
https://doaj.org/article/520bfb2ab08946fca05281b99ffe8bde
Autor:
Fabricio S Belgrano, Isabel C de Abreu da Silva, Francisco M Bastos de Oliveira, Marcelo R Fantappié, Ronaldo Mohana-Borges
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79572 (2013)
High mobility group box (HMGB) proteins are abundant nonhistone proteins found in all eukaryotic nuclei and are capable of binding/bending DNA. The human HMGB1 is composed of two binding motifs, known as Boxes A and B, are L-shaped alpha-helix struct
Externí odkaz:
https://doaj.org/article/98f9b80dc3b047769972daa107f50c0b
Publikováno v:
Nature
In response to genotoxic stress, a transient arrest in cell-cycle progression enforced by the DNA-damage checkpoint (DDC) signalling pathway positively contributes to genome maintenance. Because hyperactivated DDC signalling can lead to a persistent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::338f85ee024a3c8416a79d1b48c76c11
https://doi.org/10.1038/nature11658
https://doi.org/10.1038/nature11658
Autor:
Michael R. Harris, Marcus B. Smolka, Francisco M. Bastos de Oliveira, Robertus A.M. de Bruin, Pijus Brazauskas
Publikováno v:
The EMBO Journal. 31:1798-1810
Reprogramming gene expression is crucial for DNA replication stress response. We used quantitative proteomics to establish how the transcriptional response results in changes in protein levels. We found that expression of G1/S cell-cycle targets are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d210976db563ac1c9789ddff536c901d
https://doi.org/10.1038/emboj.2012.27
https://doi.org/10.1038/emboj.2012.27
Publikováno v:
Molecular Cell. 39:300-306
The DNA damage checkpoint kinase Mec1(ATR) is critical for maintaining the integrity of replication forks. Though it has been proposed to promote fork repair, the mechanisms by which Mec1 regulates DNA repair factors remain unclear. Here, we found th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a482bb524e57ed796f1ab3dcf44e46
https://doi.org/10.1016/j.molcel.2010.06.019
https://doi.org/10.1016/j.molcel.2010.06.019
Autor:
Haiyuan Yu, José Renato Rosa Cussiol, Jishnu Das, Kristina H. Schmidt, Francisco M. Bastos de Oliveira, Dongsung Kim, Min Cheol Jeong, Marcus B. Smolka, Lillian Doerfler
Publikováno v:
Molecular Cell. 58(1)
Summary The Mec1/Tel1 kinases (human ATR/ATM) play numerous roles in the DNA replication stress response. Despite the multi-functionality of these kinases, studies of their in vivo action have mostly relied on a few well-established substrates. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1ec3274f6a4dcefeadf4d09caa45450
Autor:
Francisco M, Bastos de Oliveira, Michael R, Harris, Pijus, Brazauskas, Robertus A M, de Bruin, Marcus B, Smolka
Publikováno v:
The EMBO journal. 31(7)
Reprogramming gene expression is crucial for DNA replication stress response. We used quantitative proteomics to establish how the transcriptional response results in changes in protein levels. We found that expression of G1/S cell-cycle targets are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f51727dfe0b6b2bc9dc2d65110459628
https://pubmed.ncbi.nlm.nih.gov/22333912
https://pubmed.ncbi.nlm.nih.gov/22333912
Autor:
Jishnu Das, David Neil Cooper, Matthew Mort, Xiujuan Wang, Jin Liang, Haiyuan Yu, Hao Ran Lee, Steven M. Lipkin, Marcus B. Smolka, Robert Fragoza, Xiaomu Wei, Peter D. Stenson, Francisco M. Bastos de Oliveira
Publikováno v:
PLoS Genetics, Vol 10, Iss 12, p e1004819 (2014)
PLoS Genetics
PLoS Genetics
Understanding the functional relevance of DNA variants is essential for all exome and genome sequencing projects. However, current mutagenesis cloning protocols require Sanger sequencing, and thus are prohibitively costly and labor-intensive. We desc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2e59b3fc30897d4771fbfda3b36f9ab
https://doi.org/10.1371/journal.pgen.1004819
https://doi.org/10.1371/journal.pgen.1004819
Autor:
Isabel Caetano de Abreu da Silva, Fabricio dos Santos Belgrano, Marcelo Rosado Fantappié, Francisco M. Bastos de Oliveira, Ronaldo Mohana-Borges
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 11, p e79572 (2013)
PLoS ONE, Vol 8, Iss 11, p e79572 (2013)
High mobility group box (HMGB) proteins are abundant nonhistone proteins found in all eukaryotic nuclei and are capable of binding/bending DNA. The human HMGB1 is composed of two binding motifs, known as Boxes A and B, are L-shaped alpha-helix struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deb167e25da3db2bc85149162f0703aa
https://doi.org/10.1371/journal.pone.0079572
https://doi.org/10.1371/journal.pone.0079572
Autor:
José Renato Rosa Cussiol, Askar Yimit, Katsuhiko Shirahige, Marcus B. Smolka, Attila Balint, Ryuichiro Nakato, TaeHyung Kim, David Gallo, Francisco M. Bastos de Oliveira, Zhaolei Zhang, Jiongwen Ou, Grant W. Brown, Alexey Gurevich
Publikováno v:
ResearcherID
Obstructions to replication fork progression, referred to collectively as DNA replication stress, challenge genome stability. In Saccharomyces cerevisiae, cells lacking RTT107 or SLX4 show genome instability and sensitivity to DNA replication stress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce94160ab99ba0a2728a1311eccd5854
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000359480900007&KeyUID=WOS:000359480900007
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000359480900007&KeyUID=WOS:000359480900007
