Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Francisco Ledo"'
Autor:
Marina Mojena, Adrián Povo-Retana, Silvia González-Ramos, Victoria Fernández-García, Javier Regadera, Arturo Zazpe, Inés Artaiz, Paloma Martín-Sanz, Francisco Ledo, Lisardo Boscá
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Melanomas are heterogeneous and aggressive tumors, and one of the worse in prognosis. Melanoma subtypes follow distinct pathways until terminal oncogenic transformation. Here, we have evaluated a series of molecules that exhibit potent cytotoxic effe
Externí odkaz:
https://doaj.org/article/00f532f70f4249eaa1322bb45a89dce0
Publikováno v:
Drug and chemical toxicology. 38(4)
Bilastine is a new oral selective, non-sedating histamine H1 antagonist for the symptomatic treatment of allergic rhinoconjunctivitis and urticaria. The European Medicines Agency requires an Environmental Risk Assessment (ERA) for all novel medicines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fffeee66b0e11a02dfe530bf291bfa3
https://pubmed.ncbi.nlm.nih.gov/25609003
https://pubmed.ncbi.nlm.nih.gov/25609003
Autor:
Marcos Garcia-Fuentes, Maria Alonso-Sande, María Luisa Lucero, Francisco Ledo, María J. Alonso, Pablo Hervella
Publikováno v:
Scopus-Elsevier
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
Drugs with poor lipid and water solubility are some of the most challenging to formulate in nanocarriers, typically resulting in low encapsulation efficiencies and uncontrolled release profiles. PEGylated nano- capsules (PEG-NC) are known for their a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed5bd6572c2ee6948e42f85348a87716
https://hdl.handle.net/10347/11294
https://hdl.handle.net/10347/11294
Autor:
Maria Teresa Nunez, Francisco Ledo, Erden Banoglu, Bilge Çakir, Gretchen Bain, Burcu Caliskan Erguen, Janice Darlington, Luis Labeaga
Publikováno v:
ChemInform. 41
A variety of 1,5-diarylpyrazol-3-propanoic acid derivatives is synthesized and evaluated as COX-1/2 and 5-LO-mediated LTB4 synthesis inhibitors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2a33b7ca7557141d6780656ef798f99
https://doi.org/10.1002/chin.201051152
https://doi.org/10.1002/chin.201051152
Autor:
Luis Labeaga, Francisco Ledo, Gretchen Bain, Burcu Çaliskan Ergün, Maria Teresa Nuñe, Bilge Çakir, Janice Darlington, Erden Banoglu
A set of 25 derivatives of 3-[1-(6-substituted-pyridazin-3-yl)-5-(4- substitutedphenyl)-1H-pyrazol-3-yl]propanoic acids has been synthesized and evaluated for their in vitro cyclooxygenase-1/2 (COX-1/ 2) inhibitory activity using assays with purified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8138d1770cdb17603d1cb27ec2ebba57
https://avesis.gazi.edu.tr/publication/details/85be7515-04f8-4a78-b7fc-b79341c63d8b/oai
https://avesis.gazi.edu.tr/publication/details/85be7515-04f8-4a78-b7fc-b79341c63d8b/oai
Autor:
Maria-Teresa Nunez, Francisco Ledo, Ningur Noyanalpan, M. Fethi Şahin, Erden Banoglu, Gabriele Costantino, Antonio Entrena, Serdar Uenlue, Yasemin Duendar
Publikováno v:
ChemInform. 40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2438f293d6dcf31832894ea2355dd342
https://doi.org/10.1002/chin.200934123
https://doi.org/10.1002/chin.200934123
Autor:
Yasemin, Dündar, Serdar, Unlü, Erden, Banoğlu, Antonio, Entrena, Gabriele, Costantino, Maria-Teresa, Nuñez, Maria-Teresa, Nunez, Luis, Labeaga, Francisco, Ledo, M Fethi, Sahin, Ningur, Noyanalpan
A series of 3-unsubstituted/substituted-4,5-diphenyl-2-oxo-3H-1,3-oxazole derivatives were prepared as selective cyclooxygenase-2 (COX-2) inhibitors. Among the synthesized compounds, 4-(4-phenyl-3-methyl-2-oxo-3H-1,3-oxazol-5-yl)benzensulfonamide (co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c752a2b47e20b598cedad1bd3d6974
https://avesis.gazi.edu.tr/publication/details/043d3ff2-9f14-4d64-b55e-cea911b18bf6/oai
https://avesis.gazi.edu.tr/publication/details/043d3ff2-9f14-4d64-b55e-cea911b18bf6/oai
Autor:
Ana Muñoz, Juan Antonio Gallardo, Francisco Ledo, José Ramón Murguía, Rosendo Hernández, Alicia Boto, Carlos Javier Saavedra, Aurelio Orjales, Mauricio Menacho-Márquez
Publikováno v:
Bioorganicmedicinal chemistry letters. 16(23)
The discovery of genotoxic amino acids derived from phenylglycine, and possessing halogen substituents, is described. The utility of hypervalent iodine reagents in the synthesis of this class of compounds is highlighted. The mechanism of action of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::097068da193601c633fa7bafaa3e71d9
https://pubmed.ncbi.nlm.nih.gov/16990000
https://pubmed.ncbi.nlm.nih.gov/16990000
Autor:
Ningur Noyanalpan, Francisco Ledo, M. Fethi Şahin, Serdar Ünlü, Erden Banoglu, Yasemin Dündar, Gabriele Costantino, Maria-Teresa Nunez, Antonio Entrena
Publikováno v:
European Journal of Medicinal Chemistry. 44:4785
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68829e57dbd720fd4c67248a5d9a8813
https://doi.org/10.1016/j.ejmech.2009.05.020
https://doi.org/10.1016/j.ejmech.2009.05.020