Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Francisco José Nicolas"'
Autor:
Begoña Alburquerque-González, Manuel Bernabé-García, Silvia Montoro-García, Ángel Bernabé-García, Priscila Campioni Rodrigues, Javier Ruiz Sanz, Fernando F. López-Calderón, Irene Luque, Francisco José Nicolas, María Luisa Cayuela, Tuula Salo, Horacio Pérez-Sánchez, Pablo Conesa-Zamora
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 2, Pp 281-292 (2020)
Colorectal cancer: Antitumor antidepressant The antidepressant drug imipramine can block the activity of a protein that contributes to the progression of certain aggressive tumors. Serrated adenocarcinoma (SAC) is a form of colorectal cancer with a p
Externí odkaz:
https://doaj.org/article/a4c0dcae753643f4b932658c0f7d73c0
Autor:
Mónica Rodríguez-Valiente, Ana M. García-Hernández, Cristina Fuente-Mora, Javier Sánchez-Gálvez, Eva María García-Vizcaino, Elena Tristante Barrenechea, Gregorio Castellanos Escrig, Sergio David Liarte Lastra, Francisco Jose Nicolás
Publikováno v:
Biomedicines, Vol 12, Iss 10, p 2380 (2024)
Chronic wounds are defined as those with disturbances in normal healing. They involve symptoms like exudate, odor, pain or impaired mobility, severely impacting life quality. In the case of patients with additional comorbidities, these are known to a
Externí odkaz:
https://doaj.org/article/322b5b375e44478db4f6c920e762fcb7
Autor:
Javier Stelling-Férez, Ilaria Cappellacci, Assunta Pandolfi, José Antonio Gabaldón, Caterina Pipino, Francisco José Nicolás
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Skin wound healing is a physiological process that involves several cell types. Among them, endothelial cells are required for inflammation resolution and neo‐angiogenesis, both necessary for tissue restoration after injury. Primary human umbilical
Externí odkaz:
https://doaj.org/article/3e0ef33fa18e487c93d449c8ee4234c2
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Cell migration is a critical process for wound healing, a physiological phenomenon needed for proper skin restoration after injury. Wound healing can be compromised under pathological conditions. Natural bioactive terpenoids have shown promi
Externí odkaz:
https://doaj.org/article/89fe1ad6043c40e7b8f6b7532ecbb62c
Autor:
Caterina Pipino, Ángel Bernabé-García, Ilaria Cappellacci, Javier Stelling-Férez, Pamela Di Tomo, Manuela Santalucia, Carlos Navalón, Assunta Pandolfi, Francisco José Nicolás
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
One of the most relevant diabetes complications is impaired wound healing, mainly characterized by reduced peripheral blood flow and diminished neovascularization together with increased inflammation and oxidative stress. Unfortunately, effective the
Externí odkaz:
https://doaj.org/article/d0347d22e98e48e587c75f35ff89fc75
Autor:
Catalina Ruiz-Cañada, Ángel Bernabé-García, Sergio Liarte, Mónica Rodríguez-Valiente, Francisco José Nicolás
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
The application of amniotic membrane (AM) on chronic wounds has proven very effective at resetting wound healing, particularly in re-epithelialization. Historically, several aspects of AM effect on wound healing have been evaluated using cell models.
Externí odkaz:
https://doaj.org/article/885c461385554076b48fd0ffff252d08
Publikováno v:
Cell Communication and Signaling, Vol 15, Iss 1, Pp 1-17 (2017)
Abstract Background The simplicity of Transforming Growth Factor ß (TGFβ) signaling pathway, linear and non-amplified, hardly sustains its variety of responses. This is often justified by the complex regulation showed by Smad proteins, TGFβ signal
Externí odkaz:
https://doaj.org/article/3e43f93adeb2462da7a50afcebadc69c
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Breast cancer remains a significant female mortality cause. It constitutes a multifactorial disease for which research on environmental factors offers little help in predicting onset or progression. The pursuit for its foundations by analyzing hormon
Externí odkaz:
https://doaj.org/article/578cd3bc135f4260807a6e192763c11a
Autor:
Ángel Bernabé-García, David Armero-Barranco, Sergio Liarte, María Ruzafa-Martínez, Antonio Jesús Ramos-Morcillo, Francisco José Nicolás
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172574 (2017)
During wound healing, skin function is restored by the action of several cell types that undergo differentiation, migration, proliferation and/or apoptosis. These dynamics are tightly regulated by the evolution of the extra cellular matrix (ECM) cont
Externí odkaz:
https://doaj.org/article/c78d4e41460248e4952a7056f87b3800
Autor:
Antonia Alcaraz, Anna Mrowiec, Carmen Luisa Insausti, Ángel Bernabé-García, Eva María García-Vizcaíno, María Concepción López-Martínez, Asunción Monfort, Ander Izeta, José María Moraleda, Gregorio Castellanos, Francisco José Nicolás
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135324 (2015)
BACKGROUND:Post-traumatic large-surface or deep wounds often cannot progress to reepithelialisation because they become irresponsive in the inflammatory stage, so intervention is necessary to provide the final sealing epidermis. Previously we have sh
Externí odkaz:
https://doaj.org/article/440a9cf9e32747e6bc0c435972075b96