Characteristics of hepatitis C virus resistance in an international cohort after a decade of direct-acting antivirals

Autor: Anita Y.M. Howe, Chaturaka Rodrigo, Evan B. Cunningham, Mark W. Douglas, Julia Dietz, Jason Grebely, Stephanie Popping, Javier Alejandro Sfalcin, Milosz Parczewski, Christoph Sarrazin, Adolfo de Salazar, Ana Fuentes, Murat Sayan, Josep Quer, Midori Kjellin, Hege Kileng, Orna Mor, Johan Lennerstrand, Slim Fourati, Velia Chiara Di Maio, Vladimir Chulanov, Jean-Michel Pawlotsky, P. Richard Harrigan, Francesca Ceccherini-Silberstein, Federico Garcia, Marianne Martinello, Gail Matthews, Fay Fabián Fernando, Juan I. Esteban, Beat Müllhaupt, Julian Schulze zur Wiesch, Peter Buggisch, Christoph Neumann-Haefelin, Thomas Berg, Christoph P. Berg, Jörn M. Schattenberg, Christophe Moreno, Rudolf Stauber, Andrew Lloyd, Gregory Dore, Tanya Applegate, Juan Ignacio, Damir Garcia-Cehic, Josep Gregori, Francisco Rodriguez-Frias, Ariadna Rando, Yael Gozlan, Mario Angelico, Massimo Andreoni, Sergio Babudieri, Ada Bertoli, Valeria Cento, Nicola Coppola, Antonio Craxì, Stefania Paolucci, Giustino Parruti, Caterina Pasquazzi, Carlo Federico Perno, Elisabetta Teti, C. Vironet, Anders Lannergård, Ann-Sofi Duberg, Soo Aleman, Tore Gutteberg, Alexandre Soulier, Aurélie Gourgeon, Stephane Chevaliez, Stanislas Pol, Fabrice Carrat, Dominique Salmon, Rolf Kaiser, Elena Knopes, Perpetua Gomes, Rob de Kneght, Bart Rijnders, Mario Poljak, Maja Lunar, Rafael Usubillaga, Carole Seguin_Devaux, Enoch Tay, Caroline Wilson, Dao Sen Wang, Jacob George, Jen Kok, Ana Belén Pérez, Natalia Chueca, Miguel García-Deltoro, Ana María Martínez-Sapiña, María Magdalena Lara-Pérez, Silvia García-Bujalance, Teresa Aldámiz-Echevarría, Francisco Jesús Vera-Méndez, Juan Antonio Pineda, Marta Casado, Juan Manuel Pascasio, Javier Salmerón, Juan Carlos Alados-Arboledas, Antonio Poyato, Francisco Téllez, Antonio Rivero-Juárez, Dolores Merino, María Jesús Vivancos-Gallego, José Miguel Rosales-Zábal, María Dolores Ocete, Miguel Ángel Simón, Pilar Rincón, Sergi Reus, Alberto De la Iglesia, Isabel García-Arata, Miguel Jiménez, Fernando Jiménez, José Hernández-Quero, Carlos Galera, Mohamed Omar Balghata, Joaquín Primo, Mar Masiá, Nuria Espinosa, Marcial Delgado, Miguel Ángel von-Wichmann, Antonio Collado, Jesús Santos, Carlos Mínguez, Felícitas Díaz-Flores, Elisa Fernández, Enrique Bernal, José De Juan, José Joaquín Antón, Mónica Vélez, Antonio Aguilera, Daniel Navarro, Juan Ignacio Arenas, Clotilde Fernández, María Dolores Espinosa, María José Ríos, Roberto Alonso, Carmen Hidalgo, Rosario Hernández, María Jesús Téllez, Francisco Javier Rodríguez, Pedro Antequera, Cristina Delgado, Patricia Martín, Javier Crespo, Berta Becerril, Oscar Pérez, Antonio García-Herola, José Montero, Carolina Freyre, Concepción Grau, Joaquin Cabezas, Miguel Jimenez, Manuel Alberto Macias Rodriguez, Cristina Quilez, Maria Rodriguez Pardo, Leopoldo Muñoz-Medina, Blanca Figueruela

Publikováno v: JHEP Reports, Vol 4, Iss 5, Pp 100462- (2022)

Background & Aims: Direct-acting antiviral (DAA) regimens provide a cure in >95% of patients with chronic HCV infection. However, in some patients in whom therapy fails, resistance-associated substitutions (RASs) can develop, limiting retreatment opt

Externí odkaz: https://doaj.org/article/f2e6a1ce74794d3c98e6f58a4144688c

Liver stiffness change with HCV cure in HIV-infected patients on non-nucleoside analogues

Autor: Dolores Merino, Anaïs Corma-Gómez, Juan A. Pineda, Francisco Jesús Vera-Méndez, I De Los Santos, Antonio Rivero-Juárez, Juan Macías, Mario Frias, Carlos Galera, Luis Morano, Miriam Serrano, Alejandro González-Serna, Francisco Téllez, Arkaitz Imaz, S García-Martin

Publikováno v: Journal of Antimicrobial Chemotherapy. 76:2375-2379

Background Liver stiffness (LS) at sustained viral response (SVR) is strongly associated with a lower incidence of subsequent hepatic events. HIV NNRTIs may have a beneficial impact on fibrogenesis. Objectives Our aim was to analyse the influence of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd793e6f907a9a12d07a6bd781fecb7
https://doi.org/10.1093/jac/dkab157

High efficacy of resistance-guided retreatment of HCV patients failing NS5A inhibitors in the real world

Autor: Ana María Martínez-Sapiña, Concepción Grau, Maria Rios, Javier Crespo, Óscar Pérez, Elisa Fernández, Antonio Rivero-Juárez, Carlos Mínguez, Juan Carlos Alados-Arboledas, Miguel Jimenez, Joaquín Primo, Antonio Poyato, Juan Manuel Pascasio, Mónica Vélez, Natalia Chueca, Juan Arenas, Javier Salmerón, Berta Becerril, José Luis Montero, María Dolores Ocete, Clotilde Fernández, Marta Casado, Sergi Reus, Teresa Aldámiz-Echevarría, Carolina Freyre, Pedro Antequera, María Jesús Vivancos-Gallego, Carmen Hidalgo, Miguel Angel Simón, Cristina Delgado, Alberto de la Iglesia, Dolores Merino, Enrique Bernal, Mar Masiá, José Hernández-Quero, Daniel Navarro, Nuria Espinosa, Carlos Galera, Federico García, Ana Belén Pérez, Antonio Aguilera, Jesús Santos, Patricia Martín, Fernando Jiménez, María Jesús Téllez, José Miguel Rosales-Zábal, Silvia García-Bujalance, Juan A. Pineda, María Magdalena Lara-Pérez, Francisco Téllez, Marcial Delgado, Pilar Rincón, Francisco Javier Rodríguez, Roberto Alonso, José De Juan, Antonio García-Herola, María Dolores Espinosa, Antonio Collado, Francisco Jesús Vera-Méndez, Rosario Hernández, José Joaquin Antón, Miguel Ángel Von-Wichmann, Miguel García-Deltoro, Isabel García-Arata, Felicitas Diaz-Flores, Mohamed Omar Balghata

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
JOURNAL OF HEPATOLOGY
r-FISABIO. Repositorio Institucional de Producción Científica
r-FIHGUV. Repositorio Institucional de Producción Científica de la Fundación de Investigación del Hospital General de Valencia
r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante

GEHEP-004 Study Group: María Dolores Ocete, Miguel Ángel Simón, Pilar Rincón, Sergi Reus, Alberto De la Iglesia, Isabel García-Arata, Miguel Jiménez, Fernando Jiménez, José Hernández-Quero, Carlos Galera, Mohamed Omar Balghata, Joaquín Prim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::466394b42e52307b8018180f71497660
https://doi.org/10.1016/j.jhep.2019.06.022

Human Immunodeficiency Virus (HIV) Infection Is Associated With Lower Risk of Hepatocellular Carcinoma After Sustained Virological Response to Direct-acting Antivirals in Hepatitis C Infected Patients With Advanced Fibrosis

Autor: Anaïs, Corma-Gómez, Juan, Macías, Juan Ramón, Lacalle-Remigio, Francisco, Téllez, Luis, Morano, Antonio, Rivero, Miriam, Serrano, María José, Ríos, Francisco Jesús, Vera-Méndez, Juan Carlos, Alados, Luis Miguel, Real, Rosario, Palacios, Ignacio De Los, Santos, Arkaitz, Imatz, Juan Antonio, Pineda, Inés, Pérez Camacho

Publikováno v: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 73(7)

Background The aim of this study was to assess the impact of human immunodeficiency virus (HIV) infection on the risk of developing hepatocellular carcinoma (HCC) in patients infected with hepatitis C virus (HCV) who achieve sustained virological res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdfc68ede2b83bc12fdac094721e3d68
https://pubmed.ncbi.nlm.nih.gov/32766891

Liver Stiffness at the Time of Sustained Virological Response Predicts the Clinical Outcome in People Living With Human Immunodeficiency Virus and Hepatitis C Virus With Advanced Fibrosis Treated With Direct-acting Antivirals

Autor: Juan Macías, M.J. Ríos, Luis Morano, Juan Carlos Alados, Nicolás Merchante, Francisco Téllez, I De Los Santos, Dolores Merino, Antonio Rivero-Juárez, Rosario Palacios, Rafael Granados, Anaïs Corma-Gómez, Francisco Jesús Vera-Méndez, Juan A. Pineda, Carolina Freyre-Carrillo

Publikováno v: Clinical Infectious Diseases.

Background Some people living with hepatitis C virus (HCV) with sustained virological response (SVR) develop hepatic complications. Liver stiffness (LS) predicts clinical outcome in people living with human immunodeficiency virus (HIV) with active HC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3971355700e913ea92a3452f3c0a9424
https://doi.org/10.1093/cid/ciz1140