Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Francisco Javier Gil-Bea"'
Autor:
Jon Ondaro, Haizea Hernandez-Eguiazu, Maddi Garciandia-Arcelus, Raúl Loera-Valencia, Laura Rodriguez-Gómez, Andrés Jiménez-Zúñiga, Julen Goikolea, Patricia Rodriguez-Rodriguez, Javier Ruiz-Martinez, Fermín Moreno, Adolfo Lopez de Munain, Ian James Holt, Francisco Javier Gil-Bea, Gorka Gereñu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Neurons are post-mitotic cells that allocate huge amounts of energy to the synthesis of new organelles and molecules, neurotransmission and to the maintenance of redox homeostasis. In neurons, autophagy is not only crucial to ensure organelle renewal
Externí odkaz:
https://doaj.org/article/d5a931fe69ce457aa2252150533d313b
Autor:
Javier Riancho, Francisco Javier Gil-Bea, María Dolores Andreu, Adolfo López de Munain, Sara Arozamena, Lucía Paz-Fajardo, Manuel Delgado-Alvarado
Publikováno v:
British Journal of Pharmacology. 178:1269-1278
Amyotrophic lateral sclerosis (ALS) commonly referred to as motor neurone disease, is a neurodegenerative disease of unknown pathogenesis that progresses rapidly and has attracted an increased amount of scholarly interest in recent years. The current
Autor:
Javier Riancho, Miguel Lafarga, Carlos Durán-Vían, Olga Tapia, Francisco Javier Gil-Bea, Jana Arozamena, David Castanedo-Vazquez, Adolfo López de Munain, María José Sedano, Maria T. Berciano
Publikováno v:
Journal of Neurology. 267:1291-1299
Dermic fibroblasts have been proposed as a potential genetic-ALS cellular model. This study aimed to explore whether dermic fibroblasts from patients with sporadic-ALS (sALS) recapitulate alterations typical of ALS motor neurons and exhibit abnormal
Autor:
Adolfo López de Munain, Sonia Alonso-Martín, Francisco Javier Gil-Bea, Gorka Gerenu, Neia Naldaiz-Gastesi, Oihane Pikatza-Menoio, Xabier Bengoetxea, Amaia Elicegui
Publikováno v:
Journal of Personalized Medicine, Vol 11, Iss 671, p 671 (2021)
Journal of Personalized Medicine
Journal of Personalized Medicine
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder that leads to progressive degeneration of motor neurons (MNs) and severe muscle atrophy without effective treatment. Most research on ALS has been focused on the study of MNs a
Autor:
A. Lleo, Oskar Hansson, Gorka Fernández-Eulate, Bruce L. Miller, Pedro Rosa-Neto, Nicholas J. Ashton, Ahmad Al Khleifat, Susan M. Resnick, Erik Stomrud, Lucilla Parnetti, Latha Velayudhan, Sebastian Palmqvist, Thomas K. Karikari, Kaj Blennow, Gil D. Rabinovici, Andrea Lessa Benedet, Francisco Javier Gil-Bea, Adolfo López de Munain, Lenka Novakova, Alessandro Padovani, Laura Bonanni, Carmine M. Pariante, Markus Axelsson, Naghmeh Nikkheslat, Alexander Santillo, Ammar Al-Chalabi, Abdul Hye, Henrik Zetterberg, Emma L. van der Ende, Andrea Pilotto, John C. van Swieten, Madhav Thambisetty, Dag Aarsland, Jan Lycke, Daniela Galimberti, Per Svenningsson, Michael Schöll, Shorena Janelidze, Tharick A. Pascoal, Andre Strydom, Antoine Leuzy
Publikováno v:
Nature Communications
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Nature communications, vol 12, iss 1
Nature Communications, 12(1):3400. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Nature communications, vol 12, iss 1
Nature Communications, 12(1):3400. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Increased cerebrospinal fluid neurofilament light (NfL) is a recognized biomarker for neurodegeneration that can also be assessed in blood. Here, we investigate plasma NfL as a marker of neurodegeneration in 13 neurodegenerative disorders, Down syndr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::321e1a9b9168bdbede33e42548b26c89
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=7766
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=7766
Autor:
Juan Bautista Espinal, Gorka Fernández-Eulate, Gorka Gerenu, Mónica Zufiría, Roberto Fernández-Torrón, Jon Ondaro, José Ignacio Ruiz-Sanz, Gonzalo GonzÁlez-ChinchÓn, Maria Begoña Ruiz-Larrea, Adolfo López de Munain, Miren Zulaica, Juan JosÉ Poza-Aldea, Francisco Javier Gil-Bea, Javier Riancho
Objective: To perform a comprehensive lipid profiling to evaluate potential lipid metabolic differences between patients with amyotrophic lateral sclerosis (ALS) and controls, and to provide a more profound understanding of the metabolic abnormalitie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18833443ce6347b6ab24e36acbfe8034
Autor:
Gorka Fernández Garcia de Eulate, Mónica Zufiría, Francisco Javier Gil-Bea, María José Sedano, Juan José Poza, Javier Riancho, David Castanedo-Vazquez, Adolfo López de Munain
Publikováno v:
Journal of the Neurological Sciences. 393:80-82
Publikováno v:
Neural Regen Res, 14 (2), 193-196 Feb 2019
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Neural Regeneration Research
Addi. Archivo Digital para la Docencia y la Investigación
instname
Neural Regeneration Research, Vol 14, Iss 2, Pp 193-196 (2019)
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Neural Regeneration Research
Addi. Archivo Digital para la Docencia y la Investigación
instname
Neural Regeneration Research, Vol 14, Iss 2, Pp 193-196 (2019)
Amyotrophic lateral sclerosis, the most common neurodegenerative disease affecting motor neurons, lacks an effective treatment. A small fraction of amyotrophic lateral sclerosis cases have a familial origin, related to mutations in causative genes, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c4053e953c765f2daa631207cea6345
http://hdl.handle.net/10810/32111
http://hdl.handle.net/10810/32111
Autor:
Gabriel Rodríguez-Romo, Jonatan R. Ruiz, Francisco-Javier Gil-Bea, Natalia Bustamante-Ara, José Antonio Serra-Rexach, Alejandro Lucia, Angel Cedazo-Minguez, Carmen Fiuza-Luces
Publikováno v:
International Journal of Sports Medicine. 36:54-60
The aim of this randomized controlled trial was to determine the effects of 8-week exercise-intervention on cognition and related serum biochemical markers in nonagenarians. We also studied the effects of a 4-week training cessation (‘detraining’
Autor:
Amilcar Flores-Morales, Stefan Spulber, Susanne Akterin, Francisco-Javier Gil-Bea, Laura Mateos, Marianne Schultzberg, Angel Cedazo-Minguez, Atiqur Rahman, Ingemar Björkhem
Publikováno v:
Brain Pathol
Growing evidence strongly suggests that high fat diet (HFD) has an important role in some neurodegenerative disorders, including Alzheimer's disease (AD). To identify new cellular pathways linking hypercholesterolemia and neurodegeneration, we analyz