Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Francisco J. Sierra-Valdez"'
Autor:
Luis O. Romero, Rebeca Caires, A. Kaitlyn Victor, Juanma Ramirez, Francisco J. Sierra-Valdez, Patrick Walsh, Vincent Truong, Jungsoo Lee, Ugo Mayor, Lawrence T. Reiter, Valeria Vásquez, Julio F. Cordero-Morales
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Angelman syndrome (AS) is a neurogenetic disorder. Here, the authors found that PIEZO2 activity is reduced in sensory neurons from a mouse model of AS and used a linoleic acid-enriched diet to enhance PIEZO2 function and ameliorate AS-associated gait
Externí odkaz:
https://doaj.org/article/664f09f3735d4266a19b95c85b38e994
Autor:
Luis O. Romero, Andrew E. Massey, Alejandro D. Mata-Daboin, Francisco J. Sierra-Valdez, Subhash C. Chauhan, Julio F. Cordero-Morales, Valeria Vásquez
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Piezo channels are mechanosensitive and rely on membrane composition to transduce physical stimuli into electrical signals. Here authors analyse the membrane components that modulate Piezo1 function using lipid profiling which shows that fatty acid m
Externí odkaz:
https://doaj.org/article/79b47773086f40d2b56953992c83ae64
Autor:
Rebeca Caires, Francisco J. Sierra-Valdez, Jonathan R.M. Millet, Joshua D. Herwig, Esra Roan, Valeria Vásquez, Julio F. Cordero-Morales
Publikováno v:
Cell Reports, Vol 21, Iss 1, Pp 246-258 (2017)
Dietary consumption of ω-3 polyunsaturated fatty acids (PUFAs), present in fish oils, is known to improve the vascular response, but their molecular targets remain largely unknown. Activation of the TRPV4 channel has been implicated in endothelium-d
Externí odkaz:
https://doaj.org/article/e656045fd9b34250bdf530e41fd89020
Publikováno v:
Biophysical Journal. 122:224a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcf52d58d4e656cae8d819699e2416c3
https://doi.org/10.1016/j.bpj.2022.11.1329
https://doi.org/10.1016/j.bpj.2022.11.1329
Autor:
Carol S, Velez-Saboyá, Eric, Oropeza-Guzman, Francisco J, Sierra-Valdez, Jesús C, Ruiz-Suárez
Publikováno v:
Biochimica et biophysica acta. Biomembranes. 1863(2)
Although sharing common properties with other divalent cations, calcium ions induce fine-tuned electrostatic effects essential in many biological processes. Not only related with protein structure or ion channels, calcium is also determinant for othe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b717df55c83915074da086e155102952
https://pubmed.ncbi.nlm.nih.gov/33189718
https://pubmed.ncbi.nlm.nih.gov/33189718
Publikováno v:
Journal of molecular graphicsmodelling. 101
n-Aliphatic alcohols act as anesthetics only up to a certain chain length, beyond which its biological activity disappears. This is known as the 'cut-off' phenomenon. Although the most accepted explanation is based on action sites in membrane protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f47a5e0a02b438535d17bd87d9fee602
https://pubmed.ncbi.nlm.nih.gov/32920240
https://pubmed.ncbi.nlm.nih.gov/32920240
Autor:
Francisco J. Sierra-Valdez, Luis O. Romero, Julio F. Cordero-Morales, Terunaga Nakagawa, Caleigh M. Azumaya
Publikováno v:
Journal of Biological Chemistry. 293:16102-16114
The transient receptor potential ion channels support Ca(2+) permeation in many organs, including the heart, brain, and kidney. Genetic mutations in transient receptor potential cation channel subfamily C member 3 (TRPC3) are associated with neurodeg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38f8d2df229ba51efc5fe505916906a4
https://doi.org/10.1074/jbc.ra118.005066
https://doi.org/10.1074/jbc.ra118.005066
Autor:
Francisco J. Sierra-Valdez, Valeria Vásquez, Herwig Joshua D, Julio F. Cordero-Morales, Jonathan R.M. Millet, Rebeca Caires, Esra Roan
Publikováno v:
Cell Rep
Cell Reports, Vol 21, Iss 1, Pp 246-258 (2017)
Cell Reports, Vol 21, Iss 1, Pp 246-258 (2017)
Dietary consumption of ω-3 polyunsaturated fatty acids (PUFAs), present in fish oils, is known to improve the vascular response, but their molecular targets remain largely unknown. Activation of the TRPV4 channel has been implicated in endothelium-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa1a4ea2d0a8c647f7ba90a542db899b
https://doi.org/10.1016/j.celrep.2017.09.029
https://doi.org/10.1016/j.celrep.2017.09.029
Autor:
Richard A. Stein, Valeria Vásquez, Phanindra Velisetty, Julio F. Cordero-Morales, Francisco J. Sierra Valdez
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports
Scientific Reports
The transient receptor potential vanilloid 1 (TRPV1) channel is an essential component of the cellular mechanism through which noxious stimuli evoke pain. Functional and structural characterizations of TRPV1 shed light on vanilloid activation, yet th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423578cbe58430bef2a900b14d7a504e
http://link.springer.com/article/10.1038/s41598-017-10426-7
http://link.springer.com/article/10.1038/s41598-017-10426-7
Autor:
Julio F. Cordero-Morales, Efren Garcia-Maldonado, Valeria Vásquez, Francisco J. Sierra Valdez
Publikováno v:
Biophysical Journal. 118:523a-524a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b78c26a9b32fc4e6cb34cc138dc4d9f2
https://doi.org/10.1016/j.bpj.2019.11.2878
https://doi.org/10.1016/j.bpj.2019.11.2878