Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Francisco J. M. Mojica"'
Autor:
Belen Esquerra‐Ruvira, Ignacio Baquedano, Raul Ruiz, Almudena Fernandez, Lluis Montoliu, Francisco J. M. Mojica
Publikováno v:
Microbial Biotechnology, Vol 16, Iss 7, Pp 1505-1523 (2023)
Abstract Non‐coding RNAs (crRNAs) produced from clustered regularly interspaced short palindromic repeats (CRISPR) loci and CRISPR‐associated (Cas) proteins of the prokaryotic CRISPR‐Cas systems form complexes that interfere with the spread of
Externí odkaz:
https://doaj.org/article/3709ef1a107745b49f0c8eaaf1f1b0db
Autor:
Oscar Salgado, Sergio Guajardo-Leiva, Ana Moya-Beltrán, Carla Barbosa, Christina Ridley, Javier Tamayo-Leiva, Raquel Quatrini, Francisco J. M. Mojica, Beatriz Díez
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The Cas1 protein is essential for the functioning of CRISPR-Cas adaptive systems. However, despite the high prevalence of CRISPR-Cas systems in thermophilic microorganisms, few studies have investigated the occurrence and diversity of Cas1 across hot
Externí odkaz:
https://doaj.org/article/03e064e581f442eea3b202a336e3497d
Publikováno v:
Microbial Cell, Vol 5, Iss 6, Pp 262-268219 (2018)
CRISPR-Cas represents a prokaryotic defense mechanism against invading genetic elements. Although there is a diversity of CRISPR-Cas systems, they all share similar, essential traits. In general, a CRISPR-Cas system consists of one or more groups of
Externí odkaz:
https://doaj.org/article/fca024e70a5d44539208b1da65fe11cc
Autor:
Cristóbal Almendros, Francisco J. M. Mojica, César Díez-Villaseñor, Noemí M. Guzmán, Jesús García-Martínez
Publikováno v:
mBio, Vol 5, Iss 1 (2014)
ABSTRACT Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (cas) genes constitute the CRISPR-Cas systems found in the Bacteria and Archaea domains. At least in some strains they provide an efficient barrier agai
Externí odkaz:
https://doaj.org/article/e4e78c03f7be467899448aa86a25a7c1
Autor:
Belen Esquerra‐Ruvira, Ignacio Baquedano, Raul Ruiz, Almudena Fernandez, Lluis Montoliu, Francisco J. M. Mojica
Publikováno v:
Microbial Biotechnology.
Non-coding RNAs (crRNAs) produced from clustered regularly interspaced short palindromic repeats (CRISPR) loci and CRISPR-associated (Cas) proteins of the prokaryotic CRISPR-Cas systems form complexes that interfere with the spread of transmissible g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e49fc850d2e0fd40042bb80da658658c
https://doi.org/10.1111/1751-7915.14266
https://doi.org/10.1111/1751-7915.14266
Autor:
Borja Alonso-Lerma, Ylenia Jabalera, Sara Samperio, Matias Morin, Almudena Fernandez, Logan T. Hille, Rachel A. Silverstein, Ane Quesada-Ganuza, Antonio Reifs, Sergio Fernández-Peñalver, Yolanda Benitez, Lucia Soletto, Jose A. Gavira, Adrian Diaz, Wim Vranken, Avencia Sanchez-Mejias, Marc Güell, Francisco J. M. Mojica, Benjamin P. Kleinstiver, Miguel A. Moreno-Pelayo, Lluis Montoliu, Raul Perez-Jimenez
Publikováno v:
Nat Microbiol
Clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas9 is an effector protein that targets invading DNA and plays a major role in the prokaryotic adaptive immune system. Although Streptococcus pyogenes CRISPR–Cas9 has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a53d8df2c46392fb5741544f0f76fd3d
https://doi.org/10.1038/s41564-022-01265-y
https://doi.org/10.1038/s41564-022-01265-y
Autor:
Oscar, Salgado, Sergio, Guajardo-Leiva, Ana, Moya-Beltrán, Carla, Barbosa, Christina, Ridley, Javier, Tamayo-Leiva, Raquel, Quatrini, Francisco J M, Mojica, Beatriz, Díez
The Cas1 protein is essential for the functioning of CRISPR-Cas adaptive systems. However, despite the high prevalence of CRISPR-Cas systems in thermophilic microorganisms, few studies have investigated the occurrence and diversity of Cas1 across hot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c94d52a86c811eafbbf22696291537c
https://hdl.handle.net/10045/130086
https://hdl.handle.net/10045/130086
Publikováno v:
International Microbiology
RUA. Repositorio Institucional de la Universidad de Alicante
Universidad de Alicante (UA)
RUA. Repositorio Institucional de la Universidad de Alicante
Universidad de Alicante (UA)
A long time has passed since regularly interspaced DNA repeats were discovered in prokaryotes. Today, those enigmatic repetitive elements termed clustered regularly interspaced short palindromic repeats (CRISPR) are acknowledged as an emblematic part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53456adef01e4b7f140f577a8c20ede7
https://doi.org/10.1007/s10123-021-00208-7
https://doi.org/10.1007/s10123-021-00208-7
Autor:
Philippe Horvath, Česlovas Venclovas, David R. Cheng, Feng Zhang, Daniel H. Haft, Sergey Shmakov, Yuri I. Wolf, Emmanuelle Charpentier, Stan J. J. Brouns, Sylvain Moineau, Winston X. Yan, Virginijus Siksnys, Malcolm F. White, Michael P. Terns, Francisco J. M. Mojica, Shiraz A. Shah, Omer S. Alkhnbashi, Eugene V. Koonin, Roger A. Garrett, Jaime Iranzo, David Scott, Alexander F. Yakunin, Rodolphe Barrangou, John van der Oost, Rolf Backofen, Kira S. Makarova
Publikováno v:
RUA. Repositorio Institucional de la Universidad de Alicante
Universidad de Alicante (UA)
Makarova, K S, Wolf, Y I, Iranzo, J, Shmakov, S A, Alkhnbashi, O S, Brouns, S J J, Charpentier, E, Cheng, D, Haft, D H, Horvath, P, Moineau, S, Mojica, F J M, Scott, D, Shah, S A, Siksnys, V, Terns, M P, Venclovas, Č, White, M F, Yakunin, A F, Yan, W, Zhang, F, Garrett, R A, Backofen, R, van der Oost, J, Barrangou, R & Koonin, E V 2020, ' Evolutionary classification of CRISPR-Cas systems : a burst of class 2 and derived variants ', Nature Reviews. Microbiology, vol. 18, pp. 67-83 . https://doi.org/10.1038/s41579-019-0299-x
Nat Rev Microbiol
Nature Reviews Microbiology, 18, 67-83
Nature Reviews Microbiology 18 (2020)
Universidad de Alicante (UA)
Makarova, K S, Wolf, Y I, Iranzo, J, Shmakov, S A, Alkhnbashi, O S, Brouns, S J J, Charpentier, E, Cheng, D, Haft, D H, Horvath, P, Moineau, S, Mojica, F J M, Scott, D, Shah, S A, Siksnys, V, Terns, M P, Venclovas, Č, White, M F, Yakunin, A F, Yan, W, Zhang, F, Garrett, R A, Backofen, R, van der Oost, J, Barrangou, R & Koonin, E V 2020, ' Evolutionary classification of CRISPR-Cas systems : a burst of class 2 and derived variants ', Nature Reviews. Microbiology, vol. 18, pp. 67-83 . https://doi.org/10.1038/s41579-019-0299-x
Nat Rev Microbiol
Nature Reviews Microbiology, 18, 67-83
Nature Reviews Microbiology 18 (2020)
The number and diversity of known CRISPR–Cas systems have substantially increased in recent years. Here, we provide an updated evolutionary classification of CRISPR–Cas systems and cas genes, with an emphasis on the major developments that have o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cce78d031229e83206ad0cdc202de35f
https://doi.org/10.1038/s41579-019-0299-x
https://doi.org/10.1038/s41579-019-0299-x
Autor:
Inmaculada Garcia-Heredia, Ana-Belen Martin-Cuadrado, Francisco J M Mojica, Fernando Santos, Alex Mira, Josefa Antón, Francisco Rodriguez-Valera
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33802 (2012)
BACKGROUND: Metaviriomes, the viral genomes present in an environment, have been studied by direct sequencing of the viral DNA or by cloning in small insert libraries. The short reads generated by both approaches make it very difficult to assemble an
Externí odkaz:
https://doaj.org/article/b8cbb4e0829a41b9a7c8e48911bcbda6