Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Francisco J. González-Rico"'
Liver regeneration after partial hepatectomy is improved in the absence of aryl hydrocarbon receptor
Autor:
Claudia M. Rejano-Gordillo, Francisco J. González-Rico, Beatriz Marín-Díaz, Ana Ordiales-Talavero, Ana Nacarino-Palma, Ángel C. Román, Jaime M. Merino, Pedro M. Fernández-Salguero
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract The liver is among the few organs having the ability to self-regenerate in response to a severe damage compromising its functionality. The Aryl hydrocarbon receptor (Ahr) is a transcription factor relevant for the detoxification of xenobioti
Externí odkaz:
https://doaj.org/article/9c1c382cfec64853a9458bdb939a35a0
Autor:
Claudia Rejano-Gordillo, Ana Ordiales-Talavero, Ana Nacarino-Palma, Jaime M. Merino, Francisco J. González-Rico, Pedro M. Fernández-Salguero
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Transcription factor aryl hydrocarbon receptor (AHR) has emerged as one of the main regulators involved both in different homeostatic cell functions and tumor progression. Being a member of the family of basic-helix-loop-helix (bHLH) transcriptional
Externí odkaz:
https://doaj.org/article/5d6188d03a7744bda9c345cb48a8ab3c
Autor:
Francisco J. González-Rico, Cristina Vicente-García, Almudena Fernández, Diego Muñoz-Santos, Lluís Montoliu, Antonio Morales-Hernández, Jaime M. Merino, Angel-Carlos Román, Pedro M. Fernández-Salguero
Publikováno v:
Epigenetics & Chromatin, Vol 13, Iss 1, Pp 1-13 (2020)
Abstract Transcriptional repression of Nanog is an important hallmark of stem cell differentiation. Chromatin modifications have been linked to the epigenetic profile of the Nanog gene, but whether chromatin organization actually plays a causal role
Externí odkaz:
https://doaj.org/article/434edba6cc424458a09bce6320a68889
Autor:
Claudia M. Rejano-Gordillo, Beatriz Marín-Díaz, Ana Ordiales-Talavero, Jaime M. Merino, Francisco J. González-Rico, Pedro M. Fernández-Salguero
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14919 (2022)
The aryl hydrocarbon receptor (AHR) is a markedly established regulator of a plethora of cellular and molecular processes. Its initial role in the detoxification of xenobiotic compounds has been partially overshadowed by its involvement in homeostati
Externí odkaz:
https://doaj.org/article/686c4fc6665d44209d1c8ab89fd05408
Autor:
Ana Nacarino-Palma, Claudia M. Rejano-Gordillo, Francisco J. González-Rico, Ana Ordiales-Talavero, Ángel C. Román, Myriam Cuadrado, Xosé R. Bustelo, Jaime M. Merino, Pedro M. Fernández-Salguero
Publikováno v:
Cancers, Vol 13, Iss 16, p 4071 (2021)
Non-small cell lung adenocarcinoma (NSCLC) bearing K-RasG12D mutations is one of the most prevalent types of lung cancer worldwide. Aryl hydrocarbon receptor (AHR) expression varies in human lung tumors and has been associated with either increased o
Externí odkaz:
https://doaj.org/article/5f8e5394845e4a9692ca5a9ebd11126e
Autor:
Eva M. Rico-Leo, Nuria Moreno-Marín, Francisco J. González-Rico, Eva Barrasa, Cristina Ortega-Ferrusola, Patricia Martín-Muñoz, Luis O. Sánchez-Guardado, Elena Llano, Alberto Alvarez-Barrientos, Ascensión Infante-Campos, Inmaculada Catalina-Fernández, Matías Hidalgo-Sánchez, Dirk G. de Rooij, Alberto M. Pendás, Fernando J. Peña, Jaime M. Merino, Pedro M. Fernández-Salguero
Publikováno v:
Open Biology, Vol 6, Iss 12 (2016)
Previous studies suggested that the aryl hydrocarbon receptor (AhR) contributes to mice reproduction and fertility. However, the mechanisms involved remain mostly unknown. Retrotransposon silencing by Piwi-interacting RNAs (piRNAs) is essential for g
Externí odkaz:
https://doaj.org/article/477a439f0e0e40e4a76278073e1b59c0
Autor:
Ana Nacarino-Palma, Pedro M. Fernández-Salguero, Jaime M. Merino, Francisco J. González-Rico, Claudia M. Rejano-Gordillo, Ana Ordiales-Talavero
Publikováno v:
Stem Cell Reports
Summary Mammalian embryogenesis is a complex process controlled by transcription factors that regulate the balance between pluripotency and differentiation. Transcription factor aryl hydrocarbon receptor (AhR) regulates OCT4/POU5F1 and NANOG, both es
Autor:
Ana Nacarino-Palma, Eva M. Rico-Leo, Judith Campisi, Arvind Ramanathan, Francisco J. González-Rico, Claudia M. Rejano-Gordillo, Ana Ordiales-Talavero, Jaime M. Merino, Pedro M. Fernández-Salguero
Publikováno v:
Aging. 14(10)
Aging impairs organismal homeostasis leading to multiple pathologies. Yet, the mechanisms and molecular intermediates involved are largely unknown. Here, we report that aged aryl hydrocarbon receptor-null mice (
Autor:
Angel-Carlos Roman, Diego Muñoz-Santos, Francisco J. González-Rico, Cristina Vicente-García, Antonio Morales-Hernández, Lluis Montoliu, Almudena Fernández, Pedro M. Fernández-Salguero, Jaime M. Merino
Publikováno v:
Epigenetics & Chromatin, Vol 13, Iss 1, Pp 1-13 (2020)
Epigenetics & Chromatin
Digital.CSIC. Repositorio Institucional del CSIC
instname
Epigenetics & Chromatin
Digital.CSIC. Repositorio Institucional del CSIC
instname
© The Author(s) 2020.
Transcriptional repression of Nanog is an important hallmark of stem cell differentiation. Chromatin modifications have been linked to the epigenetic profile of the Nanog gene, but whether chromatin organization actually p
Transcriptional repression of Nanog is an important hallmark of stem cell differentiation. Chromatin modifications have been linked to the epigenetic profile of the Nanog gene, but whether chromatin organization actually p
Autor:
Myriam Cuadrado, Ana Ordiales-Talavero, Francisco J. González-Rico, Ana Nacarino-Palma, Claudia M. Rejano-Gordillo, Angel Carlos Roman, Xosé R. Bustelo, Pedro M. Fernández-Salguero, Jaime M. Merino
Publikováno v:
Cancers
Volume 13
Issue 16
Cancers, Vol 13, Iss 4071, p 4071 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Volume 13
Issue 16
Cancers, Vol 13, Iss 4071, p 4071 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Non-small cell lung adenocarcinoma (NSCLC) bearing K-RasG12D mutations is one of the most prevalent types of lung cancer worldwide. Aryl hydrocarbon receptor (AHR) expression varies in human lung tumors and has been associated with either increased o