Generation of human immortalized chondrocytes from osteoarthritic and healthy cartilage a new tool for cartilage pathophysiology studies

Autor: María Piñeiro-Ramil, Clara Sanjurjo-Rodríguez, Silvia Rodríguez-Fernández, Tamara Hermida-Gómez, Francisco J. Blanco-García, Isaac Fuentes-Boquete, Carlos Vaamonde-García, Silvia Díaz-Prado

Publikováno v: Bone & Joint Research, Vol 12, Iss 1, Pp 46-57 (2023)

AimsAfter a few passages of in vitro culture, primary human articular chondrocytes undergo senescence and loss of their phenotype. Most of the available chondrocyte cell lines have been obtained from cartilage tissues different from diarthrodial join

Externí odkaz: https://doaj.org/article/312a3eaeac5d45eb917aa2300523847e

Generation of Mesenchymal Cell Lines Derived from Aged Donors

Autor: María Piñeiro-Ramil, Clara Sanjurjo-Rodríguez, Silvia Rodríguez-Fernández, Rocío Castro-Viñuelas, Tamara Hermida-Gómez, Francisco J. Blanco-García, Isaac Fuentes-Boquete, Silvia Díaz-Prado

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 19, p 10667 (2021)

Background: Mesenchymal stromal cells (MSCs) have the capacity for self-renewal and multi-differentiation, and for this reason they are considered a potential cellular source in regenerative medicine of cartilage and bone. However, research on this f

Externí odkaz: https://doaj.org/article/fcdb37d37f9b4a05bd1ca4710588f2ed

Precision medicine: something is changing in rheumatology

Autor: Francisco J, Blanco-García

Publikováno v: Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria. 44(6)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b31c736b894c41a564eab8cebaef4f8f
https://pubmed.ncbi.nlm.nih.gov/33156743

Expert Recommendations on the Interleukin 6 Blockade in Patients with Rheumatoid Arthritis

Autor: Hèctor Corominas, Sagrario Bustabad, Antonio Fernández Nebro, José Andrés Román Ivorra, Raimon Sanmartí, Jesús Tornero Molina, Ricardo Blanco Alonso, Jaime Calvo Alén, Francisco J. Blanco García, Alejandro Balsa Criado

Publikováno v: Reumatologia Clinica
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname

OBJECTIVE: To draft recommendations on interleukin 6 (IL-6) blockade in rheumatoid arthritis (RA), based on best evidence and experience.; METHODS: A group of 10 experts on IL-6 blockade in RA was selected. The 2 coordinators formulated 23 questions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec5a1cf30c250ed3c670467f466cb45c
https://pubmed.ncbi.nlm.nih.gov/30098882

Lipoprotein(A) Concentrations In Rheumatoid Arthritis On Biologic Therapy: Results From The Cardiovascular In Rheumatology [Carma] Study Project

Autor: Manuela Sianes Fernández, Pablo Mesa del Castillo, Mercedes Morcillo, Isabel Labiano Bastero, Emilio Giner Serret, Javier del Pino, Cesar magro, Javier Rivera Redondo, Esperanza Naredo, Ramón Huguet Codina, María D. Fábregas, Daniel Pielfort Garrido, Beatriz González Alvarez, José M. Aramburu, Luis María Jiménez, Jose Gonzalez, Eduardo Collantes, Beatriz Yoldi, César Díaz, Enrique Júdez Navarro, Encarnación Pagán, Ivan Castellví, Javier R. Godo, José Santos-Rey, Antonio Fernández Nebro, Joan Maymó, María Luz García Vivar, Fernando Jimenez Zorzo, Raimon Sanmartí, Olga Martínez-González, Mercedes Ramentol, Claudia Murillo, Sergio Antonio Rodríguez Montero, Javier Calvo, Javier Llorca, Jordi Fiter, Chesús Beltrán Audera, Cayetano Alegre De Miquel, Gabriela Ávila, Antonio López Meseguer, Jaime Calvo Alen, Rosario García de Vicuña, Miriam García Arias, Marta Medrano, Joan M. Nolla, Trinidad Pérez Sandoval, G Salvador, Sagrario Bustabad, José Antonio Pinto-Tasende, María José Galindo, Eugenio Chamizo-Carmona, José García Torón, Ma Dolores Beteta Fernández, Ramón Valls, María A. Martín-Martínez, Pilar Morales, Francisco J. Blanco García, José M. Moreno, Teresa González Hernández, María Ángeles García Morales, Laura Cebrián Méndez, Antonio Atanes Sandoval, Isabel Rotés, Javier García González, Félix Francisco, Isabel Mateo, Indalecio Monteagudo, Maria Angeles Belmonte López, Manel Pujol, Estefanía Quesada-Masachs, Inmaculada Ros, Fernando Sánchez-Alonso, Ma José Moreno Martínez, Santos Castañeda, Ana Turrión, Juan Carlos Quevedo, Federico Díaz-González, Ruth López González, Estefanía Moreno, Esmeralda Delgado, Ana Ruibal Escribano, Carlos González-Juanatey, Sergio Ros Expósito, Pilar Font, Cristina Fernández Carballido, Francisco J. González Polo, Francisco J. López Longo, Alba Erra, Tatiana Cobo-Ibáñez, Carmen O. Sánchez González, Jesús Alberto García Vadillo, Olga Maiz, Montserrat Romera-Baurés, Gloria García Consuegra, Carmen Barbadillo, Virginia Ruiz, María Bonet, Jesús Babío Herráez, Dolores Fábregas-Canales, Antonio J. Mas, Ana Cruz, Miren Uriarte-Ecenarro, M.V. Irigoyen, Sara Marsal Barril, I. Ureña, Yolanda María León, Oscar Fontseré Patón, Alejandro Muñoz, Ángela Pecondón, Javier Bachiller, Pilar Espiño, Eva Revuelta Evrard, Miriam Amirall, Luis F. Linares, María Dolores Sánchez González, Ana Nieto, Benjamín Fernández Gutiérrez, Martina Steiner, Sara Manrique-Arija, María Luisa González Gómez, Carlos González Fernández, Inmaculada Bañegil, Dolors Grado, María J. González Fernández, Carlos Rodríguez Lozano, Cruz Fernández Espartero, Ingrid Möller, Eugenia Gonzalez de Rábago, Amalia Rueda, María P. Moreno Gil, Luis Espadaler, María Pilar Lis Bona, Inmaculada Jiménez, Julia Fernández Melón, Eugenio Giménez Ubeda, Isabel Rodríguez, C. Erausquin, Natividad Oreiro Villar, Raúl Menor Almagro, Rebeca Belmonte Gómez, Jesús Tornero-Molina, Ángel María García Aparicio, Horacio Berman, Enrique Raya, María Teresa Navío, Francisco J. Manero, Silvia Martínez Pardo, Joaquín Belzunegui, José M. Senabre, Manel Riera, Julio Sánchez, María Enriqueta Peiró, Jesús Marzo Gracía, Mónica Ibáñez, Natalia A. Rivera, J. Carlos Fernández López, Santiago Muñoz, Carmen García-Gómez, José C. Rosas, Ginés Sánchez Nievas, Elena Alonso Blanco Morales, Alberto Cantabrana, Manuel J. Moreno, Soledad Ojeda, Silvia Iniesta Escolano, Desireé Ruíz, Gema Bonilla, Antonio Zea, Carla Lannuzzelli Barroso, Pastora Granados Bautista, Luis Carreño, Francisco J. Navarro Blasco, José A. Piqueras, José A. Miranda-Filloy, Sonia Cabrera, Lydia Abasolo, Natalia Palmou, Virginia Coret Cagigal, Estefania Moreno Ruzafa, Alfonso Corrales, Silvia Sánchez Serrano, Delia Gerona, Miguel A. González-Gay, Elena Riera Alonso, Juana Sampedro Alvarez, Fernando Gamero, Azucena Hernández Sanz, Olaia Fernández Berrizbeitia

Publikováno v: Journal of Clinical Lipidology (2017), Volume 11, Issue 3, May-June 2017, Pages 749-756.e3
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)

Background Plasma concentrations of lipoprotein (a) (Lp(a)), a lipoprotein with atherogenic and thrombogenic properties, have a strong genetic basis, although high concentrations of Lp(a) have also been reported in the context of inflammation, as in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f74e5194aebeb6a0a063a08988f549c2
http://hdl.handle.net/10902/12093