IRF4 and IRGs Delineate Clinically Relevant Gene Expression Signatures in Systemic Lupus Erythematosus and Rheumatoid Arthritis

Autor: Javier Rodríguez-Carrio, Patricia López, Mercedes Alperi-López, Luis Caminal-Montero, Francisco J. Ballina-García, Ana Suárez

Publikováno v: Frontiers in Immunology, Vol 9 (2019)

Introduction: Overactivation of the type I interferon (IFN) signature has been observed in several systemic autoimmune conditions, such as Systemic Lupus Erythematosus (SLE) or Rheumatoid Arthritis (RA). Impaired control of Interferon-Responding Gene

Externí odkaz: https://doaj.org/article/6b575e203a994a16b261c3d810e28aff

Heterogeneity of the Type I Interferon Signature in Rheumatoid Arthritis: A Potential Limitation for Its Use As a Clinical Biomarker

Autor: Javier Rodríguez-Carrio, Mercedes Alperi-López, Patricia López, Francisco J. Ballina-García, Ana Suárez

Publikováno v: Frontiers in Immunology, Vol 8 (2018)

IntroductionAn increased expression of interferon (IFN)-responding genes (IRGs), the so-called IFN signature, has been reported in rheumatoid arthritis (RA). However, some controversy exists concerning its clinical relevance. The main aim of this stu

Externí odkaz: https://doaj.org/article/7a2662684d644e30b21d0d334095ba15

GlycA Levels during the Earliest Stages of Rheumatoid Arthritis: Potential Use as a Biomarker of Subclinical Cardiovascular Disease

Autor: Miriam Gil-Serret, Lorena Benavente, Francisco J. Ballina-García, Catalina Ulloa, Ana Suárez, M. Alperi-López, Javier Rodríguez-Carrio, Ángel I. Pérez-Álvarez, Patricia López, Núria Amigó

Publikováno v: Journal of Clinical Medicine
Volume 9
Issue 8
WOS:000568182300001
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Journal of Clinical Medicine, Vol 9, Iss 2472, p 2472 (2020)
RUO: Repositorio Institucional de la Universidad de Oviedo
Universidad de Oviedo (UNIOVI)

This study aimed at evaluating the clinical relevance of glycoprotein profiles during the earliest phases of rheumatoid arthritis (RA) as biomarkers of cardiovascular (CV) risk and treatment response. Then, GlycA and GlycB serum levels were measured

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::946495e517a3d79bcb70586c368b6269

THU0111 ANGIOGENIC T CELLS AS AN INDEPENDENT PREDICTOR OF VASCULAR STIFFNESS IN VERY EARLY RHEUMATOID ARTHRITIS

Autor: Lorena Benavente, Javier Rodríguez-Carrio, Mercedes Alperi-López, Ana Suárez, Ángel I. Pérez-Álvarez, Francisco J. Ballina-García, Patricia López

Publikováno v: Poster Presentations.

Background Angiogenic T cells (Tang) are responsible of vascular repair and homeostasis. Decreased Tang frequencies have been reported in rheumatoid arthritis (RA), in association with disease activity and previous history of cardiovascular (CV) dise

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::52c8093c70b854f809bb18ae986be2f1
https://doi.org/10.1136/annrheumdis-2019-eular.2647

AB0775 EFFECTIVENESS AND SAFETY OF USTEKINUMAB 90 IN PATIENTS WITH PSORIATIC ARTHRITIS.REAL WORLD EVIDENCE STUDY

Autor: Sara Alonso Castro, Estefanía Pardo Campo, José Andrés Lorenzo Martín, Francisco J. Ballina-García, Rubén Queiro Silva, Mercedes Alperi-López, Luis Marcelino Arboleya Rodríguez, Lilyan Consuelo Charca Benavente

Publikováno v: Abstracts accepted for Publication.

Background: Ustekinumab (UST) is a drug with proven efficacy in two randomized clinical trials in psoriatic arthritis -PsA- (PSUMMIT I and II). The data from these trials suggest that the 90 mg dose may be better than the 45 mg dose. Studies real wor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2973d2700084869e039b8001ef11eee4
https://doi.org/10.1136/annrheumdis-2019-eular.8186