Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Francisco J Ortega"'
Autor:
Nuria Mallorquí-Bagué, Ana B Fagundo, Susana Jimenez-Murcia, Rafael de la Torre, Rosa M Baños, Cristina Botella, Felipe F Casanueva, Ana B Crujeiras, Jose C Fernández-García, Jose M Fernández-Real, Gema Frühbeck, Roser Granero, Amaia Rodríguez, Iris Tolosa-Sola, Francisco J Ortega, Francisco J Tinahones, Eva Alvarez-Moya, Cristian Ochoa, Jose M Menchón, Fernando Fernández-Aranda
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163901 (2016)
INTRODUCTION:Addictions are associated with decision making impairments. The present study explores decision making in Substance use disorder (SUD), Gambling disorder (GD) and Obesity (OB) when assessed by Iowa Gambling Task (IGT) and compares them w
Externí odkaz:
https://doaj.org/article/b4982958df7a46d7a8eee2fcba027462
Autor:
Aina Lluch, Jèssica Latorre, Núria Oliveras-Cañellas, Ana Fernández-Sánchez, José M. Moreno-Navarrete, Anna Castells-Nobau, Ferran Comas, Maria Buxò, José I. Rodríguez-Hermosa, María Ballester, Isabel Espadas, Alejandro Martín-Montalvo, Birong Zhang, You Zhou, Ralph Burkhardt, Marcus Höring, Gerhard Liebisch, Ainara Castellanos-Rubio, Izortze Santin, Asha Kar, Markku Laakso, Päivi Pajukanta, Vesa M. Olkkonen, José M. Fernández-Real, Francisco J. Ortega
Publikováno v:
Molecular Metabolism, Vol 90, Iss , Pp 102040- (2024)
Background: Long non-coding RNAs (lncRNAs) can perform tasks of key relevance in fat cells, contributing, when defective, to the burden of obesity and its sequelae. Here, scrutiny of adipose tissue transcriptomes before and after bariatric surgery (G
Externí odkaz:
https://doaj.org/article/ca620d31a1364335831107541b0e2f56
Autor:
Neus Pueyo, Francisco J Ortega, Josep M Mercader, José M Moreno-Navarrete, Monica Sabater, Sílvia Bonàs, Patricia Botas, Elías Delgado, Wifredo Ricart, María T Martinez-Larrad, Manuel Serrano-Ríos, David Torrents, José M Fernández-Real
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60468 (2013)
CONTEXT: Surfactant protein-D (SP-D) is a primordial component of the innate immune system intrinsically linked to metabolic pathways. We aimed to study the association of single nucleotide polymorphisms (SNPs) affecting SP-D with insulin resistance
Externí odkaz:
https://doaj.org/article/d31ba94b88b8407b85acaccc9d1e4da4
Autor:
Francisco J Ortega, José M Moreno-Navarrete, Dolores Mayas, Eva García-Santos, María Gómez-Serrano, José I Rodriguez-Hermosa, Bartomeu Ruiz, Wifredo Ricart, Francisco J Tinahones, Gema Frühbeck, Belen Peral, José M Fernández-Real
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e33233 (2012)
CONTEXT: Expression and activity of the main lipogenic enzymes is paradoxically decreased in obesity, but the mechanisms behind these findings are poorly known. Breast Cancer 1 (BrCa1) interacts with acetyl-CoA carboxylase (ACC) reducing the rate of
Externí odkaz:
https://doaj.org/article/7ba185e10c294f73b2e20f897c901e65
Autor:
Rafael Pérez-Pérez, Juan A López, Eva García-Santos, Emilio Camafeita, María Gómez-Serrano, Francisco J Ortega-Delgado, Wifredo Ricart, José M Fernández-Real, Belén Peral
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30326 (2012)
Protein expression studies based on the two major intra-abdominal human fat depots, the subcutaneous and the omental fat, can shed light into the mechanisms involved in obesity and its co-morbidities. Here we address, for the first time, the identifi
Externí odkaz:
https://doaj.org/article/b10b85db5ebf4d01ba50221d922bff41
Autor:
Francisco J Ortega, José M Moreno-Navarrete, Gerard Pardo, Monica Sabater, Manuela Hummel, Anna Ferrer, Jose I Rodriguez-Hermosa, Bartomeu Ruiz, Wifredo Ricart, Belen Peral, José M Fernández-Real
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9022 (2010)
BACKGROUND: Potential regulators of adipogenesis include microRNAs (miRNAs), small non-coding RNAs that have been recently shown related to adiposity and differentially expressed in fat depots. However, to date no study is available, to our knowledge
Externí odkaz:
https://doaj.org/article/aadbce41ca69404a9350768d4aed311a
Autor:
Aina Lluch, Jessica Latorre, Angela Serena-Maione, Isabel Espadas, Estefanía Caballano-Infantes, José M. Moreno-Navarrete, Núria Oliveras-Cañellas, Wifredo Ricart, María M. Malagón, Alejandro Martin-Montalvo, Walter Birchmeier, Witold Szymanski, Johannes Graumann, María Gómez-Serrano, Elena Sommariva, José M. Fernández-Real, Francisco J. Ortega
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Plakophilin-2 (PKP2) is a key component of desmosomes, which, when defective, is known to promote the fibro-fatty infiltration of heart muscle. Less attention has been given to its role in adipose tissue. We report here that levels of PKP2 s
Externí odkaz:
https://doaj.org/article/c9aab534331a4f3fa90b32b90c48e65f
Autor:
Abdulbasit Amin, Marina Badenes, Johanna Tüshaus, Érika de Carvalho, Emma Burbridge, Pedro Faísca, Květa Trávníčková, André Barros, Stefania Carobbio, Pedro M. Domingos, Antonio Vidal-Puig, Luís F. Moita, Sarah Maguire, Kvido Stříšovský, Francisco J. Ortega, José Manuel Fernández-Real, Stefan F. Lichtenthaler, Colin Adrain
Publikováno v:
Molecular Metabolism, Vol 73, Iss , Pp 101731- (2023)
Objective: The metalloprotease ADAM17 (also called TACE) plays fundamental roles in homeostasis by shedding key signaling molecules from the cell surface. Although its importance for the immune system and epithelial tissues is well-documented, little
Externí odkaz:
https://doaj.org/article/05555155e4744951844c5a7be30e9720
Autor:
Aina Lluch, Sonia R. Veiga, Jèssica Latorre, José M. Moreno-Navarrete, Núria Bonifaci, Van Dien Nguyen, You Zhou, Marcus Höring, Gerhard Liebisch, Vesa M. Olkkonen, David Llobet-Navas, George Thomas, Ruth Rodríguez-Barrueco, José M. Fernández-Real, Sara C. Kozma, Francisco J. Ortega
Publikováno v:
JCI Insight, Vol 7, Iss 14 (2022)
The ribosomal protein S6 kinase 1 (S6K1) is a relevant effector downstream of the mammalian target of rapamycin complex 1 (mTORC1), best known for its role in the control of lipid homeostasis. Consistent with this, mice lacking the S6k1 gene have a d
Externí odkaz:
https://doaj.org/article/fd58ace89a53441583d2cf1df43a3a08
Publikováno v:
ACS Omega, Vol 3, Iss 6, Pp 6617-6623 (2018)
Externí odkaz:
https://doaj.org/article/871cf7d637a74f289c12ffed64bc3894