Zobrazeno 1 - 10
of 339
pro vyhledávání: '"Francisco J, Esteva"'
Publikováno v:
The Lancet Regional Health. Americas, Vol 32, Iss , Pp 100712- (2024)
Summary: Background: Understanding the survival outcomes associated with breast-conserving therapy (BCT) and mastectomy after preoperative systemic therapy (PST) enables clinicians to provide more personalized treatment recommendations. However, lack
Externí odkaz:
https://doaj.org/article/c6ff81558cca4cf8937cb01a0e2a20d9
Publikováno v:
Cancer Reports, Vol 6, Iss 8, Pp n/a-n/a (2023)
Abstract Background Because of the phenomenal success of treatment with monoclonal antibodies and antibody‐drug conjugates targeting human epidermal growth factor receptor 2 (HER2), most patients with early‐stage HER2‐positive breast cancer (HE
Externí odkaz:
https://doaj.org/article/5a03b990f5b24a6b803f3604a3ac0466
Autor:
Peter A. Fasching, J. Thaddeus Beck, Arlene Chan, Michele De Laurentiis, Francisco J. Esteva, Guy Jerusalem, Patrick Neven, Xavier Pivot, Giulia V. Bianchi, Miguel Martin, David Chandiwana, Brad Lanoue, Antonia Ridolfi, Yingbo Wang, Karen Rodriguez Lorenc, Arnd Nusch
Publikováno v:
Breast, Vol 54, Iss , Pp 148-154 (2020)
Purpose: In the MONALEESA-3 Phase III trial of patients with hormone receptor–positive human epidermal growth factor receptor–negative advanced breast cancer, ribociclib plus fulvestrant significantly improved progression-free survival (PFS) and
Externí odkaz:
https://doaj.org/article/a5b481e9a0e5458182d897e58fbb782f
Publikováno v:
Cancer Reports.
Autor:
Komal Jhaveri, Rui Wang, Eleonora Teplinsky, Sarat Chandarlapaty, David Solit, Karen Cadoo, James Speyer, Gabriella D’Andrea, Sylvia Adams, Sujata Patil, Sofia Haque, Tara O’Neill, Kent Friedman, Francisco J. Esteva, Clifford Hudis, Shanu Modi
Publikováno v:
Breast Cancer Research, Vol 19, Iss 1, Pp 1-8 (2017)
Abstract Background Targeted therapies in HER2-positive metastatic breast cancer significantly improve outcomes but efficacy is limited by therapeutic resistance. HER2 is an acutely sensitive Heat Shock Protein 90 (HSP90) client and HSP90 inhibition
Externí odkaz:
https://doaj.org/article/78b6e8d4c26b4748b7167315c71133ec
Autor:
Eddy S. Yang, Susan E. Nozell, Albert F. LoBuglio, Rachel Schiff, C. Kent Osborne, Francisco J. Esteva, Andres Forero, Ling Zeng, Tiffiny S. Cooper, Rajani Rajbhandari, Zhuo Zhang, Monica E. Wielgos
Supplemental Methods and Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c5a8b57cc45d1d222f8d418e134855
https://doi.org/10.1158/1535-7163.22505158
https://doi.org/10.1158/1535-7163.22505158
Autor:
James M. Reuben, Massimo Cristofanilli, Francisco J. Esteva, Sendurai A. Mani, Sabino De Placido, Naoto T. Ueno, Vicente Valero, Ricardo H. Alvarez, Charla A. Parker, Michele De Laurentiis, Sanda Tin, Bang-Ning Lee, Michal Mego, Evan Cohen, Simone Anfossi, Hui Gao, Antonio Giordano
PDF file - 64K, Gene expression levels of EMT-TFs in the tested cell lines (HMLE, HMLE-TWIST, MCF-7, BT-474, SKBR-3, MDA-MB-231)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::614a28cc4dd719936feab0907317e570
https://doi.org/10.1158/1535-7163.22496455
https://doi.org/10.1158/1535-7163.22496455
Autor:
James M. Reuben, Massimo Cristofanilli, Francisco J. Esteva, Sendurai A. Mani, Sabino De Placido, Naoto T. Ueno, Vicente Valero, Ricardo H. Alvarez, Charla A. Parker, Michele De Laurentiis, Sanda Tin, Bang-Ning Lee, Michal Mego, Evan Cohen, Simone Anfossi, Hui Gao, Antonio Giordano
PDF file - 86K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be1c93d3bfa4125aaaaabf799d4cc52
https://doi.org/10.1158/1535-7163.22496452.v1
https://doi.org/10.1158/1535-7163.22496452.v1
Autor:
James M. Reuben, Massimo Cristofanilli, Francisco J. Esteva, Sendurai A. Mani, Sabino De Placido, Naoto T. Ueno, Vicente Valero, Ricardo H. Alvarez, Charla A. Parker, Michele De Laurentiis, Sanda Tin, Bang-Ning Lee, Michal Mego, Evan Cohen, Simone Anfossi, Hui Gao, Antonio Giordano
Currently, there is extensive information about circulating tumor cells (CTC) and their prognostic value; however, little is known about other characteristics of these cells. In this prospective study, we assessed the gene transcripts of epithelial-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14907bb695b18bdad63e76e969214945
https://doi.org/10.1158/1535-7163.c.6535276.v1
https://doi.org/10.1158/1535-7163.c.6535276.v1
Autor:
Eddy S. Yang, Susan E. Nozell, Albert F. LoBuglio, Rachel Schiff, C. Kent Osborne, Francisco J. Esteva, Andres Forero, Ling Zeng, Tiffiny S. Cooper, Rajani Rajbhandari, Zhuo Zhang, Monica E. Wielgos
SFigure1: HER2+ breast cancer cells are sensitive to nirparib SFigure2: HER2+ breast cancer microtumors are sensitive to ABT-888 SFigure3: (A) ABT-888 reduces PAR levels in HER2+ xenograft models. (B) ABT-888 did not cause weight loss in mice SFigure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::304cc460640481e9f8fa3bf07cd6c7b4
https://doi.org/10.1158/1535-7163.22505161.v1
https://doi.org/10.1158/1535-7163.22505161.v1