Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Francisco H. Cruzalegui"'
Autor:
Stéphane Depil, Francisco H. Cruzalegui, John A. Hickman, Alain Pierré, Jean-Claude Ortuno, Alex Cordi, Jean A. Boutin, Brian P. Lockhart, Paolo M. Comoglio, Anne Jacquet-Bescond, Valérie Cattan, François Bouzom, Georges Da Violante, Gilles Ferry, Stéphane Léonce, Alain Bruno, Imre Fejes, Carine Saunier, Céline J. Bossard, Mike F. Burbridge
Pharmacokinetic parameters of S49076 administered orally to female balb/c nu/nu mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16d85780489a7d5f2f98bfaf00e0d717
https://doi.org/10.1158/1535-7163.22500580.v1
https://doi.org/10.1158/1535-7163.22500580.v1
Autor:
Stéphane Depil, Francisco H. Cruzalegui, John A. Hickman, Alain Pierré, Jean-Claude Ortuno, Alex Cordi, Jean A. Boutin, Brian P. Lockhart, Paolo M. Comoglio, Anne Jacquet-Bescond, Valérie Cattan, François Bouzom, Georges Da Violante, Gilles Ferry, Stéphane Léonce, Alain Bruno, Imre Fejes, Carine Saunier, Céline J. Bossard, Mike F. Burbridge
Aberrant activity of the receptor tyrosine kinases MET, AXL, and FGFR1/2/3 has been associated with tumor progression in a wide variety of human malignancies, notably in instances of primary or acquired resistance to existing or emerging anticancer t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::430099b575997bc84c21ebae598114d2
https://doi.org/10.1158/1535-7163.c.6536506.v1
https://doi.org/10.1158/1535-7163.c.6536506.v1
Autor:
Stéphane Depil, Francisco H. Cruzalegui, John A. Hickman, Alain Pierré, Jean-Claude Ortuno, Alex Cordi, Jean A. Boutin, Brian P. Lockhart, Paolo M. Comoglio, Anne Jacquet-Bescond, Valérie Cattan, François Bouzom, Georges Da Violante, Gilles Ferry, Stéphane Léonce, Alain Bruno, Imre Fejes, Carine Saunier, Céline J. Bossard, Mike F. Burbridge
Western blot detection of total and phosphorylated MET, AXL, FGFR1/2/3 and phosphorylated FRS2 in cell lines and tumor xenografts used in the study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::123135a315fe10245d8747481cf1d27a
https://doi.org/10.1158/1535-7163.22500589
https://doi.org/10.1158/1535-7163.22500589
Autor:
Stéphane Depil, Francisco H. Cruzalegui, John A. Hickman, Alain Pierré, Jean-Claude Ortuno, Alex Cordi, Jean A. Boutin, Brian P. Lockhart, Paolo M. Comoglio, Anne Jacquet-Bescond, Valérie Cattan, François Bouzom, Georges Da Violante, Gilles Ferry, Stéphane Léonce, Alain Bruno, Imre Fejes, Carine Saunier, Céline J. Bossard, Mike F. Burbridge
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2531d2864ca4243b46130be353d490da
https://doi.org/10.1158/1535-7163.22500592.v1
https://doi.org/10.1158/1535-7163.22500592.v1
Autor:
Stéphane Depil, Francisco H. Cruzalegui, John A. Hickman, Alain Pierré, Jean-Claude Ortuno, Alex Cordi, Jean A. Boutin, Brian P. Lockhart, Paolo M. Comoglio, Anne Jacquet-Bescond, Valérie Cattan, François Bouzom, Georges Da Violante, Gilles Ferry, Stéphane Léonce, Alain Bruno, Imre Fejes, Carine Saunier, Céline J. Bossard, Mike F. Burbridge
Kinase interaction map for S49076 at 100 nM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::205dbfd47ef91e9858162252f06c4b82
https://doi.org/10.1158/1535-7163.22500586
https://doi.org/10.1158/1535-7163.22500586
Publikováno v:
ResearcherID
Elk-1, a member of the TCF family of Ets domain proteins, contains a C-terminal transcriptional activation domain with multiple copies of the MAPK core consensus sequence S/T-P. This region is phosphorylated by MAP kinases in vitro and in vivo, but t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::644bd01d69ae80806818c0be2a20c12c
https://doi.org/10.1038/sj.onc.1203362
https://doi.org/10.1038/sj.onc.1203362
Publikováno v:
Neuron. 22:789-798
Recruitment of the coactivator CBP by signal-regulated transcription factors and stimulation of CBP activity are key regulatory events in the induction of gene transcription following Ca 2+ flux through ligand- and/or voltage-gated ion channels in hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db8fc551ce562a6ffd3a6060815cdac1
https://doi.org/10.1016/s0896-6273(00)80737-0
https://doi.org/10.1016/s0896-6273(00)80737-0
Publikováno v:
Cell Calcium. 23:131-134
Nuclear calcium is an important regulator of gene expression following membrane depolarisation of electrically excitable cells. Here we describe nuclear calcium transients in hippocampal neurons following activation of calcium influx through L-type v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3afd8e543413934611882c74736a1369
https://doi.org/10.1016/s0143-4160(98)90111-7
https://doi.org/10.1016/s0143-4160(98)90111-7
Publikováno v:
Journal of Biological Chemistry. 268:26171-26178
We have expressed the rat brain Ca2+/calmodulin (CaM)-dependent protein kinase type IV in insect cells. The recombinant enzyme is produced as a single polypeptide that migrates on SDS-polyacrylamide gel electrophoresis at 61 kDa. Recombinant CaM kina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::911df9621e00903b2cbcdf9155016075
https://doi.org/10.1016/s0021-9258(19)74296-3
https://doi.org/10.1016/s0021-9258(19)74296-3
Autor:
Jean-Claude Cavadore, Marcel Dorée, Jean Mery, Thierry Lorca, Didier Fesquet, Francisco H. Cruzalegui, Anthony R. Means
Publikováno v:
Nature. 366:270-273
In vertebrates, unfertilized eggs are arrested at second meiotic metaphase by a cytostatic factor (CSF), an essential component of which is the product of the c-mos proto-oncogene. CSF prevents ubiquitin-dependent degradation of mitotic cyclins and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a6a9a9382b091dd3d520134702f3a73
https://doi.org/10.1038/366270a0
https://doi.org/10.1038/366270a0