Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Francisco Gutiérrez Agüera"'
Autor:
Pablo Menendez, Diego Sánchez Martínez, Néstor Tirado, Sofia Mensurado, Alba Martínez-Moreno, Paola Romecín, Francisco Gutiérrez Agüera, Daniel V Correia, Bruno Silva-Santos
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 9 (2022)
Background Chimeric antigen receptor (CAR)-T cells have emerged as a breakthrough treatment for relapse/refractory hematological tumors, showing impressive complete remission rates. However, around 50% of the patients relapse before 1-year post-treat
Externí odkaz:
https://doaj.org/article/edb66f0a03c24fde95b09459aa6c9b05
Autor:
Pablo Menendez, Maria Castella, Pedro Marín, Alex Bataller, Jordi Esteve, Diego Sánchez Martínez, Francisco Gutiérrez Agüera, Heleia Roca Ho, Clara Bueno, Matteo Libero Baroni, Talia Velasco Hernandez, Rafael Diaz de la Guardia, Julio Castaño, Eduardo Anguita, Susana Vives, Josep Nomdedeu, Helene Lapillone, Anne E Bras, Vincent H J van der Velden, Jordi Junca, Binje Vick, Irmela Jeremias, Angel Lopez, Marc Sorigue
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Background Acute myeloid leukemia (AML) is a hematopoietic malignancy which is biologically, phenotypically and genetically very heterogeneous. Outcome of patients with AML remains dismal, highlighting the need for improved, less toxic therapies. Chi
Externí odkaz:
https://doaj.org/article/b180785a65d94e76b264b5d5407bd47b
Autor:
Talia Velasco-Hernandez, Juan L. Trincado, Meritxell Vinyoles, Adria Closa, Francisco Gutiérrez-Agüera, Oscar Molina, Virginia C Rodríguez-Cortez, Paolo Petazzi, Sergi Beneyto-Calabuig, Lars Velten, Paola Romecin, Raquel Casquero, Fernando Abollo-Jiménez, Rafael Díaz de la Guardia, Patricia Lorden, Alex Bataller, Helene Lapillonne, Ronald W Stam, Susana Vives, Montserrat Torrebadell, Jose Luis Fuster, Clara Bueno, Eduardo Eyras, Holger Heyn, Pablo Menéndez
Relapse remains a major challenge in the clinical management of acute myeloid leukemia (AML), and is driven by rare therapy-resistant leukemia-initiating stem cells (LSCs) that reside in specific bone marrow niches. Hypoxia signaling keeps cells in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::233f655448b4557cf4775c9ba90d673d
https://doi.org/10.1101/2022.03.02.482638
https://doi.org/10.1101/2022.03.02.482638
Autor:
Diego Sánchez-Martínez, Néstor Tirado, Sofia Mensurado, Alba Martínez-Moreno, Paola Romecin, Francisco Gutiérrez-Agüera, Daniel V Correia, Bruno Silva-Santos, Pablo Menéndez
Publikováno v:
Journal for ImmunoTherapy of Cancer
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
Chimeric Antigen Receptor (CAR)-T cells have emerged as a breakthrough treatment for relapse/refractory (r/r) hematological tumors, showing impressive complete remission rates in B-cell malignancies. However, around 50% of the patients relapse before
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::517c8dba5b2943b1abb1d46c5c4b7d67
https://fundanet.igtp.cat/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=7328
https://fundanet.igtp.cat/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=7328
Autor:
Simon Sedej, Torsten Bloch Rasmussen, Fernando Domínguez, Jose Maria Garcia-Aznar, Jesús Vázquez, Ana Briceño, Jesús Piqueras-Flores, Jorge Alegre-Cebollada, Giovanna Giovinazzo, Elías Herrero-Galán, Enrique Calvo, Carmen Suay-Corredera, David Giganti, Mahmoud Abdellatif, Juan A. Bernal, Inmaculada Vivo-Ortega, Francisco Gutiérrez-Agüera, Natalia Vicente, Belén Bornstein, Esther Gonzalez-Lopez, Thomas Morris Hey, Enrique Lara-Pezzi, Diana Velázquez-Carreras, Peter P. Rainer, Ángel Fernández-Trasancos, Laura Lalaguna, Belén Prados, Inés Martínez-Martín, Raul Perez-Jimenez, Pablo García-Pavía, Juan Pablo Ochoa, Claudio Badía Careaga, Maria Rosaria Pricolo, Elena Bonzón-Kulichenko, Marta Cobo-Marcos, Cristina Sánchez-González
The protein titin determines cardiomyocyte contraction and truncating variants in the titin gene (TTN) are the most common cause of dilated cardiomyopathy (DCM). Different to truncations, missense variants inTTNare currently classified as variants of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c2571241a29bddee113f7f8e5cf49fd
https://doi.org/10.1101/2020.09.05.282913
https://doi.org/10.1101/2020.09.05.282913
Autor:
Talia Velasco‐Hernandez, Juan L. Trincado, Meritxell Vinyoles, Adria Closa, Alba Martínez‐Moreno, Francisco Gutiérrez‐Agüera, Oscar Molina, Virginia C. Rodríguez‐Cortez, Pau Ximeno‐Parpal, Narcís Fernández‐Fuentes, Paolo Petazzi, Sergi Beneyto‐Calabuig, Lars Velten, Paola Romecin, Raquel Casquero, Fernando Abollo‐Jiménez, Rafael D. de laGuardia, Patricia Lorden, Alex Bataller, Hélène Lapillonne, Ronald W. Stam, Susana Vives, Montserrat Torrebadell, Jose L. Fuster, Clara Bueno, Jean‐Emmanuel Sarry, Eduardo Eyras, Holger Heyn, Pablo Menéndez
Publikováno v:
HemaSphere, Vol 8, Iss 2, Pp n/a-n/a (2024)
Abstract Relapse remains a major challenge in the clinical management of acute myeloid leukemia (AML) and is driven by rare therapy‐resistant leukemia stem cells (LSCs) that reside in specific bone marrow niches. Hypoxia signaling maintains cells i
Externí odkaz:
https://doaj.org/article/5cf2e9d9f3b0488ebf1aab0a7234b697
Autor:
Diego Sánchez‐Martínez, Francisco Gutiérrez‐Agüera, Paola Romecin, Meritxell Vinyoles, Marta Palomo, Néstor Tirado, Samanta Romina Zanetti, Manel Juan, Michela Carlet, Irmela Jeremias, Pablo Menéndez
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 2, Pp n/a-n/a (2021)
Abstract CD19‐directed chimeric antigen receptors (CAR) T cells induce impressive rates of complete response in advanced B‐cell malignancies, specially in B‐cell acute lymphoblastic leukemia (B‐ALL). However, CAR T‐cell‐treated patients e
Externí odkaz:
https://doaj.org/article/ffe207600ed44e63a58632d940d7630c
Autor:
Clara Bueno, Fernando J Calero-Nieto, Xiaonan Wang, Rafael Valdés-Mas, Francisco Gutiérrez-Agüera, Heleia Roca-Ho, Veronica Ayllon, Pedro J Real, David Arambilet, Lluis Espinosa, Raul Torres-Ruiz, Antonio Agraz-Doblas, Ignacio Varela, Jasper de Boer, Anna Bigas, Bertie Gottgens, Rolf Marschalek, Pablo Menendez
Publikováno v:
Haematologica, Vol 104, Iss 6 (2019)
The t(4;11)(q21;q23) translocation is associated with high-risk infant pro-B-cell acute lymphoblastic leukemia and arises prenatally during embryonic/fetal hematopoiesis. The developmental/pathogenic contribution of the t(4;11)-resulting MLL-AF4 (MA4
Externí odkaz:
https://doaj.org/article/c6cca9f1e10144babdafb62ac067bf29
Autor:
Rafael Diaz de la Guardia, Belen Lopez-Millan, Heleia Roca-Ho, Clara Bueno, Francisco Gutiérrez-Agüera, Jose Luis Fuster, Eduardo Anguita, Samanta Romina Zanetti, Susana Vives, Josep Nomdedeu, Robert Sackstein, Jessie Lavoie, Elena Gónzalez-Rey, Mario Delgado, Michael Rosu-Myles, Pablo Menendez
Publikováno v:
Haematologica, Vol 104, Iss 2 (2019)
Externí odkaz:
https://doaj.org/article/5ca09c1c4466411dbf3ba0df1a71aada