Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Francisco Barajas‐Olmos"'
Autor:
Pablo Iruzubieta, César Augusto Pinheiro Ferreira Alves, Aisha M. Al Shamsi, Gehad ElGhazali, Maha S. Zaki, Lorenzo Pinelli, Diego Lopergolo, Bernard P.H. Cho, Amy A. Jolly, Amna Al Futaisi, Fatema Al-Amrani, Jessica Galli, Elisa Fazzi, Katarina Vulin, Francisco Barajas-Olmos, Holger Hengel, Bayan Mohammed Aljamal, Vahideh Nasr, Farhad Assarzadegan, Michele Ragno, Luigi Trojano, Naomi Meave Ojeda, Arman Çakar, Silvia Bianchi, Francesca Pescini, Anna Poggesi, Amal Al Tenalji, Majid Aziz, Rahema Mohammad, Aziza Chedrawi, Nicola De Stefano, Giovanni Zifarelli, Ludger Schöls, Tobias B. Haack, Adriana Rebelo, Stephan Zuchner, Filiz Koc, Lyn R. Griffiths, Lorena Orozco, Karla García Helmes, Meisam Babaei, Peter Bauer, Won Chan Jeong, Ehsan Ghayoor Karimiani, Miriam Schmidts, Joseph G. Gleeson, Wendy K. Chung, Fowzan Sami Alkuraya, Bita Shalbafan, Hugh S. Markus, Henry Houlden, Reza Maroofian
Publikováno v:
EBioMedicine, Vol 107, Iss , Pp 105297- (2024)
Summary: Background: NOTCH3 encodes a transmembrane receptor critical for vascular smooth muscle cell function. NOTCH3 variants are the leading cause of hereditary cerebral small vessel disease (SVD). While monoallelic cysteine-involving missense var
Externí odkaz:
https://doaj.org/article/dcf457b6550e45488640bb16d06d46d7
Autor:
Namibia Guadalupe Mendiola-Vidal, Cecilia Contreras-Cubas, Francisco Barajas-Olmos, José Rafael Villafan-Bernal, Ana Lucia Yañez-Felix, Humberto García-Ortiz, Federico Centeno-Cruz, Elvia Mendoza-Caamal, Carmen Alaez-Verson, Juan Luis Jiménez-Ruíz, Tulia Monge-Cázares, Esther Lieberman, Vicente Baca, José Luis Lezana, Angélica Martínez-Hernández, Lorena Orozco
Publikováno v:
Life, Vol 14, Iss 11, p 1445 (2024)
Cystic fibrosis (CF) is a rare autosomal recessive disease most commonly affecting the Caucasian population. CF diagnosis can be a challenge due to the large spectrum of pathogenic variants in the CFTR gene and the effects of complex alleles. Next-ge
Externí odkaz:
https://doaj.org/article/781e1e7ecace456495f72d1528c97948
Autor:
Monserrat I. Morales-Rivera, Radamés Alemón-Medina, Angélica Martínez-Hernández, Cecilia Contreras-Cubas, Nelly F. Altamirano-Bustamante, Josefina Gómez-Garduño, Elvia C. Mendoza-Caamal, J. Orlando Nuñez-González, Raquel García-Álvarez, Cristina Revilla-Monsalve, José Antonio Valcarcel-Gamiño, José Rafael Villafan-Bernal, Federico Centeno-Cruz, Humberto García-Ortiz, Francisco Barajas-Olmos, Lorena Orozco
Publikováno v:
Pharmaceuticals, Vol 17, Iss 10, p 1385 (2024)
Background: Type 2 diabetes (T2D) is one of the leading causes of mortality and is a public health challenge worldwide. Metformin is the first-choice treatment for T2D; its pharmacokinetics (PK) is facilitated by members of the solute carrier (SLC) s
Externí odkaz:
https://doaj.org/article/8ddd17748e0345d0be4dbf504ebcd0ca
Autor:
Angélica Martínez-Hernández, Elvia C. Mendoza-Caamal, Namibia G. Mendiola-Vidal, Francisco Barajas-Olmos, José Rafael Villafan-Bernal, Juan Luis Jiménez-Ruiz, Tulia Monge-Cazares, Humberto García-Ortiz, Cecilia Contreras- Cubas, Federico Centeno-Cruz, Carmen Alaez-Verson, Soraya Ortega-Torres, Adriana del C. Luna-Castañeda, Vicente Baca, José Luis Lezana, Lorena Orozco
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e28984- (2024)
Background: Molecular diagnosis of cystic fibrosis (CF) is challenging in Mexico due to the population's high genetic heterogeneity. To date, 46 pathogenic variants (PVs) have been reported, yielding a detection rate of 77%. We updated the spectrum a
Externí odkaz:
https://doaj.org/article/ce4c8142ceb54ebeaeeec00442c786a9
Autor:
Paulina Baca, Francisco Barajas-Olmos, Elaheh Mirzaeicheshmeh, Carlos Zerrweck, Lizbeth Guilbert, Ernesto Carlos Sánchez, Marlen Flores-Huacuja, Rafael Villafán, Angélica Martínez-Hernández, Humberto García-Ortiz, Cecilia Contreras-Cubas, Federico Centeno-Cruz, Lorena Orozco
Publikováno v:
Nutrition & Diabetes, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract Background Obesity is accompanied by excess adipose fat storage, which may lead to adipose dysfunction, insulin resistance, and type 2 diabetes (T2D). Currently, the tendency to develop T2D in obesity cannot be explained by genetic variation
Externí odkaz:
https://doaj.org/article/45ecd549e2fe42ed8da35d7f81b5b55d
Autor:
Cecilia Contreras-Cubas, Francisco Barajas-Olmos, Maria Inés Frayre-Martínez, Georgina Siordia-Reyes, Claudia C. Guízar-Sánchez, Humberto García-Ortiz, Lorena Orozco, Vicente Baca
Publikováno v:
BMC Medical Genomics, Vol 15, Iss 1, Pp 1-8 (2022)
Abstract Background Dysferlinopathy encompasses a group of rare muscular dystrophies caused by recessive mutations in the DYSF gene. The phenotype ranges from asymptomatic elevated serum creatine kinase (hyperCKemia) to selective and progressive invo
Externí odkaz:
https://doaj.org/article/1d8e4ff88a6045b3bef64e041e839b46
Autor:
Mirna Edith Morales-Marín, Xochitl Helga Castro Martínez, Federico Centeno Cruz, Francisco Barajas-Olmos, Omar Náfate López, Amalia Guadalupe Gómez Cotero, Lorena Orozco, Humberto Nicolini Sánchez
Publikováno v:
Brain Sciences, Vol 13, Iss 10, p 1420 (2023)
The etiology of Autism Spectrum Disorders (ASD) is a result of the interaction between genes and the environment. The study of epigenetic factors that affect gene expression, such as DNA methylation, has become an important area of research in ASD. I
Externí odkaz:
https://doaj.org/article/90a490f9c0304012a44790f05b59a676
Autor:
Humberto García-Ortiz, Francisco Barajas-Olmos, Marlen Flores-Huacuja, Monserrat I. Morales-Rivera, Angélica Martínez-Hernández, Vicente Baca, Cecilia Contreras-Cubas, Lorena Orozco
Publikováno v:
Frontiers in Medicine, Vol 9 (2023)
ObjectiveHere we aimed to investigate the association of the Xq28 risk haplotype (H1) with susceptibility to childhood-onset systemic lupus erythematosus (SLE), and to compare its frequency and genetic structure in the Mexican population with those i
Externí odkaz:
https://doaj.org/article/8b62430afbe34f46aa3878d9b9209a33
Autor:
Humberto García-Ortiz, Francisco Barajas-Olmos, Cecilia Contreras-Cubas, Miguel Ángel Cid-Soto, Emilio J. Córdova, Federico Centeno-Cruz, Elvia Mendoza-Caamal, Isabel Cicerón-Arellano, Marlen Flores-Huacuja, Paulina Baca, Deborah A. Bolnick, Meradeth Snow, Silvia Esperanza Flores-Martínez, Rocio Ortiz-Lopez, Austin W. Reynolds, Antonio Blanchet, Mirna Morales-Marín, Rafael Velázquez-Cruz, Aleksandar David Kostic, Carlos Galaviz-Hernández, Alejandra Guadalupe García-Zapién, José Concepción Jiménez-López, Guadalupe León-Reyes, Eva Gabriela Salas-Bautista, Blanca Patricia Lazalde-Ramos, Juan Luis Jiménez-Ruíz, Guadalupe Salas-Martínez, Jazmín Ramos-Madrigal, Elaheh Mirzaeicheshmeh, Yolanda Saldaña-Alvarez, María del Carmen Abrahantes-Pérez, Francisco Loeza-Becerra, Raúl Mojica-Espinosa, Federico Sánchez-Quinto, Héctor Rangel-Villalobos, Martha Sosa-Macías, José Sánchez-Corona, Augusto Rojas-Martinez, Angélica Martínez-Hernández, Lorena Orozco
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Indigenous populations, including in those in Mexico are underrepresented in genetic studies. Here, the authors perform a population genetics study of indigenous peoples in Mexico to explore demographic histories of the region in the context of geogr
Externí odkaz:
https://doaj.org/article/c86ceb211f3846cf9fd37b70fafef48a
Autor:
Wendoline Anaya-Morua, José Rafael Villafan-Bernal, Esther Ramírez-Moreno, Humberto García-Ortiz, Raigam Jafet Martínez-Portilla, Cecilia Contreras-Cubas, Angélica Martínez-Hernández, Federico Centeno-Cruz, Florencia Estefana Pedroza-Montoya, Lorena Orozco, Francisco Barajas-Olmos
Publikováno v:
Antioxidants, Vol 12, Iss 8, p 1512 (2023)
The total antioxidant capacity (TAC) has been related to the development of and complications associated with chronic diseases, but its importance during obesity is not entirely clear. We conducted a systematic review and meta-analysis to clarify whe
Externí odkaz:
https://doaj.org/article/51c8d04836fd49098707473de527de6a