Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Francisco Antequera"'
Autor:
Alicia García, Laura Durán, Mar Sánchez, Sara González, Rodrigo Santamaría, Francisco Antequera
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113605- (2024)
Summary: Despite the symmetrical structure of nucleosomes, in vitro studies have shown that transcription proceeds with different efficiency depending on the orientation of the DNA sequence around them. However, it is unclear whether this functional
Externí odkaz:
https://doaj.org/article/75d51a40174e4e3d97626f15fdd078f6
Autor:
Philippe Materne, Enrique Vázquez, Mar Sánchez, Carlo Yague-Sanz, Jayamani Anandhakumar, Valerie Migeot, Francisco Antequera, Damien Hermand
Publikováno v:
eLife, Vol 5 (2016)
In fission yeast, the ste11 gene encodes the master regulator initiating the switch from vegetative growth to gametogenesis. In a previous paper, we showed that the methylation of H3K4 and consequent promoter nucleosome deacetylation repress ste11 in
Externí odkaz:
https://doaj.org/article/9ff5496c85fb4db0b921ddde5f33d784
Autor:
Philippe Materne, Jayamani Anandhakumar, Valerie Migeot, Ignacio Soriano, Carlo Yague-Sanz, Elena Hidalgo, Carole Mignion, Luis Quintales, Francisco Antequera, Damien Hermand
Publikováno v:
eLife, Vol 4 (2015)
The phosphorylation of the RNA polymerase II C-terminal domain (CTD) plays a key role in delineating transcribed regions within chromatin by recruiting histone methylases and deacetylases. Using genome-wide nucleosome mapping, we show that CTD S2 pho
Externí odkaz:
https://doaj.org/article/7766f9965c0843ab9fec4418e90c464f
Publikováno v:
Open Biology, Vol 5, Iss 4 (2015)
Nucleosomes are the basic structural units of chromatin. Most of the yeast genome is organized in a pattern of positioned nucleosomes that is stably maintained under a wide range of physiological conditions. In this work, we have searched for sequenc
Externí odkaz:
https://doaj.org/article/c2d722b97f01470a8031d4342b2363f2
Autor:
Juan Carlos Cañas, María Luisa García-Rubio, Alicia García, Francisco Antequera, Belén Gómez-González, Andrés Aguilera
The stability of the genome is occasionally challenged by the formation of DNA-RNA hybrids and R-loops, which can be influenced by the chromatin context. This is mainly due to the fact that DNA-RNA hybrids hamper the progression of replication forks,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19de121d623c4ffe6a172574e3fdfcb7
https://hdl.handle.net/10668/19782
https://hdl.handle.net/10668/19782
Autor:
Facundo Ramos, Laura Durán, Mar Sánchez, Adrián Campos, David Hernández-Villamor, Francisco Antequera, Andrés Clemente-Blanco
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Homologous recombination is essential to maintain genome stability in response to DNA damage. Here, we have used genome-wide sequencing to quantitatively analyze at nucleotide resolution the dynamics of DNA end resection, re-synthesis, and gene conve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f1e23da39d3ab795c19e92a12714101
https://pubmed.ncbi.nlm.nih.gov/35021102
https://pubmed.ncbi.nlm.nih.gov/35021102
Autor:
Francisco Antequera
Publikováno v:
eLS
Methylated CpG dinucleotides at position 5 of cytosine are associated with transcriptional repression and an inactive chromatin conformation in mammals. CpG islands are nonmethylated, CpG-rich regions of ∼1 kb that represent approximately 1% of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1640f7959390dda9fb4c93ee702a6f3c
https://doi.org/10.1002/9780470015902.a0005027.pub3
https://doi.org/10.1002/9780470015902.a0005027.pub3
Autor:
Mohammad M. Karimi, Jonay García-Luis, Mar Sánchez, Luis Aragón, Luciana Lazar-Stefanita, Pilar Gutiérrez-Escribano, Adam Jarmuz, Axel Cournac, Alicia García, Alex Montoya, Sara Serrate González, Francisco Antequera, Holger B. Kramer, Marian Dore, Agnès Thierry, Romain Koszul
Publikováno v:
Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, 2019, 26 (10), pp.970-979. ⟨10.1038/s41594-019-0307-x⟩
Nature Structural & Molecular Biology
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Structural and Molecular Biology, Nature Publishing Group, 2019, 26 (10), pp.970-979. ⟨10.1038/s41594-019-0307-x⟩
Nature structural & molecular biology
Nature Structural and Molecular Biology, 2019, 26 (10), pp.970-979. ⟨10.1038/s41594-019-0307-x⟩
Nature Structural & Molecular Biology
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Structural and Molecular Biology, Nature Publishing Group, 2019, 26 (10), pp.970-979. ⟨10.1038/s41594-019-0307-x⟩
Nature structural & molecular biology
Cohesin is a regulator of genome architecture with roles in sister chromatid cohesion and chromosome compaction. The recruitment and mobility of cohesin complexes on DNA is restricted by nucleosomes. Here, we show that the role of cohesin in chromoso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff873f2a495cde66beec1322917ac14
https://hal-pasteur.archives-ouvertes.fr/pasteur-02866764
https://hal-pasteur.archives-ouvertes.fr/pasteur-02866764
Autor:
Marian Dore, Pilar Gutiérrez-Escribano, Alicia García, Francisco Antequera, Jonay García-Luis, Romain Koszul, Luciana Lazar-Stefanita, Adam Jarmuz, Mohammad M. Karimi, Luis Aragón, Agnès Thierry, Alex Montoya, Mar Sánchez, Holger B. Kramer, Sara Serrate González
Cohesin is a key regulator of genome architecture with roles in sister chromatid cohesion 1,2 and the organisation of higher-order structures during interphase 3 and mitosis 4,5. The recruitment and mobility of cohesin complexes on DNA is restricted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa3a0306cf15a0114e1eaa9a97eebbe
https://doi.org/10.1101/756601
https://doi.org/10.1101/756601
Publikováno v:
Current Genetics
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
The occupancy of nucleosomes governs access to the eukaryotic genomes and results from a combination of biophysical features and the effect of ATP-dependent remodelling complexes. Most promoter regions show a conserved pattern characterized by a nucl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aebbb5ac6d6c34abbdb8c1f24eafc8d
http://europepmc.org/articles/PMC5383693
http://europepmc.org/articles/PMC5383693