Zobrazeno 1 - 10
of 227
pro vyhledávání: '"Francisco Amado"'
Autor:
João Valente-Santos, Rui Vitorino, Cláudia Sousa-Mendes, Paula Oliveira, Bruno Colaço, Ana I. Faustino-Rocha, Maria João Neuparth, Adelino Leite-Moreira, José Alberto Duarte, Rita Ferreira, Francisco Amado
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 550 (2023)
The salivary glands play a central role in the secretion of saliva, whose composition and volume affect oral and overall health. A lesser-explored dimension encompasses the possible changes in salivary gland proteomes in response to fluctuations in s
Externí odkaz:
https://doaj.org/article/04a6cb7ddad7494b891c7bc705798ebe
Autor:
Giulia Guadalupi, Cristina Contini, Federica Iavarone, Massimo Castagnola, Irene Messana, Gavino Faa, Simona Onali, Luchino Chessa, Rui Vitorino, Francisco Amado, Giacomo Diaz, Barbara Manconi, Tiziana Cabras, Alessandra Olianas
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12207 (2023)
Autoimmune hepatitis (AIH) and primary biliary cholangitis (PBC) are autoimmune liver diseases that target the liver and have a wide spectrum of presentation. A global overview of quantitative variations on the salivary proteome in presence of these
Externí odkaz:
https://doaj.org/article/8328c860e48349d7b03dbd94a760e430
Autor:
Carina Bernardo, Fátima L. Monteiro, Inês Direito, Francisco Amado, Vera Afreixo, Lúcio L. Santos, Luisa A. Helguero
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
BackgroundEstrogen receptors alpha (ERα) and beta (ERβ) and the cooperating protein GATA-binding factor 3 (GATA3) have been implicated in bladder carcinogenesis and tumour progression. GATA3 and ER have been functionally linked in the establishment
Externí odkaz:
https://doaj.org/article/1d9946fdd24a437c833bda0c152b4021
Autor:
Alexandra Moreira-Pais, Rita Nogueira-Ferreira, Stephanie Reis, Susana Aveiro, António Barros, Tânia Melo, Bárbara Matos, José Alberto Duarte, Fernanda Seixas, Pedro Domingues, Francisco Amado, Margarida Fardilha, Paula A. Oliveira, Rita Ferreira, Rui Vitorino
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7560 (2022)
Prostate cancer (PCa) is one of the most lethal diseases in men, which justifies the search for new diagnostic tools. The aim of the present study was to gain new insights into the progression of prostate carcinogenesis by analyzing the urine proteom
Externí odkaz:
https://doaj.org/article/34301cf0258e44289bfc96e58451feb2
Autor:
Fábio Trindade, António S. Barros, Jéssica Silva, Antonia Vlahou, Inês Falcão-Pires, Sofia Guedes, Carla Vitorino, Rita Ferreira, Adelino Leite-Moreira, Francisco Amado, Rui Vitorino
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5940 (2021)
Native biofluid peptides offer important information about diseases, holding promise as biomarkers. Particularly, the non-invasive nature of urine sampling, and its high peptide concentration, make urine peptidomics a useful strategy to study the pat
Externí odkaz:
https://doaj.org/article/ce91675109444d63b7e0d52ade5eb282
Autor:
Lénia Rodrigues, Rosa Espanca, Ana Rodrigues Costa, Célia Miguel Antunes, Clarinda Pomar, Fernando Capela-Silva, Cristina Conceição Pinheiro, Francisco Amado, Elsa Lamy
Publikováno v:
Journal of Nutrition and Metabolism, Vol 2017 (2017)
The satiety inducing hormone leptin acts not only at central nervous system but also at peripheral level. Leptin receptors are found in several sense related organs, including the mouth. A role of leptin in sweet taste response has been suggested but
Externí odkaz:
https://doaj.org/article/12c2109d459f4c2aa45a549a2bb58d4e
Autor:
Luis, Perpetuo, Rita, Ferreira, Visith, Thongboonkerd, Sofia, Guedes, Francisco, Amado, Rui, Vitorino
Publikováno v:
Advances in clinical chemistry. 111
Exosomes are tiny membrane-enveloped vesicles of endosomal origin, typically 40-120nm in diameter, produced by most cells in both normal and pathological situations. These exosomes can be isolated from all biofluids, including urine. In this context,
Publikováno v:
Cellular and Molecular Life Sciences. 78:3265-3283
Exosomes are involved in a wide variety of biochemical processes in human body homeostasis. Exosomes also provide important information regarding communications among several organ systems. Additionally, they can serve as molecular vehicles to delive
Autor:
Rui Vitorino, Luís Perpétuo, Visith Thongboonkerd, Rita Ferreira, Sofia Guedes, Francisco Amado
Publikováno v:
Current proteinpeptide science. 23(11)
Background: Exosome research is a current trend in functional proteomics as it provides im-portant data on the pathophysiology and pathogenesis of diseases. The scientific outputs re-garding these topics often only approach disease-protein/peptide/ex