Zobrazeno 1 - 10
of 249
pro vyhledávání: '"Francisco, O'Valle"'
Autor:
Javier Moleón, Cristina González-Correa, Iñaki Robles-Vera, Sofía Miñano, Néstor de la Visitación, Antonio Manuel Barranco, Natividad Martín-Morales, Francisco O’Valle, Laura Mayo-Martínez, Antonia García, Marta Toral, Rosario Jiménez, Miguel Romero, Juan Duarte
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTThis study is to investigate whether dietary fiber intake prevents vascular and renal damage in a genetic mouse model of systemic lupus erythematosus (SLE), and the contribution of gut microbiota in the protective effects. Female NZBWF1 (SLE)
Externí odkaz:
https://doaj.org/article/80f6f931713a4a0eae1385f63b15461c
Autor:
Miguel Padial-Molina, Saray Montalvo-Acosta, Natividad Martín-Morales, Virginia Pérez-Carrasco, Antonio Magan-Fernandez, Francisco Mesa, Francisco O’Valle, Jose Antonio Garcia-Salcedo, Pablo Galindo-Moreno
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 961 (2024)
The activation of inflammasomes is thought to induce the inflammatory process around dental implants. No information is available on the correlation between microbiota and inflammasomes in clinical samples from patients suffering peri-implantitis. Fo
Externí odkaz:
https://doaj.org/article/76ef80a110c84404baf5f4e501700275
Autor:
Cristina González-Correa, Javier Moleón, Sofía Miñano, Iñaki Robles-Vera, Marta Toral, Natividad Martín-Morales, Francisco O’Valle, Manuel Sánchez, Manuel Gómez-Guzmán, Rosario Jiménez, Miguel Romero, Juan Duarte
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 158, Iss , Pp 114149- (2023)
Microbiota has a crucial role in the host blood pressure (BP) regulation. The present study analyzes whether the mineralocorticoid receptor antagonist spironolactone ameliorates the dysbiosic state in a genetic model of neurogenic hypertension. Twent
Externí odkaz:
https://doaj.org/article/2af1d588cdc44ba7a0f83cdaba5720b9
Autor:
Sebastián Montoro-Molina, Andrés Quesada, Francisco O’Valle, Natividad Martín Morales, María del Carmen de Gracia, Isabel Rodríguez-Gómez, Antonio Osuna, Rosemary Wangensteen, Félix Vargas
Publikováno v:
Kidney & Blood Pressure Research, Pp 1-12 (2021)
Background: The age-related increase in blood pressure in spontaneously hypertensive rats (SHRs) is associated to cardiac hypertrophy, heart failure, and renal injury. Here, we investigated for the first time the urinary enzymatic activities of gluta
Externí odkaz:
https://doaj.org/article/3e57adfe1e664a51a0a5ee10e00dd92a
Autor:
María Morell, Nieves Varela, Casimiro Castillejo-López, Céline Coppard, María José Luque, Ying-Yu Wu, Natividad Martín-Morales, Francisco Pérez-Cózar, Gonzalo Gómez-Hernández, Ramesh Kumar, Francisco O'Valle, Marta E. Alarcón-Riquelme, Concepción Marañón
Publikováno v:
EBioMedicine, Vol 76, Iss , Pp 103808- (2022)
Summary: Background: Type I IFN (IFN-I) is a family of cytokines involved in the pathogenesis of autoimmune and autoinflammatory diseases such as psoriasis. SIDT1 is an ER-resident protein expressed in the lymphoid lineage, and involved in anti-viral
Externí odkaz:
https://doaj.org/article/b3f6e58340744937ac2a795dc1e33a3c
Autor:
África Martínez-Blanco, Marilú Domínguez-Pantoja, María Botía-Sánchez, Sonia Pérez-Cabrera, Nerea Bello-Iglesias, Paula Carrillo-Rodríguez, Natividad Martin-Morales, Antonio Lario-Simón, María M. Pérez-Sánchez-Cañete, Laura Montosa-Hidalgo, Salvador Guerrero-Fernández, Victoria M. Longobardo-Polanco, Sandra Redondo-Sánchez, Alberto Cornet-Gomez, María Torres-Sáez, Ana Fernández-Ibáñez, Laura Terrón-Camero, Eduardo Andrés-León, Francisco O’Valle, Ramón Merino, Mercedes Zubiaur, Jaime Sancho
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The absence of the mouse cell surface receptor CD38 in Cd38−/− mice suggests that this receptor acts as a positive regulator of inflammatory and autoimmune responses. Here, we report that, in the context of the chronic graft-versus-host disease (
Externí odkaz:
https://doaj.org/article/a00bd329d702410b9ebcd3e172e7f1ee
Autor:
Fernando Cavalcanti, Elena Gonzalez-Rey, Mario Delgado, Clara P. Falo, Leyre Mestre, Carmen Guaza, Francisco O’Valle, Michele M. P. Lufino, Jordi Xaus, Cristina Mascaró, Serena Lunardi, Natalia Sacilotto, Paola Dessanti, David Rotllant, Xavier Navarro, Mireia Herrando-Grabulosa, Carlos Buesa, Tamara Maes
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1420 (2022)
Lysine specific demethylase 1 (LSD1; also known as KDM1A), is an epigenetic modulator that modifies the histone methylation status. KDM1A forms a part of protein complexes that regulate the expression of genes involved in the onset and progression of
Externí odkaz:
https://doaj.org/article/df089ff6678843aa91f71f1d603fc7ce
Autor:
Juan Manuel Martí, Angel Garcia-Diaz, Daniel Delgado-Bellido, Francisco O'Valle, Ariannys González-Flores, Onintza Carlevaris, José Manuel Rodríguez-Vargas, Jean Christophe Amé, Françoise Dantzer, George L. King, Klaudia Dziedzic, Edurne Berra, E. de Álava, A.T. Amaral, Ester M. Hammond, F. Javier Oliver
Publikováno v:
Redox Biology, Vol 41, Iss , Pp 101885- (2021)
Background: The adaptation to hypoxia is mainly controlled by the HIF transcription factors. Increased expression/activity of HIF-1α correlates with poor prognosis in cancer patients. PARP-1 inhibitors are used in the clinic to treat BRCAness breast
Externí odkaz:
https://doaj.org/article/0f826f2e9407497a88ab90c6673c93fa
Autor:
Pablo Galindo‐Moreno, Natividad Martín‐Morales, Allinson Olaechea, Pedro Hernández‐Cortes, Cristobal Verdugo‐Escamilla, Francisca Martinez‐Ruiz, Ana Belen Carrillo‐Galvez, Francisco O'Valle, Miguel Padial‐Molina
Publikováno v:
Clinical Implant Dentistry and Related Research. 25:370-380
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::507123e03f182f215bb179eeb3583738
https://doi.org/10.1111/cid.13184
https://doi.org/10.1111/cid.13184
Autor:
Mónica Fernández‐Cortés, Daniel Delgado‐Bellido, Eloísa Bermúdez‐Jiménez, Jesús M Paramio, Francisco O'Valle, Stefan Vinckier, Peter Carmeliet, Angel Garcia‐Diaz, F Javier Oliver
Publikováno v:
Fernández-Cortés, M, Delgado-Bellido, D, Bermúdez-Jiménez, E, Paramio, J M, O'Valle, F, Vinckier, S, Carmeliet, P, Garcia-Diaz, A & Oliver, F J 2023, ' PARP inhibition promotes endothelial-like traits in melanoma cells and modulates pericyte coverage dynamics during vasculogenic mimicry ', Journal of Pathology, vol. 259, no. 3, pp. 318-330 . https://doi.org/10.1002/path.6043
Vasculogenic mimicry (VM) describes the ability of highly aggressive tumor cells to develop pseudovascular structures without the participation of endothelial cells. PARP1 is implicated in the activation of hypoxia-inducible factors, which are crucia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::044de670cce5af61d066b4dbb34cd688
https://doi.org/10.1002/path.6043
https://doi.org/10.1002/path.6043