Výsledky vyhledávání - "Francisco, Maresca"

Redox Engineering by Ectopic Overexpression of NADH Kinase in Recombinant Pichia pastoris ( Komagataella phaffii ): Impact on Cell Physiology and Recombinant Production of Secreted Proteins

Autor: Francisco Maresca, Màrius Tomàs-Gamisans, Joan Albiol, Cristiane Conte Paim de Andrade, Pau Ferrer, Sergi Monforte

Publikováno v: Applied and Environmental Microbiology. 86

High-level expression and secretion of heterologous proteins in yeast causes an increased energy demand, which may result in altered metabolic flux distributions. Moreover, recombinant protein overproduction often results in ER-stress and oxidative s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2f46109331067d1d1ac0c29e646e4162
https://doi.org/10.1128/aem.02038-19

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Redox Engineering by Ectopic Overexpression of NADH Kinase in Recombinant Pichia pastoris (

Autor: Màrius, Tomàs-Gamisans, Cristiane Conte Paim, Andrade, Francisco, Maresca, Sergi, Monforte, Pau, Ferrer, Joan, Albiol

Publikováno v: Appl Environ Microbiol

High-level expression and secretion of heterologous proteins in yeast cause an increased energy demand, which may result in altered metabolic flux distributions. Moreover, recombinant protein overproduction often results in endoplasmic reticulum (ER)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7cd082ea307f34eebf7bba1bf258bed4
https://pubmed.ncbi.nlm.nih.gov/31757828

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