Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Francisca N'kuli"'
Autor:
Mélanie Carquin, Hélène Pollet, Maria Veiga-da-Cunha, Antoine Cominelli, Patrick Van Der Smissen, Francisca N'kuli, Hervé Emonard, Patrick Henriet, Hideaki Mizuno, Pierre J. Courtoy, Donatienne Tyteca
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 7, Pp 1331-1342 (2014)
We recently reported that trace insertion of exogenous fluorescent (green BODIPY) analogs of sphingomyelin (SM) into living red blood cells (RBCs), partially spread onto coverslips, labels submicrometric domains, visible by confocal microscopy. We he
Externí odkaz:
https://doaj.org/article/52724f4fde7a4b589052dbd7d0888a92
Autor:
Nathalie Pierrot, Donatienne Tyteca, Ludovic D'auria, Ilse Dewachter, Philippe Gailly, Aurélie Hendrickx, Bernadette Tasiaux, Laetitia El Haylani, Nathalie Muls, Francisca N'Kuli, Annie Laquerrière, Jean‐Baptiste Demoulin, Dominique Campion, Jean‐Pierre Brion, Pierre J. Courtoy, Pascal Kienlen‐Campard, Jean‐Noël Octave
Publikováno v:
EMBO Molecular Medicine, Vol 5, Iss 4, Pp 608-625 (2013)
Abstract Perturbation of lipid metabolism favours progression of Alzheimer disease, in which processing of Amyloid Precursor Protein (APP) has important implications. APP cleavage is tightly regulated by cholesterol and APP fragments regulate lipid h
Externí odkaz:
https://doaj.org/article/52729e8d758b461191d5a8239eadf2db
Autor:
Donatienne Tyteca, Tomoya Nishino, Huguette Debaix, Patrick Van Der Smissen, Francisca N'Kuli, Delia Hoffmann, Yvette Cnops, Virginie Rabolli, Geert van Loo, Rudi Beyaert, François Huaux, Olivier Devuyst, Pierre J Courtoy
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117398 (2015)
The water channel aquaporin-1 (AQP1) promotes migration of many cell types. Although AQP1 is expressed in macrophages, its potential role in macrophage motility, particularly in relation with phenotype polarization, remains unknown. We here addressed
Externí odkaz:
https://doaj.org/article/945a74e25259425f9875a968419b6d35
Autor:
Benoit Bilanges, François Jouret, Tongsong Wang, Giuseppina Grieco, Francisca N'Kuli, Pierre J. Courtoy, Patrick Van Der Smissen, Seppo Vainio, Héloïse P. Gaide Chevronnay, Virginie Janssens, Christophe E. Pierreux, Bart Vanhaesebroeck, Jingdong Shan
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Scientific Reports
Scientific Reports
Kidney proximal tubular cells (PTCs) are highly specialized for ultrafiltrate reabsorption and serve as paradigm of apical epithelial differentiation. Vps34/PI3-kinase type III (PI3KC3) regulates endosomal dynamics, macroautophagy and lysosomal funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09fcd14c76ae27eaa434cabb34ed7968
https://doi.org/10.1038/s41598-018-32389-z
https://doi.org/10.1038/s41598-018-32389-z
Autor:
Etienne Marbaix, Donatienne Tyteca, Pascale Lemoine, Antoine Cominelli, Mathias Halbout, Patrick Henriet, Francisca N'Kuli, Pierre J. Courtoy
Publikováno v:
Traffic. 15:401-417
Matrix metalloproteinase-27 (MMP-27) is poorly characterized. Sequence comparison suggests that a C-terminal extension (CTE) includes a potential transmembrane domain as in some membrane-type (MT)-MMPs. Having noticed that MMP-27 was barely secreted,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8093017edd68e2f73a8ef3f2c623101d
https://doi.org/10.1111/tra.12149
https://doi.org/10.1111/tra.12149
Autor:
Giuseppina Grieco, Bart Vanhaesebroeck, Virginie Janssens, Hervé Emonard, Sarah Carpentier, Donatienne Tyteca, Christophe E. Pierreux, Héloïse P. Gaide Chevronnay, Patrick Van Der Smissen, Francisca N'Kuli, Benoit Bilanges, Pierre J. Courtoy
Publikováno v:
Traffic. 14:933-948
Recycling is a limiting step for receptor-mediated endocytosis. We first report three in vitro or in vivo evidences that class III PI3K/VPS34 is the key PI3K isoform regulating apical recycling. A substractive approach, comparing in Opossum Kidney (O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5141edd9180e164da4b558589c1dd53e
https://doi.org/10.1111/tra.12079
https://doi.org/10.1111/tra.12079
Autor:
Marc Witcher, Pierre J. Courtoy, Jess G. Thoene, Thomas J. Goss, Jodi Mullet, Francisca N'Kuli, Si Houn Hahn, Patrick Van Der Smissen
Publikováno v:
Molecular Genetics and Metabolism. 109:77-85
Infection of Spodoptera frugiperda (Sf9) cells by baculovirus (BV) is well established for transgene expression of soluble proteins, but few correctly folded transmembrane proteins have been so produced. We here report the use of the BV/Sf9 (BVES) me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc5fd03fcdcfe29f90e8150848651c1
https://doi.org/10.1016/j.ymgme.2013.01.014
https://doi.org/10.1016/j.ymgme.2013.01.014
Autor:
Stanislas Goriely, Pierre J. Courtoy, Abdelatif Elouahabi, Dominique De Wit, Séverine Thomas, Francisca N'Kuli, Romain Gineste, Arnaud M. Didierlaurent, Viviane Bechtold, Sophie Detienne, Iain Welsby, Sandrine Wouters, Thomas Reinheckel
Publikováno v:
Frontiers in Immunology
Frontiers in immunology, 7
Frontiers in immunology, Vol. 7, p. 663 (2017)
Frontiers in Immunology, Vol. 7 (2017) P. 663
Frontiers in immunology, 7
Frontiers in immunology, Vol. 7, p. 663 (2017)
Frontiers in Immunology, Vol. 7 (2017) P. 663
The adjuvant properties of the saponin QS-21 have been known for decades. It is a component of the Adjuvant System AS01 that is used in several vaccine candidates. QS-21 strongly potentiates both cellular and humoral immune responses to purified anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4953cb58cb5d916d140ed57369dcff5c
https://pubmed.ncbi.nlm.nih.gov/28105029
https://pubmed.ncbi.nlm.nih.gov/28105029
Autor:
Pascal Kienlen-Campard, Karelle Leroy, Christine Feyt, Jean Pierre Brion, Francisca N'Kuli, Jean-Noël Octave, Pierre J. Courtoy
Publikováno v:
Journal of Biological Chemistry. 280:33220-33227
Glycogen synthase kinase 3 (GSK3) is able to phosphorylate tau at many sites that are found to be phosphorylated in paired helical filaments in Alzheimer disease. Lithium chloride (LiCl) efficiently inhibits GSK3 and was recently reported to also dec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39741ff79730332dfcd1a660679a6e56
https://doi.org/10.1074/jbc.m501610200
https://doi.org/10.1074/jbc.m501610200
Autor:
Francisca N'Kuli, Pascale Zimmermann, Zhe Zhang, Christien Coomans, Joachim G. Schulz, Eva Mortier, Guido David, Iris Leenaerts, Gisèle Degeest, Pierre J. Courtoy
Publikováno v:
Developmental Cell. 9:377-388
SummarySyndecans are heparan sulfate proteoglycans that modulate the activity of several growth factors and cell adhesion molecules. PDZ domains in the adaptor protein syntenin interact with syndecans and with the phosphoinositide PIP2, which is invo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::213cb0d885a0ea13c0585f57b7226fc5
https://doi.org/10.1016/j.devcel.2005.07.011
https://doi.org/10.1016/j.devcel.2005.07.011