Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Francisca Martín-Gálvez"'
Autor:
Antonio Sánchez-Ruiz, Francisca Martín-Gálvez, Francisco Sarabia, Frederick A. Valeriote, Cristina García-Ruiz
Publikováno v:
ChemMedChem. 8:819-831
Based on our previously described synthetic strategy for bengamide E, a natural product of marine origin with antitumor activity, a small library of analogues modified at the terminal olefinic position was generated with the objective of investigatin
Autor:
Francisca Martín-Gálvez, José F. Tejón-Blanco, Samy Chammaa, Miguel Garcia‐Castro, Francisco Sarabia, Antonio Sánchez-Ruiz
Publikováno v:
The Journal of Organic Chemistry. 73:8979-8986
A new approach to the stereoselective synthesis of polypropionate-type frameworks is reported utilizing reactions of amide-stabilized sulfur ylides with chiral aldehydes. To establish a new strategy for macrolide fragment synthesis, the stereoselecti
Autor:
Francisca Martín-Gálvez, Carlos Vivar-García, Francisco Sarabia, Antonio Sánchez-Ruiz, Cristina García-Ruiz
Publikováno v:
The Journal of organic chemistry. 78(11)
With the objective of investigating the influence of structural modifications of the polyketide chain of the bengamides upon their antitumoral activities, we targeted the preparation of bengamide E analogues with modification of the stereochemistry a
Autor:
Francisca Martín-Gálvez, Miguel Garcia‐Castro, Samy Chammaa, Francisco Sarabia, Cristina García-Ruiz, Carlos Vivar-García, Antonio Sánchez-Ruiz
Publikováno v:
ChemInform. 44
Ylides, generated in situ by the basic treatment of chiral bicyclic sulfonium salts (I) and (II) react with a large variety of aliphatic, aromatic, heteroaromatic, α,β-unsaturated and chiral functionalized aldehydes to trans-epoxy amides with good
Autor:
Carlos Vivar-García, Cristina García-Ruiz, Samy Chammaa, Miguel Garcia‐Castro, Antonio Sánchez-Ruiz, Francisca Martín-Gálvez, Francisco Sarabia
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 18(47)
A new type of chiral sulfonium salts that are characterized by a bicyclic system has been designed and synthesized from α-amino acids. Their corresponding ylides, which were prepared by basic treatment of the sulfonium salts, reacted smoothly with a
Autor:
Francisca Martín-Gálvez, Samy Chammaa, Antonio Sánchez-Ruiz, Laura Martín-Ortiz, Francisco Sarabia
Publikováno v:
The Journal of organic chemistry. 75(16)
A new synthetic methodology of asymmetric epoxidation developed in our laboratories has been employed for the stereoselective synthesis of bengamide E (16) and analogues at the terminal olefinic position. In the event, the chiral sulfonium salt 30 wa
Publikováno v:
ChemInform. 41
A new type of chiral sulfur ylides has been synthesized and their reactivities against carbonyl compounds tested, showing a high degree of stereoselectivity in the formation of transepoxyamides under very mild reaction conditions.
Autor:
Antonio Romero-Carrasco, Carlos Vivar-García, Francisco Sarabia, Antonio Sánchez-Ruiz, Francisca Martín-Gálvez, Cristina García-Ruiz
Publikováno v:
The Journal of Organic Chemistry. 77:9932-9932