Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Francisca Antón"'
Autor:
Joelma Aurélio de Sousa Santos, Christopher Falcão Correia, Francisca Antônia do Vale Gomes, Isabele de Sá Silveira Melo, José Armando Pessoa Neto, Loraine Maria Silva Andrade, Ranna Caroline Bezerra Siebra, Marcellus Henrique Loiola Ponte de Souza, Lúcia Libanez Bessa Campelo Braga Braga
Publikováno v:
Revista de Medicina da UFC, Vol 64, Iss 1, Pp e77941-e77941 (2024)
Introduction: Anti-tumor necrosis factor-alpha agents (Anti-TNF-alpha) are an effective treatment option in patients with moderate and severe inflammatory bowel disease (IBD). Objectives: To evaluate safety profile of infliximab (IFX) and adalilumab
Externí odkaz:
https://doaj.org/article/9fb838442295444eb8ebf20090b23498
Autor:
Maria Antonia Buil, Manuel Fuentes Ferrer, Sonia Espinosa, Francisca Antón, Jordi Castro, Josep M. Huerta, Jorge Beleta, Manuel López, Mònica Córdoba, Dolors Vilella, Montserrat Miralpeix, Gaspar Casals, Maria Prat, Victor Segarra, Maria Dolors Fernández, Hamish Ryder, Marisa González, Alvaro Cardenas, Juan Manuel Monleón, Israel Ramos, Laia Tort, Amadeu Gavaldà
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:1736-1741
Novel quaternary ammonium derivatives of (3R)-quinuclidinyl amides have been identified as potent M3 muscarinic antagonists with a long duration of action in an in vivo model of bronchoconstriction. The synthesis, structure-activity relationships and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::430af71f81dd784dd8e3710b416eebc5
https://doi.org/10.1016/j.bmcl.2015.02.065
https://doi.org/10.1016/j.bmcl.2015.02.065
Autor:
Joan Albertí, Manuel Fuentes Ferrer, Sonia Sentellas, María I. Crespo, Hamish Ryder, Amadeu Gavaldà, Jorge Beleta, Israel Ramos, M. Antonia Buil, Sonia Espinosa, Manuel López, Jordi Castro, Maria Prat, Francisca Antón, Josep M. Huerta, Dolors Fernández, Marisa González, Gaspar Casals, Dolors Vilella, Teresa Doménech, Victor Segarra, Montserrat Miralpeix, Alvaro Cardenas, Juan Manuel Monleón, Laia Tort
Publikováno v:
Journal of Medicinal Chemistry. 52:5076-5092
The objective of this work was to discover a novel, long-acting muscarinic M3 antagonist for the inhaled treatment of chronic obstructive pulmonary disease (COPD), with a potentially improved risk−benefit profile compared with current antimuscarini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45428bc44e0992b58d50d3c5f07d6aa2
https://doi.org/10.1021/jm900132z
https://doi.org/10.1021/jm900132z
Autor:
Carles Puig, Jordi Gras, Elena Calaf, Arantxa Cardús, Lluís Pagès, Jorge Beleta, Montse Miralpeix, Francisca Antón, Graham Warrellow, Hamish Ryder, José Prieto, Alvaro Cardenas, Mònica Aparici, Silvia Fonquerna, Josep M. Huerta, Dolors Vilella
Publikováno v:
Journal of Medicinal Chemistry. 47:6326-6337
A series of indolylpiperidinyl derivatives were prepared and evaluated for their activity as histamine H(1) antagonists. Structure-activity relationship studies were directed toward improving in vivo activity and pharmacokinetic profile of our first
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3f2efad3e23777d79ac1bd1d2cbd9dd
https://doi.org/10.1021/jm0498203
https://doi.org/10.1021/jm0498203
Publikováno v:
Educação em Foco, Vol 27, Iss 1 (2022)
Esta pesquisa aborda as práticas musicais coletivas desenvolvidas no IFCE, Campus de Sobral, por meio dos cursos de extensão de Flauta Doce, Clarineta e Saxofone e Canto Coral. O estudo buscou verificar a repercussão do Ensino Coletivo de Instrume
Externí odkaz:
https://doaj.org/article/5263d9c9be0f454ea18cce495836535f
Autor:
Dolors Vilella, Silvia Fonquerna, Hamish Ryder, Lluís Pagès, Jorge Beleta, Montse Miralpeix, José Prieto, Arantxa Cardús, Graham Warrellow, Carles Puig, Francisca Antón, Mònica Aparici
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:1165-1167
The synthesis and structure–activity relationships of piperidinylpyrrolopyridines as potent and selective H1 antagonists are discussed. It was found that the nature of the acid chain bonded to piperidine was a key feature for maintaining both the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::086b180aebe7d95dcea12ca173e16c39
https://doi.org/10.1016/j.bmcl.2004.12.008
https://doi.org/10.1016/j.bmcl.2004.12.008
Autor:
Martín Martínez-Ripoll, Ibon Alkorta, Francisca Antón, S Juliá, Manuel Grau, Juan A. Páez, E. Carrasco, Pilar Goya
Publikováno v:
ChemInform. 24
The synthesis and evaluation of a new class of diuretic agents derived from the pyrazino[2,3-c][1,2,6]thiadiazine 2,2-dioxide ring system are described. Preliminary structure-activity relationships indicate that the nature and location of the substit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::239628ae91e2ec38e8f5875c17b4a7f4
https://doi.org/10.1002/chin.199321189
https://doi.org/10.1002/chin.199321189
Autor:
Francisca Antón, Joan Albertí, Israel Ramos, Sonia Sentellas, Amadeu Gavaldà, Montserrat Miralpeix, Miquel Salvà, Jorge Beleta
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 39(5)
Aclidinium bromide is a novel, long-acting inhaled muscarinic antagonist drug in Phase III clinical trials for chronic obstructive pulmonary disease (COPD). The aims of this study were to evaluate the in vitro stability of the ester drug aclidinium i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d28a7a812bb01f2f4c3c42b4ada3df7
https://pubmed.ncbi.nlm.nih.gov/20093184
https://pubmed.ncbi.nlm.nih.gov/20093184
Autor:
María, Prat, Dolors, Fernández, M Antonia, Buil, María I, Crespo, Gaspar, Casals, Manuel, Ferrer, Laia, Tort, Jordi, Castro, Juan M, Monleón, Amadeu, Gavaldà, Montserrat, Miralpeix, Israel, Ramos, Teresa, Doménech, Dolors, Vilella, Francisca, Antón, Josep M, Huerta, Sonia, Espinosa, Manuel, López, Sonia, Sentellas, Marisa, González, Joan, Albertí, Victor, Segarra, Alvaro, Cárdenas, Jorge, Beleta, Hamish, Ryder
Publikováno v:
Journal of medicinal chemistry. 52(16)
The objective of this work was to discover a novel, long-acting muscarinic M(3) antagonist for the inhaled treatment of chronic obstructive pulmonary disease (COPD), with a potentially improved risk-benefit profile compared with current antimuscarini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d0fa685f586051a3b9bc091198b8f22d
https://pubmed.ncbi.nlm.nih.gov/19653626
https://pubmed.ncbi.nlm.nih.gov/19653626
Publikováno v:
Chakiñan, Iss 9, Pp 99-108 (2019)
Las vanguardias artísticas de inicios del siglo XX han influenciado de manera directa a todo el acontecer artístico de la actualidad, incluyendo el cinematográfico, que los ha adoptado como parte de la característica intertextual de la posmoderni
Externí odkaz:
https://doaj.org/article/f03fd44c28b54bafb52bfdc251924b4c