Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Francisca Alcayaga-Miranda"'
Autor:
Luis A. Osorio, Mauricio Lozano, Paola Soto, Viviana Moreno-Hidalgo, Angely Arévalo-Gil, Angie Ramírez-Balaguera, Daniel Hevia, Jorge Cifuentes, Yessia Hidalgo, Francisca Alcayaga-Miranda, Consuelo Pasten, Danna Morales, Diego Varela, Cinthya Urquidi, Andrés Iturriaga, Alejandra Rivera-Palma, Ricardo Larrea-Gómez, Carlos E. Irarrázabal
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4913 (2024)
The diagnosis of cardiovascular disease (CVD) is still limited. Therefore, this study demonstrates the presence of human ether-a-go-go-related gene 1 (hERG1) and heat shock protein 47 (Hsp47) on the surface of small extracellular vesicles (sEVs) in h
Externí odkaz:
https://doaj.org/article/8afb9f189fc14744a1e1215790b15a69
Autor:
Francisca Alcayaga-Miranda, Johnatas Dutra Silva, Nicol Parada, Luisa Helena Andrade da Silva, Fernanda Ferreira Cruz, Yildy Utreras, Yessia Hidalgo, María Ignacia Cádiz, Rafael Tapia Limonchi, Francisco Espinoza, Alejandro Bruhn, Maroun Khoury, Patricia R. M. Rocco, Jimena Cuenca
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Background: Treatment for critical care conditions, such as acute respiratory distress syndrome (ARDS), requires ready-to-administer injectable mesenchymal stromal cells (MSCs). A validated cryopreserved therapy based on MSCs derived from menstrual b
Externí odkaz:
https://doaj.org/article/6d96c97ac7c84a49a273372d301c2576
Autor:
Dario Donoso‐Meneses, Aliosha I. Figueroa‐Valdés, Nicolás Georges, Hugo E. Tobar, Francisca Alcayaga‐Miranda
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 1, Pp n/a-n/a (2023)
Abstract Currently, small extracellular vesicles (sEV) as a nanoscale drug delivery system, are undergoing biotechnological scaling and clinical validation. Nonetheless, preclinical pharmacokinetic studies revealed that sEV are predominantly uptaken
Externí odkaz:
https://doaj.org/article/c9aea6a07a714690a7058ad6fb1b0789
Publikováno v:
Journal of Advanced Research, Vol 31, Iss , Pp 61-74 (2021)
Background: Even though exosome-based therapy has been shown to be able to control the progression of different pathologies, the data revealed by pharmacokinetic studies warn of the low residence time of exogenous exosomes in circulation that can hin
Externí odkaz:
https://doaj.org/article/901988f7dabe453f95e109d69dbaf3b1
Autor:
Pamina Contreras-Kallens, Felipe Gálvez-Jirón, Javiera De Solminihac, Ahmed Elhusseiny, Wilfredo A. González-Arriagada, Francisca Alcayaga-Miranda, Randolph J. Noelle, Karina Pino-Lagos
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The suppressive function of T-regulatory cells (Tregs) can have a detrimental effect on immune responses against tumor cells. Within the Treg cells subset, a new non-classical population has been reported, which expresses high levels of CD49b molecul
Externí odkaz:
https://doaj.org/article/fb89aeb0cb9c438baeb441efb27a4fc1
Publikováno v:
Pharmaceutics, Vol 15, Iss 3, p 716 (2023)
Small extracellular vesicles (sEVs) have burst into biomedicine as a natural therapeutic alternative for different diseases. Considered nanocarriers of biological origin, various studies have demonstrated the feasibility of their systemic administrat
Externí odkaz:
https://doaj.org/article/bb541c99db6a4e53992f7afdfc45aa93
Autor:
Aliosha I. Figueroa-Valdés, Catalina de la Fuente, Yessia Hidalgo, Ana María Vega-Letter, Rafael Tapia-Limonchi, Maroun Khoury, Francisca Alcayaga-Miranda
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Cell therapy is witnessing a notable shift toward cell-free treatments based on paracrine factors, in particular, towards small extracellular vesicles (sEV), that mimic the functional effect of the parental cells. While numerous sEV-based application
Externí odkaz:
https://doaj.org/article/0e67b4a08f6745e999d5b9ccf4f11a14
Autor:
Jimena Cuenca, Alice Le-Gatt, Valentina Castillo, Jose Belletti, Macarena Díaz, Mónica Kurte G, Paz L. Gonzalez, Francisca Alcayaga-Miranda, Christina M. A. P. Schuh, Fernando Ezquer, Marcelo Ezquer, Maroun Khoury
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Considerable advances have been made toward understanding the cellular and molecular mechanism of wound healing, however, treatments for chronic wounds remain elusive. Emerging concepts utilizing mesenchymal stem cells (MSCs) from umbilical cord, adi
Externí odkaz:
https://doaj.org/article/08885f14d6c04509b234816f01aacbc1
Publikováno v:
Journal of Advanced Research, Vol 31, Iss, Pp 61-74 (2021)
Journal of Advanced Research
Journal of Advanced Research
Graphical abstract
Background Even though exosome-based therapy has been shown to be able to control the progression of different pathologies, the data revealed by pharmacokinetic studies warn of the low residence time of exogenous exosomes in c
Background Even though exosome-based therapy has been shown to be able to control the progression of different pathologies, the data revealed by pharmacokinetic studies warn of the low residence time of exogenous exosomes in c
Autor:
Dario Donoso‐Meneses, Aliosha I. Figueroa‐Valdés, Nicolás Georges, Hugo E. Tobar, Francisca Alcayaga‐Miranda
Publikováno v:
Bioengineering & Translational Medicine. 8