Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Francisca, Rojas Ringeling"'
Autor:
Florian Hoss, James L. Mueller, Francisca Rojas Ringeling, Juan F. Rodriguez-Alcazar, Rebecca Brinkschulte, Gerald Seifert, Rainer Stahl, Lori Broderick, Chris D. Putnam, Richard D. Kolodner, Stefan Canzar, Matthias Geyer, Hal M. Hoffman, Eicke Latz
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Leucine-rich repeat (LRR) domains are commonly present in immune regulatory proteins. Here the authors show that LRR exonic modularity and alternative splicing of an LRR-containing protein, NLRP3, modulate the ratio of functional/afunctional NLRP3 is
Externí odkaz:
https://doaj.org/article/e8556fbf0c984427a366f6b71e4114ec
Autor:
Valina L. Dawson, Guo Li Ming, Kimberly M. Christian, Stephanie J. Temme, Weidong Li, Stephen M. Eacker, Kuei Sen Hsu, Stefan Canzar, Ki Jun Yoon, Francisca Rojas Ringeling, Ted M. Dawson, Ha Nam Nguyen, Bo Xiao, Paul F. Worley, Yu Ting Lin, Namshik Kim, Hongjun Song, Ying Zhou
Publikováno v:
Biological Psychiatry. 92:815-826
Background Gene dosage imbalance caused by copy number variations (CNVs) is a prominent contributor to brain disorders. In particular, 15q11.2 CNV duplications and deletions have been associated with autism spectrum disorder and schizophrenia, respec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e9e80e80885ae6100fe7ea922e66a0f
https://doi.org/10.1016/j.biopsych.2021.04.023
https://doi.org/10.1016/j.biopsych.2021.04.023
Autor:
Stefan Canzar, Francisca Rojas Ringeling, Martin A. Horstmann, Christoph Klein, Theresa Kaeuferle, Dana Stenger, Mareike Lepenies, Semjon Willier, Franziska Blaeschke, Gabriele Escherich, Vera Binder, Meino Rohlfs, Tobias Feuchtinger, Martin Zimmermann
Publikováno v:
Leukemia. 34:2607-2620
Interaction of malignancies with tissue-specific immune cells has gained interest for prognosis and intervention of emerging immunotherapies. We analyzed bone marrow T cells (bmT) as tumor-infiltrating lymphocytes in pediatric precursor-B cell acute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa4510cdfa01d4582d09b7361a19557a
https://doi.org/10.1038/s41375-020-0793-1
https://doi.org/10.1038/s41375-020-0793-1
Autor:
Ziyuan Guo, Fei Ye, Kimberly M. Christian, Guo Li Ming, Chuan Yu, Wei Zheng, Wei-Kai Huang, Guomin Zhou, Hongjun Song, Francisca Rojas Ringeling, Mingjie Zhang, Yijing Su, Zhexing Wen, Xinyuan Wang
Publikováno v:
Molecular psychiatry
Psychiatric disorders are a collection of heterogeneous mental disorders arising from a contribution of genetic and environmental insults, many of which molecularly converge on transcriptional dysregulation, resulting in altered synaptic functions. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f32b7caef27e950fac46d7b667aaa076
https://doi.org/10.1038/s41380-019-0485-2
https://doi.org/10.1038/s41380-019-0485-2
Autor:
Francisca Rojas Ringeling, Shounak Chakraborty, Caroline Vissers, Derek Reiman, Akshay M. Patel, Ki-Heon Lee, Ari Hong, Chan-Woo Park, Tim Reska, Julien Gagneur, Hyeshik Chang, Maria L. Spletter, Ki-Jun Yoon, Guo-li Ming, Hongjun Song, Stefan Canzar
Publikováno v:
Nature biotechnology. 40(5)
The accuracy of methods for assembling transcripts from short-read RNA sequencing data is limited by the lack of long-range information. Here we introduce Ladder-seq, an approach that separates transcripts according to their lengths before sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34501078e2dc88cd22442c774b0b2351
https://pubmed.ncbi.nlm.nih.gov/35013600
https://pubmed.ncbi.nlm.nih.gov/35013600
Publikováno v:
Genome Res
A fundamental task in single-cell RNA-seq (scRNA-seq) analysis is the identification of transcriptionally distinct groups of cells. Numerous methods have been proposed for this problem, with a recent focus on methods for the cluster analysis of ultra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::030acd121eb626251467a2dd602a512b
https://doi.org/10.1101/2020.06.15.151910
https://doi.org/10.1101/2020.06.15.151910
Autor:
Franziska, Blaeschke, Semjon, Willier, Dana, Stenger, Mareike, Lepenies, Martin A, Horstmann, Gabriele, Escherich, Martin, Zimmermann, Francisca, Rojas Ringeling, Stefan, Canzar, Theresa, Kaeuferle, Meino, Rohlfs, Vera, Binder, Christoph, Klein, Tobias, Feuchtinger
Publikováno v:
Leukemia. 34(10)
Interaction of malignancies with tissue-specific immune cells has gained interest for prognosis and intervention of emerging immunotherapies. We analyzed bone marrow T cells (bmT) as tumor-infiltrating lymphocytes in pediatric precursor-B cell acute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c17f0dd860237f0258251d3d2e99328
https://pubmed.ncbi.nlm.nih.gov/32203137
https://pubmed.ncbi.nlm.nih.gov/32203137
Autor:
Stefan Canzar, Khaled Elbassioni, Pablo Monteagudo, Domagoj Matijevic, Mislav Blazevic, Francisca Rojas Ringeling, Sören Laue, Van Hoan Do, Luka Borozan
Publikováno v:
RECOMB
Single-cell RNA sequencing enables the construction of trajectories describing the dynamic changes in gene expression underlying biological processes such as cell differentiation and development. The comparison of single-cell trajectories under two d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e63afaa0b197d1d029ea60bc8076bf8
Autor:
Gerald Seifert, Florian Hoss, Stefan Canzar, Juan F. Rodriguez-Alcazar, Matthias Geyer, Francisca Rojas Ringeling, Hal M. Hoffman, Rainer Stahl, Christopher D. Putnam, James L. Mueller, Lori Broderick, Eicke Latz, Richard D. Kolodner, Rebecca Brinkschulte
Publikováno v:
Nature Communications 10(1), 3238 (2019). doi:10.1038/s41467-019-11076-1
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature communications, vol 10, iss 1
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature communications, vol 10, iss 1
Leucine-rich repeat (LRR) domains are evolutionarily conserved in proteins that function in development and immunity. Here we report strict exonic modularity of LRR domains of several human gene families, which is a precondition for alternative splic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7956af9e03ff5838d792045b0e2b2f9f
Autor:
Brittany M, Edens, Caroline, Vissers, Jing, Su, Saravanan, Arumugam, Zhaofa, Xu, Han, Shi, Nimrod, Miller, Francisca, Rojas Ringeling, Guo-Li, Ming, Chuan, He, Hongjun, Song, Yongchao C, Ma
Publikováno v:
Cell reports
SUMMARY N6-methyladenosine (m6A) modification of mRNA is emerging as a vital mechanism regulating RNA function. Here, we show that fragile X mental retardation protein (FMRP) reads m6A to promote nuclear export of methylated mRNA targets during neura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37998ba9411992fe02068322f72c1c25
https://pubmed.ncbi.nlm.nih.gov/31340148
https://pubmed.ncbi.nlm.nih.gov/31340148