Zobrazeno 1 - 10
of 250
pro vyhledávání: '"Francis Y, Lee"'
Publikováno v:
Cells, Vol 13, Iss 6, p 522 (2024)
Fracture callus formation is a dynamic stage of bone activity and repair with precise, spatially localized gene expression. Metastatic breast cancer impairs fracture healing by disrupting bone homeostasis and imparting an altered genomic profile. Pre
Externí odkaz:
https://doaj.org/article/a8a5afb55f1f4860917902f035cbcecd
Autor:
Hyuk-Kwon Kwon, Sean V. Cahill, Kristin E. Yu, Kareme D. Alder, Christopher M. Dussik, Jain Jeong, Jung Ho Back, Francis Y. Lee
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
IntroductionDiabetes mellitus (DM) impairs fracture healing and is associated with susceptibility to infection, which further inhibits fracture healing. While intermittent parathyroid hormone (1-34) (iPTH) effectively improves fracture healing, it is
Externí odkaz:
https://doaj.org/article/1eb8782af7ba43ba83ccbf8651255737
Autor:
Hyuk‐Kwon Kwon, Kristin E Yu, Sean V Cahill, Kareme D Alder, Christopher M Dussik, Sang‐Hun Kim, Lokesh Sharma, Jungho Back, Irvin Oh, Francis Y Lee
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 12, Pp 1-19 (2022)
Abstract Intracellular infiltration of bacteria into host cells complicates medical and surgical treatment of bacterial joint infections. Unlike soft tissue infections, septic arthritis and infection‐associated inflammation destroy cartilage that d
Externí odkaz:
https://doaj.org/article/49064c16c4fe45e6a9ef7694bd820bf4
Transcriptomic identification of genes expressed in invasive S. aureus diabetic foot ulcer infection
Autor:
Taiwo Samuel Agidigbi, Hyuk-Kwon Kwon, James R. Knight, Dejian Zhao, Francis Y. Lee, Irvin Oh
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
IntroductionInfection in diabetic foot ulcers (DFUs) is one of the major complications associated with patients with diabetes. Staphylococcus aureus is the most common offending pathogen in patients with infected DFU. Previous studies have suggested
Externí odkaz:
https://doaj.org/article/1d0790a8ddcd40daa84e487e567c4597
Autor:
Jungho Back, Minh Nam Nguyen, Lu Li, Saelim Lee, Inkyu Lee, Fancheng Chen, Lauren Gillinov, Yeon-Ho Chung, Kareme D. Alder, Hyuk-Kwon Kwon, Kristin E. Yu, Christopher M. Dussik, Zichen Hao, Michael J. Flores, Yoseph Kim, Izuchukwu K. Ibe, Alana M. Munger, Sung Wook Seo, Francis Y. Lee
Publikováno v:
Bone Research, Vol 9, Iss 1, Pp 1-14 (2021)
Abstract Disruption of bone homeostasis caused by metastatic osteolytic breast cancer cells increases inflammatory osteolysis and decreases bone formation, thereby predisposing patients to pathological fracture and cancer growth. Alteration of osteob
Externí odkaz:
https://doaj.org/article/be04f427e4a7463ca43298e5ceafb353
Autor:
Hyuk-Kwon Kwon, Christopher M. Dussik, Sang-Hun Kim, Themis R. Kyriakides, Irvin Oh, Francis Y. Lee
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Bacterial infection within the synovial joint, commonly known as septic arthritis, remains a clinical challenge as it presents two concurrent therapeutic goals of reducing bacterial burden and preservation of articular cartilage from destructive host
Externí odkaz:
https://doaj.org/article/fe963741b8504a53bc24a0946915d9fb
Autor:
Joseph B. Kahan, MD, MPH, Christopher A. Schneble, MD, Ryan Applonie, DO, Allen Nicholson, MD, Ian Whittall, BA, Rachel Talley-Bruns, MD, Anna Jorgensen, MD, Nicole LaVette, APRN, Jay Moran, BS, J. Kristopher Ware, MD, Francis Y. Lee, MD, PhD, Theodore A. Blaine, MD
Publikováno v:
JSES Reviews, Reports, and Techniques, Vol 1, Iss 2, Pp 96-101 (2021)
Background: There is wide variability in surgical technique for biceps tenodesis. Prior biomechanical studies have demonstrated superior ultimate and fatigue strength with a Krakow-type locked loop when compared with simple suture and lasso-loop conf
Externí odkaz:
https://doaj.org/article/160fdd7955364da88208d84079c6df6f
Autor:
Hyuk-Kwon Kwon, Mahesh Chandra Patra, Hyeon-Jun Shin, Xiangai Gui, Asma Achek, Suresh Panneerselvam, Dong-Jin Kim, Suk-Jong Song, Riwon Hong, Kyoung Soo Kim, Yang Gyun Kim, Francis Y. Lee, Dae-Hyun Hahm, Sang Ho Lee, Sangdun Choi
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 4, Pp 1-19 (2019)
Inflammation: A decoy peptide treats arthritis and sepsis in mice A newly discovered peptide drug that disrupts signaling through a critical immune pathway could offer a new treatment for inflammatory diseases. Sangdun Choi from Ajou University in Su
Externí odkaz:
https://doaj.org/article/d6e0d5885d2f46d4af80b5803f5e237b
Publikováno v:
CardioVascular and Interventional Radiology. 46:649-657
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c38fbea01dfad5f39af914c6ad369c49
https://doi.org/10.1007/s00270-023-03425-x
https://doi.org/10.1007/s00270-023-03425-x
Autor:
Kristin E. Yu, Kareme D. Alder, Montana T. Morris, Alana M. Munger, Inkyu Lee, Sean V. Cahill, Hyuk-Kwon Kwon, JungHo Back, Francis Y. Lee
Publikováno v:
Therapeutic Advances in Musculoskeletal Disease, Vol 12 (2020)
Naringin is a naturally occurring flavonoid found in plants of the Citrus genus that has historically been used in traditional Chinese medical regimens for the treatment of osteoporosis. Naringin modulates signaling through numerous molecular pathway
Externí odkaz:
https://doaj.org/article/9293324847c344d4992a1f94ae7b1695