Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Francis X. Pizza"'
Autor:
Francis X. Pizza, Kole H. Buckley
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12545 (2023)
Injury to skeletal muscle through trauma, physical activity, or disease initiates a process called muscle regeneration. When injured myofibers undergo necrosis, muscle regeneration gives rise to myofibers that have myonuclei in a central position, wh
Externí odkaz:
https://doaj.org/article/677bbd2b6d3e40059dab1c749232ef40
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Fundamental aspects underlying downstream processes of skeletal muscle regeneration, such as myonuclear positioning and transcription are poorly understood. This investigation begins to address deficiencies in knowledge by examining the kinetics of m
Externí odkaz:
https://doaj.org/article/d542f6a4fb8d442da745bac448977bc7
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7028 (2022)
The local inflammatory environment of injured skeletal muscle contributes to the resolution of the injury by promoting the proliferation of muscle precursor cells during the initial stage of muscle regeneration. However, little is known about the ext
Externí odkaz:
https://doaj.org/article/79852bfe1cc446f09dbcf57226c7b883
Autor:
Francis X. Pizza, Ryan A. Martin, Evan M. Springer, Maxwell S. Leffler, Bryce R. Woelmer, Isaac J. Recker, Douglas W. Leaman
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Abstract The overall objective of the study was to identify mechanisms through which intercellular adhesion molecule-1 (ICAM-1) augments the adhesive and fusogenic properties of myogenic cells. Hypotheses were tested using cultured myoblasts and fibr
Externí odkaz:
https://doaj.org/article/78c6672c4e6d4197937075dfb4cc74d0
Fundamental aspects underlying downstream processes of skeletal muscle regeneration, such as myonuclear positioning and transcription are poorly understood. This investigation begins to address deficiencies in knowledge by examining the kinetics of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8c07be8c8b41336bef925b1966615b6
https://doi.org/10.1101/2022.02.11.480101
https://doi.org/10.1101/2022.02.11.480101
Autor:
Alena N. Sidwell, Randall G. Worth, Benjamin M. Riley, Stephanie L. Douglas, Francis X. Pizza, Ryan A. Martin, Kole H. Buckley, Drew C. Mankowski
Publikováno v:
Am J Pathol
This study investigated intercellular adhesion molecule-1 (ICAM-1), a membrane protein that mediates cell-to-cell adhesion and communication, as a mechanism through which the inflammatory response facilitates muscle regeneration after injury. Toxin-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c48589d0ee328e377ba61828e81d5bd4
https://europepmc.org/articles/PMC7527860/
https://europepmc.org/articles/PMC7527860/
Autor:
Maria Jose Torres-Palsa, Jennifer M. Peterson, Qingnian Goh, Matthew V. Koziol, Peter A. Cicinelli, Francis X. Pizza
Publikováno v:
Muscle & Nerve. 52:795-802
Introduction: We investigated the extent to which intercellular adhesion molecule-1 (ICAM-1), a critical protein of the inflammatory response, is expressed in skeletal muscles of mdx mice (a murine model of Duchenne muscular dystrophy). Methods: Musc
Autor:
Francis X, Pizza, Brian C, Clark, Ronald E, De Meersman, Stuart M, Phillips, Nicole, Stupka, Sarianna, Sipila, Vuokko, Kovanen, Harri, Suominen, Gordon L, Warren, Dawn A, Lowe, Mary P, Miles, Stephan, Sorichter, Stephan, Walterspacher, Stephen P, Sayers, Kathleen J, Savage
Publikováno v:
Journal of Applied Physiology. 106:1016-1020
to the editor: Interpretations on the effect of estrogen/sex should be based on direct measures of muscle injury and subsequent repair/regeneration (i.e., improvements in muscle structure and function after injurious exercise). The inclusion of index
Autor:
Francis X. Pizza, Jennifer M. Peterson
Publikováno v:
Journal of Applied Physiology. 106:130-137
We tested the hypothesis that cytokines derived from differentiated skeletal muscle cells in culture induce neutrophil chemotaxis after mechanical strain. Flexible-bottom plates with cultured human muscle cells attached were exposed to mechanical str
Autor:
Thomas J. McLoughlin, Marc V. Manacci, Brian J. Tausch, Samuel J. Rakyta, Christopher L. Dearth, Joseph S. Marino, Francis X. Pizza, Matthew P. Linsenmayer
Publikováno v:
American Journal of Physiology-Cell Physiology. 295:C1026-C1036
We tested the contribution of β2-integrins, which are important for normal function of neutrophils and macrophages, to skeletal muscle hypertrophy after mechanical loading. Using the synergist ablation model of hypertrophy and mice deficient in the