Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Francis X. Muller"'
Publikováno v:
International Journal of Pharmaceutics. 348:46-53
Methacrylic acid copolymers have been shown to enhance release of weakly basic drugs from rate controlling polymer matrices through the mechanism of microenvironmental pH modulation. Since these matrices are typically formed through a compaction proc
Publikováno v:
Journal of the American Chemical Society. 127:6641-6651
Structural and solid-state changes of piroxicam in its crystalline form under mechanical stress were investigated using cryogenic grinding, powder X-ray diffractometry, diffuse-reflectance solid-state ultraviolet-visible spectroscopy, variable-temper
Publikováno v:
Journal of Pharmaceutical Sciences. 93:3013-3026
The dehydration kinetics of piroxicam monohydrate ( PM ) is analyzed by both model‐free and model‐fitting approaches. The conventional model‐fitting approach assuming a fixed mechanism throughout the reaction is found to be too simplistic. The
Publikováno v:
Crystal Growth & Design. 5:571-578
The local structures of amorphous phases of piroxicam were studied to explain differences in their recrystallization behavior, which we reported earlier (Sheth, A. R.; Bates, S.; Muller, F. X.; Grant, D. J. W. Polymorphism in piroxicam. Cryst. Growth
Publikováno v:
Journal of Pharmaceutical Sciences. 93:2669-2680
The goal of the present work was to understand the effect of relative humidity (RH) and temperature on the molecular structure, crystal structure, and physical properties of warfarin sodium 2-propanol solvate (W). After previous determination of the
Publikováno v:
Crystal Growth & Design. 4:1091-1098
Piroxciam is a polymorphic drug. However, reports on the number and nomenclature of the polymorphs of piroxicam and the complete hydrogen-bonding patterns of piroxicam molecules in the crystal forms are in conflict and are sources of confusion, which
Publikováno v:
International Journal of Pharmaceutics. 233:99-109
To investigate the powder plug formation process of silicified microcrystalline cellulose (SMCC) under compression forces consistent with automatic capsule-filling machines, a single-ended saw-tooth wave was used to make powder plugs with different h
Publikováno v:
Pharmaceutical Development and Technology. 4:209-219
The objective of this study was to simulate powder plug formation and explore the low-force powder compression physics of the process. A single-ended saw-tooth waveform was used to make powder plugs, representing no. 1 size capsules, at constant punc
Autor:
Domenick Argenti, Manuel Vincente Sanchez-Felix, Barbara M. Davit, Jack Cook, Nancy P. Barbour, Francis X. Muller, Amitava Mitra, Shoufeng Li, Alfredo García-Arieta, Vivek S. Purohit, Kerry John Hartauer, James E. Polli, John W. Skoug, Jean-Marie Geoffroy, K. Tang, Paul A. Dickinson
This summary workshop report highlights presentations and over-arching themes from an October 2011 workshop. Discussions focused on best practices in the application of biopharmaceutics in oral drug product development and evolving bioequivalence app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd5eef778c08dda5a1a0d8462305a51b
https://europepmc.org/articles/PMC3385831/
https://europepmc.org/articles/PMC3385831/
Publikováno v:
Pharmaceutical development and technology. 8(3)
The purpose of this study was a comparative evaluation of miniaturized vs. University of Minnesota's (i.e., U of Minn. = Hiestand's) procedures for determining the tensile strength, indentation hardness, and bonding index (BI), one out of three Indic